Colon Cruise Departures
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
10 Night - Secrets of Central America
Starting in Colon, Portobelo, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Playa San Josecito, Golfo Dulce, Puerto Jimenez, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 25, 2028: Nov 20, 2029: Jan 6, More...
7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Dec 29, More...
7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2028 Sails: Jan 1, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2028 Sails: Jan 8, More...7 Night - Panama and Costa Rica by Sea : the Natural Wonders of Central America - with Smithsonian Journeys
Starting in Colon, Portobelo, San Blas Islands, Crossing the Panama Canal, Balboa, Quepos, Puntarenas
2028 Sails: Jan 12, More...
9 Night - Panama to Costa Rica
Starting in Colon, Panama, Panama Canal Transit, Isla Del Rey / Pearl Islands, Panama, Isla Iguana, Panama, Coiba National Park, Panama, Marine Park Golfo De Chiriqui / Parida Island, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Islas Tortugas, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Jan 20, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2028 Sails: Jan 22, Feb 26, Mar 4, Apr 8, More...12 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, Portobelo, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Mayreau Island, Port Elizabeth VC, Bequia Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2028 Sails: Mar 4, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2028 Sails: Mar 18, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2028 Sails: Apr 1, More...
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
Click on a cruise ship itinerary sailing from Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Secrets of Central AmericaStarting in Colon, Portobelo, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Playa San Josecito, Golfo Dulce, Puerto Jimenez, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 25, 2028: Nov 20, 2029: Jan 6, More...
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Dec 29, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2028 Sails: Jan 1, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2028 Sails: Jan 8, More...
7 Night - Panama and Costa Rica by Sea : the Natural Wonders of Central America - with Smithsonian JourneysStarting in Colon, Portobelo, San Blas Islands, Crossing the Panama Canal, Balboa, Quepos, Puntarenas
2028 Sails: Jan 12, More...
9 Night - Panama to Costa RicaStarting in Colon, Panama, Panama Canal Transit, Isla Del Rey / Pearl Islands, Panama, Isla Iguana, Panama, Coiba National Park, Panama, Marine Park Golfo De Chiriqui / Parida Island, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Islas Tortugas, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Jan 20, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2028 Sails: Jan 22, Feb 26, Mar 4, Apr 8, More...
12 Night - Panama, Colombia & Caribbean IslandsStarting in Colon, Portobelo, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Mayreau Island, Port Elizabeth VC, Bequia Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2028 Sails: Mar 4, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2028 Sails: Mar 18, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2028 Sails: Apr 1, More...
