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Colon Cruise Departures

Cruises that depart from Central America: Panama: Colon

Cruises that visit Colon

Click on a cruise ship itinerary sailing from Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Colon
Shore Excursions

PONANT, Le Bougainville
Le Bougainville7 Night - Panama and Costa Rica by Sea : the Natural Wonders of Central America - with Smithsonian Journeys
Starting in Colon, Portobelo, San Blas Islands, Crossing the Panama Canal, Balboa, Quepos, Puntarenas
2028 Sails: Jan 12, More...
PONANT, Le Bougainville
Le Bougainville12 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, Portobelo, San Blas Islands, Cartagena, Santa Marta, Bonaire, Mayreau Island, Port Elizabeth VC, Bequia Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2028 Sails: Mar 4, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2028 Sails: Mar 18, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2028 Sails: Apr 1, More...
PONANT, Le Bellot
Le Bellot12 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, Portobelo, San Blas Islands, Cartagena, Santa Marta, Bonaire, Mayreau Island, Port Elizabeth VC, Bequia Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2028 Sails: Apr 11, More...

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Colon Cruise Departures