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United States River Cruise Departures

River Cruises that depart from North America: United States

River Cruises that visit United States

See all Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Alabama : Florida : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Washington : Washington DC : Wyoming


American Lines Tours, American Anthem Tours
American Anthem Tours14 Night - National Parks & Legendary Rivers
Starting in Jackson, WY, Grand Teton and Yellowstone National Parks, Yellowstone National Park, Travel toward Glacier National Park, Glacier National Park, Travel to Clarkston, Begin Your Columbia River and Snake Rivers Cruise / Clarkston, WA, Richland, WA, Cruising the Columbia River Gorge, Hood River, OR, Kalama, WA, Astoria, Or, Day of Cruising, Portland-OR
2028 Sails: Jun 10, Jun 24, Jul 8, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, More...
Viking River, Viking Mississippi
Viking Mississippi21 Night - Mississippi River Odyssey
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois, Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2028 Sails: Jul 11, More...
American Cruise Lines, American Maverick
American Maverick8 Night - Hudson River Fall Foliage Cruise
Starting in New York, NY, Day of Cruising the Hudson River, Sleepy Hollow, NY, West Point, NY, Kingston, NY / Hyde Park, NY, Catskill, NY, Day of Cruising, Albany NY
2028 Sails: Oct 1, Oct 15, Oct 29, More...
American Cruise Lines, American Maverick
American Maverick8 Night - Hudson River Fall Foliage Cruise
Starting in Albany NY, Cruising the Hudson River, Catskill, NY, Kingston, NY / Hyde Park, NY, Day of Cruising, West Point, NY, Sleepy Hollow, NY, New York, NY
2028 Sails: Oct 8, Oct 22, Nov 5, More...
American Cruise Lines, American Symphony
American Symphony7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2028 Sails: Nov 14, Nov 20, Nov 26, Dec 2, Dec 9, Dec 14, Dec 20, Dec 26, More...
Viking River, Viking Mississippi
Viking Mississippi7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2028 Sails: Dec 12, More...
Viking River, Viking Mississippi
Viking Mississippi7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2028 Sails: Dec 19, Dec 26, More...

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United States River Cruise Departures