Jacksonville River Cruise Departures

River Cruises that depart from North America: United States: Florida: Jacksonville

River Cruises that visit Jacksonville

See all Cruises that depart from Jacksonville

Click on a cruise ship itinerary sailing from Jacksonville (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Jacksonville), please visit: Cruise Search or try our Virtual Cruise Advisor™.

7 Night - Great Rivers of Florida Cruise
Starting in Jacksonville, FL, Green Cove Springs, FL, Palatka, FL, Amelia Island, FL, Cruising the Tolomato River, St Augustine, FL, Jacksonville, FL
2025 Sails: Nov 28, Dec 20, Dec 27, 2026: Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, Mar 12, Nov 21, Nov 28, Dec 5, Dec 12, Dec 19, Dec 26, 2027: Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, May 15, More...

American Cruise Lines, American Liberty

7 Night - Great Rivers of Florida Cruise
Starting in Jacksonville, FL, Green Cove Springs, FL, Palatka, FL, Amelia Island, FL, Cruising the Tolomato River, St Augustine, FL, Jacksonville, FL
2028 Sails: Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 4, Mar 11, Mar 18, Mar 25, Apr 1, Apr 8, Apr 15, Apr 22, Apr 29, More...

Jacksonville River Cruise Departures