CruiseCompete: Easily Compare Multiple Offers from Cruise Experts
Compare offers from multiple travel agencies
1
Find your cruise
& request quotes
2
Compare members only prices,
upgrades, cabin credits & more!
3
Contact your preferred agent
for questions or to book your cruise
Over 1 million members
St Louis River Cruises

River Cruises that visit North America: United States: Missouri: St Louis

River Cruises that depart from St Louis

See all Cruises that visit St Louis

Mississippi River Cruises

Click on a cruise ship itinerary that visits St Louis (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just St Louis), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name


Queen of the Mississippi Cruises10 Night - Ohio River Cruise from St. Louis to Pittsburgh, PA
Starting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Louisville, KY; Cincinnati, OH; Maysville, KY; Marietta, OH; Pittsburgh, PA
2021 Sails: Aug 10, Aug 30, Sep 19, 2022: Aug 6, Aug 26, Sep 15, 2023: Aug 5, Aug 25, More...
America Cruises14 Night - Grand Heartland Cruise from St. Paul, MN to New Orleans, LA
Starting in St. Paul, MN; with stops in Red Wing, MN;Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2021 Sails: Aug 11, Oct 23, 2022: Aug 10, Oct 22, 2023: Aug 9, Oct 21, More...
American Countess Cruises8 Night - American Culinary Experience River Cruise from Memphis to St. Louis (Alton)
Starting in Memphis, TN; with stops in New Madrid, MO; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO (Alton)
2021 Sails: Aug 14, More...
Queen of the Mississippi Cruises10 Night - Ohio River Cruise from Pittsburgh, PA to St. Louis
Starting in Pittsburgh, PA; with stops in Marietta, OH; Maysville, KY; Cincinnati, OH; Louisville, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2021 Sails: Aug 20, Sep 9, Sep 29, 2022: Aug 16, Sep 5, Sep 25, 2023: Aug 15, More...
America Cruises10 Night - Mississippi River Gateway Cruise from New Orleans, LA to St. Louis, MO
Starting in New Orleans, LA; with stops in Baton Rouge, LA; Natchez, MS; Vicksburg, MS; Memphis, TN; New Madrid, MO; Paducah, KY; St. Louis, MO
2021 Sails: Aug 25, 2022: Jul 10, Aug 24, 2023: Jul 9, Aug 23, More...
American Countess Cruises15 Night - Minneapolis (Red Wing) to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2021 Sails: Aug 28, 2022: Sep 26, 2023: Sep 4, More...
American Melody Cruises21 Night - Complete Mississippi River Cruise from New Orleans, LA to St. Paul, MN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2021 Sails: Sep 3, 2022: Jun 10, 2023: Jun 9, More...
America Cruises7 Night - Upper Mississippi River Cruise from St. Paul, MN to St. Louis, MO
Starting in St. Paul, MN; with stops in Red Wing, MN; Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO
2021 Sails: Sep 11, Sep 25, Oct 9, 2022: Jul 27, Sep 10, Sep 24, Oct 8, 2023: Jul 26, Sep 9, Sep 23, Oct 7, More...
American Melody Cruises7 Night - Upper Mississippi River Cruise from St. Paul, MN to St. Louis, MO
Starting in St. Paul, MN; with stops in Red Wing, MN; Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO
2021 Sails: Sep 24, Oct 8, Oct 22, 2022: Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, Oct 21, 2023: Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Oct 6, Oct 20, More...
American Countess Cruises8 Night - Chicago (Ottawa) to St. Louis (Alton)
Starting in Chicago, IL; with stops in Ottawa, IL; Peoria, IL; Havana, IL; Hannibal, MO; Alton, IL; St. Louis (Alton)
2021 Sails: Sep 25, 2022: Aug 15, More...


St Louis River Cruises

Connecting cruisers with the best cruise prices on discount cruises since 2003. Privacy Policy

Cruise news from Cruise Compete, where you compare cruise prices to get the best cruise discounts and deals
Let our Virtual Cruise Advisor(TM) recommend the best cruises for you.