Colon Cruise Departures
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
12 Night - Central America from Colon to Cozumel
Starting in Colon, San Blas Islands, Bocas del Toro, Puerto Limon, Isla Guanaja, French Key, Belize City, Lighthouse Reef / Half Moon Caye, Cozumel, Mexico
2027 Sails: Mar 13, More...
10 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Mayreau Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Apr 8, More...
7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Apr 10, More...7 Night - Colon to San Juan Cruise
Starting in Colon, Panama, Kingstown, St Vincent, Castries, St Lucia, St Johns AG, Antigua, Tortola, San Juan, Puerto Rico
2027 Sails: Apr 24, More...10 Night - Secrets of Central America
Starting in Colon, Portobelo, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Playa San Josecito, Golfo Dulce, Puerto Jimenez, Curu Wildlife Refuge, Puntarenas
2027 Sails: Nov 28, More...
10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 2, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Dec 4, Dec 11, Dec 25, 2028: Jan 29, Feb 5, Feb 12, Mar 11, Mar 25, Apr 22, More...
7 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose, Santa Elena (Monteverde), El Establo Mountain Hotel or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, San Jose, Costa Rica Marriott Hotel Hacienda Belen or Similar, Juan Santamaria International
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2027 Sails: Dec 18, 2028: Jan 15, Feb 19, Apr 15, More...
Cruises that depart from Central America: Panama: Colon
Cruises that visit Colon
Click on a cruise ship itinerary sailing from Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
12 Night - Central America from Colon to CozumelStarting in Colon, San Blas Islands, Bocas del Toro, Puerto Limon, Isla Guanaja, French Key, Belize City, Lighthouse Reef / Half Moon Caye, Cozumel, Mexico
2027 Sails: Mar 13, More...
10 Night - Panama, Colombia & Caribbean IslandsStarting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Mayreau Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Apr 8, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Apr 10, More...
7 Night - Colon to San Juan CruiseStarting in Colon, Panama, Kingstown, St Vincent, Castries, St Lucia, St Johns AG, Antigua, Tortola, San Juan, Puerto Rico
2027 Sails: Apr 24, More...
10 Night - Secrets of Central AmericaStarting in Colon, Portobelo, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Playa San Josecito, Golfo Dulce, Puerto Jimenez, Curu Wildlife Refuge, Puntarenas
2027 Sails: Nov 28, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 2, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Dec 4, Dec 11, Dec 25, 2028: Jan 29, Feb 5, Feb 12, Mar 11, Mar 25, Apr 22, More...
7 Night - Costa Rica & Panama CanalStarting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise TourStarting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose, Santa Elena (Monteverde), El Establo Mountain Hotel or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, San Jose, Costa Rica Marriott Hotel Hacienda Belen or Similar, Juan Santamaria International
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2027 Sails: Dec 18, 2028: Jan 15, Feb 19, Apr 15, More...
