Colon Cruise Departures
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...10 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, San Blas Islands, Cartagena, Santa Marta, Bonaire, Tobago Cays, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Mar 12, More...
7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama
2027 Sails: Mar 13, Mar 27, More...
13 Night - Central America from Colon to Cozumel
Starting in Colon, San Blas Islands, Bocas del Toro, Puerto Limon, Isla Guanaja, French Key, Belize City, Lighthouse Reef / Half Moon Caye, Cozumel, Mexico
2027 Sails: Mar 13, More...
10 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, San Blas Islands, Cartagena, Santa Marta, Bonaire, Mayreau Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Apr 8, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Apr 10, More...7 Night - Colon to San Juan Cruise
Starting in Colon, Panama, Kingstown, St Vincent, Castries, St Lucia, St Johns AG, Antigua, Tortola, San Juan, Puerto Rico
2027 Sails: Apr 24, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Dec 4, Dec 11, Dec 25, 2028: Jan 29, Feb 5, Feb 12, Mar 11, Mar 25, Apr 22, More...
7 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...10 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour
Starting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera, Santa Elena (Monteverde), La Fortuna (Arenal), Costa Rica, Puerto Caldera, San Jose, Costa Rica
2027 Sails: Dec 6, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
Click on a cruise ship itinerary sailing from Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...
10 Night - Panama, Colombia & Caribbean IslandsStarting in Colon, San Blas Islands, Cartagena, Santa Marta, Bonaire, Tobago Cays, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Mar 12, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama
2027 Sails: Mar 13, Mar 27, More...
13 Night - Central America from Colon to CozumelStarting in Colon, San Blas Islands, Bocas del Toro, Puerto Limon, Isla Guanaja, French Key, Belize City, Lighthouse Reef / Half Moon Caye, Cozumel, Mexico
2027 Sails: Mar 13, More...
10 Night - Panama, Colombia & Caribbean IslandsStarting in Colon, San Blas Islands, Cartagena, Santa Marta, Bonaire, Mayreau Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Apr 8, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Apr 10, More...
7 Night - Colon to San Juan CruiseStarting in Colon, Panama, Kingstown, St Vincent, Castries, St Lucia, St Johns AG, Antigua, Tortola, San Juan, Puerto Rico
2027 Sails: Apr 24, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Dec 4, Dec 11, Dec 25, 2028: Jan 29, Feb 5, Feb 12, Mar 11, Mar 25, Apr 22, More...
7 Night - Costa Rica & Panama CanalStarting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
10 Night - Monteverde Cloud Forest & Arenal Volcano Cruise TourStarting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera, Santa Elena (Monteverde), La Fortuna (Arenal), Costa Rica, Puerto Caldera, San Jose, Costa Rica
2027 Sails: Dec 6, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
