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St Louis River Cruises

River Cruises that visit North America: United States: Missouri: St Louis

River Cruises that depart from St Louis

Mississippi River Cruises

Click on a river cruise ship itinerary that visits St Louis (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just St Louis), please visit: Cruise Search or try our Virtual Cruise Advisor™.





American Harmony Cruises10 Night - Mississippi River Gateway Cruise New Orleans, Louisiana to St Louis, Missouri
Starting in New Orleans, with stops in Baton Rouge, Natchez, Vicksburg, Cruising the Mississippi River, Memphis, New Madrid, Paducah, Cruising the Ohio River, St Louis
2020 Sails: Nov 12, More...
American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from Nashville (Clarksville) to St. Louis
Starting in Nashville, TN; with stops in Clarksville, TN; Dover, TN; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO
2021 Sails: Apr 11, More...
American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from St. Louis to Cincinnati
Starting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Louisville, KY; Madison, IN; Cincinnati, OH
2021 Sails: Apr 18, More...
American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from Louisville to St. Louis
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2021 Sails: May 2, More...
American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from St. Louis to Memphis
Starting in St. Louis, MO; with stops in Alton, IL; Chester, IL; Cape Girardeau, MO; Paducah, KY; New Madrid, MO; Ashport Landing, TN; Memphis, TN
2021 Sails: May 9, Oct 3, More...
America Cruises10 Night - Mississippi River Gateway Cruise from New Orleans to St. Louis
Starting in New Orleans, LA; with stops in Baton Rouge, LA; Natchez, MS; Vicksburg, MS; Memphis, TN; New Madrid, MO; Paducah, KY; St. Louis, MO
2021 Sails: Jul 11, Aug 25, More...
American Queen Cruises8 Night - Ohio River and Tennessee River Cruise from Louisville to St. Louis
Starting in Louisville, KY; with stops in Brandenburg, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; Alton, IL
2021 Sails: Jul 11, More...
American Queen Cruises15 Night - Mississippi River Cruise from Minneapolis (Red Wing) to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Nottoway Plantation, New Orleans, LA
2021 Sails: Jul 25, More...
America Cruises7 Night - Upper Mississippi River from St. Paul, MN to St. Louis, MO
Starting in St. Paul, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Davenport, IA; Hannibal, MO; St. Louis, MO
2021 Sails: Jul 28, Sep 11, Sep 25, Oct 9, More...
Queen of the Mississippi Cruises10 Night - Mississippi River Gateway Cruise from St Louis, Missouri to New Orleans, Louisiana
Starting in St Louis, with stops in Cruising the Ohio River, Paducah, New Madrid, Memphis, Cruising the Mississippi River, Vicksburg, Natchez, Baton Rouge, New Orleans
2021 Sails: Jul 31, More...


St Louis River Cruises
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