Colon Cruise Departures
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama
2027 Sails: Feb 13, More...
12 Night - Cruise from Colon to Puntarenas
Starting in Colon, San Blas Islands, Transit Panama Canal, Pearl Islands, Puerto Jimenez, Playa Mantas / Punta Leona, Quepos, Marina Flamingo / Playa Flamingo, Playa Panama, Puntarenas
2027 Sails: Feb 17, More...
7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...10 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Tobago Cays, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Mar 12, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama
2027 Sails: Mar 13, Mar 27, More...12 Night - Central America from Colon to Cozumel
Starting in Colon, San Blas Islands, Bocas del Toro, Puerto Limon, Isla Guanaja, French Key, Belize City, Lighthouse Reef / Half Moon Caye, Cozumel, Mexico
2027 Sails: Mar 13, More...
10 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Mayreau Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Apr 8, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Apr 10, More...7 Night - Colon to San Juan Cruise
Starting in Colon, Panama, Kingstown, St Vincent, Castries, St Lucia, St Johns AG, Antigua, Tortola, San Juan, Puerto Rico
2027 Sails: Apr 24, More...10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Nov 28, More...
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
Click on a cruise ship itinerary sailing from Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama
2027 Sails: Feb 13, More...
12 Night - Cruise from Colon to PuntarenasStarting in Colon, San Blas Islands, Transit Panama Canal, Pearl Islands, Puerto Jimenez, Playa Mantas / Punta Leona, Quepos, Marina Flamingo / Playa Flamingo, Playa Panama, Puntarenas
2027 Sails: Feb 17, More...
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...
10 Night - Panama, Colombia & Caribbean IslandsStarting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Tobago Cays, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Mar 12, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama
2027 Sails: Mar 13, Mar 27, More...
12 Night - Central America from Colon to CozumelStarting in Colon, San Blas Islands, Bocas del Toro, Puerto Limon, Isla Guanaja, French Key, Belize City, Lighthouse Reef / Half Moon Caye, Cozumel, Mexico
2027 Sails: Mar 13, More...
10 Night - Panama, Colombia & Caribbean IslandsStarting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Mayreau Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Apr 8, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Apr 10, More...
7 Night - Colon to San Juan CruiseStarting in Colon, Panama, Kingstown, St Vincent, Castries, St Lucia, St Johns AG, Antigua, Tortola, San Juan, Puerto Rico
2027 Sails: Apr 24, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Nov 28, More...
