St Louis Cruises
Cruises that visit North America: United States: Missouri: St Louis
Cruises that depart from St Louis
See all River Cruises that visit St Louis
22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: May 22, 2027: May 21, 2028: Jun 3, More...8 Night - Upper Mississippi River Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jun 12, Aug 21, Sep 4, Sep 18, Oct 2, 2027: Jun 11, Sep 3, Sep 17, Oct 1, 2028: Jun 24, Sep 2, Sep 16, Sep 30, More...
22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jun 12, 2027: Jun 11, 2028: Jun 10, More...
14 Night - The Big Easy to the Gateway City
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois
2026 Sails: Jun 13, More...8 Night - Upper Mississippi River Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...14 Night - America's Great River
Starting in St Paul, Minnesota, Red Wing, Minnesota, La Crosse, Wisconsin, Dubuque, Iowa, Quad Cities, Iowa, Burlington, Iowa, Hannibal, Missouri, St Louis, Missouri, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jul 4, More...21 Night - Mississippi River Odyssey
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois, Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2026 Sails: Jul 18, More...14 Night - The Big Easy to the Gateway City
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois
2026 Sails: Jul 18, More...15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Jul 31, 2027: Aug 13, 2028: Aug 12, More...
15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Aug 21, 2027: Aug 27, 2028: Aug 26, More...
Cruises that visit North America: United States: Missouri: St Louis
Cruises that depart from St Louis
See all River Cruises that visit St Louis
Click on a cruise ship itinerary that visits St Louis (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just St Louis), please visit: Cruise Search or try our Virtual Cruise Advisor™.
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: May 22, 2027: May 21, 2028: Jun 3, More...
8 Night - Upper Mississippi River CruiseStarting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jun 12, Aug 21, Sep 4, Sep 18, Oct 2, 2027: Jun 11, Sep 3, Sep 17, Oct 1, 2028: Jun 24, Sep 2, Sep 16, Sep 30, More...
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jun 12, 2027: Jun 11, 2028: Jun 10, More...
14 Night - The Big Easy to the Gateway CityStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois
2026 Sails: Jun 13, More...
8 Night - Upper Mississippi River CruiseStarting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
14 Night - America's Great RiverStarting in St Paul, Minnesota, Red Wing, Minnesota, La Crosse, Wisconsin, Dubuque, Iowa, Quad Cities, Iowa, Burlington, Iowa, Hannibal, Missouri, St Louis, Missouri, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jul 4, More...
21 Night - Mississippi River OdysseyStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois, Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2026 Sails: Jul 18, More...
14 Night - The Big Easy to the Gateway CityStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois
2026 Sails: Jul 18, More...
15 Night - Grand Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Jul 31, 2027: Aug 13, 2028: Aug 12, More...
15 Night - Grand Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Aug 21, 2027: Aug 27, 2028: Aug 26, More...
