Jacksonville River Cruise Departures

River Cruises that depart from North America: United States: Florida: Jacksonville

River Cruises that visit Jacksonville

See all Cruises that depart from Jacksonville

Click on a cruise ship itinerary sailing from Jacksonville (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Jacksonville), please visit: Cruise Search or try our Virtual Cruise Advisor™.

8 Night - Great Rivers of Florida Cruise
Starting in Jacksonville, FL, Day of Cruising, Green Cove Springs, FL, Amelia Island, FL, Cruising the Tolomato River, St Augustine, FL, Jacksonville, FL
2026 Sails: Mar 4, Mar 11, Nov 21, Nov 28, Dec 5, Dec 12, Dec 19, 2027: Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, Mar 12, May 14, Nov 22, Nov 29, Dec 6, Dec 12, Dec 19, Dec 27, 2028: May 12, Nov 27, Dec 4, More...

American Cruise Lines, American Liberty

8 Night - Great Rivers of Florida Cruise
Starting in Jacksonville, FL, Day of Cruising, Green Cove Springs, FL, Amelia Island, FL, Cruising the Tolomato River, St Augustine, FL, Jacksonville, FL
2028 Sails: Jan 28, Feb 4, Feb 11, Feb 18, Feb 25, Mar 3, Mar 10, Mar 17, Mar 24, Mar 31, Apr 7, Apr 14, Apr 21, Apr 28, More...

Jacksonville River Cruise Departures