United States River Cruise Departures

River Cruises that depart from North America: United States

River Cruises that visit United States

See all Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Alabama : Florida : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Washington : Washington DC : Wyoming

American Cruise Lines, American Navigator

8 Night - Northeast Harbors Cruise
Starting in Boston, Ma, Day of Cruising, Plymouth, MA, Newport, Ri, New London / Mystic, CT, Sag Harbor, NY, Old Saybrook, CT, New York, NY
2027 Sails: Sep 17, Oct 1, 2028: Oct 20, More...

American Cruise Lines, American Symphony

15 Night - Grand Heartland Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Dubuque, IA, Davenport, IA, Day of Cruising, Hannibal, MO, Day of River Cruising, St Louis, MO, Memphis, TN, Tunica, MS, Day of Cruising, Vicksburg, MS, Natchez, MS, Baton Rouge, LA, New Orleans, La
2027 Sails: Sep 17, 2028: Oct 18, More...

American Cruise Lines, American Splendor

15 Night - Mississippi & Cumberland Rivers Cruise
Starting in Nashville, TN, Cruising the Mississippi River, Clarksville, TN, Dover TN, Day of River Cruising, Paducah, KY, Day of Cruising, Memphis, TN, Day of River Cruising, Vicksburg, MS, Natchez, MS, Day of River Cruising, Baton Rouge, LA, Oak Alley, LA, New Orleans, La
2027 Sails: Sep 21, 2028: Oct 17, More...

American Cruise Lines, American Navigator

8 Night - Northeast Harbors Cruise
Starting in New York, NY, Cruising the Hudson River, Sag Harbor, NY, Old Saybrook, CT, New London / Mystic, CT, Newport, Ri, Day of Cruising, Plymouth, MA, Boston, Ma
2027 Sails: Sep 24, More...

American Cruise Lines, American Mariner

8 Night - Hudson River Fall Foliage Cruise
Starting in New York, NY, Day of Cruising the Hudson River, Sleepy Hollow, NY, West Point, NY, Kingston, NY / Hyde Park, NY, Catskill, NY, Day of Cruising, Albany NY
2027 Sails: Oct 1, Oct 15, Oct 29, 2028: Sep 24, Oct 8, Oct 22, More...

American Cruise Lines, American Maverick

15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Oct 4, 2028: Sep 17, More...

American Cruise Lines, American Mariner

8 Night - Hudson River Fall Foliage Cruise
Starting in Albany NY, Cruising the Hudson River, Catskill, NY, Kingston, NY / Hyde Park, NY, Day of Cruising, West Point, NY, Sleepy Hollow, NY, New York, NY
2027 Sails: Oct 8, Oct 22, Nov 5, 2028: Oct 1, Oct 15, Oct 29, More...

American Cruise Lines, American Navigator

American Cruise Lines, American Serenade

11 Night - Mississippi Explorer Cruise
Starting in Memphis, TN, Cruising the Mississippi River, Tunica, MS, Day of River Cruising, Cleveland, MS, Vicksburg, MS, Day of River Cruising, Natchez, MS, St Francisville, LA, Oak Alley, LA, New Orleans, La
2027 Sails: Oct 18, More...

<= Back

More =>

United States River Cruise Departures