CruiseCompete: Easily Compare Multiple Offers from Cruise Experts
Compare offers from multiple travel agencies
1
Find your cruise
& request quotes
2
Compare members only prices,
upgrades, cabin credits & more!
3
Contact your preferred agent
for questions or to book your cruise
Over 1 million members
St Louis River Cruises

River Cruises that visit North America: United States: Missouri: St Louis

River Cruises that depart from St Louis

See all Cruises that visit St Louis

Mississippi River Cruises

Click on a cruise ship itinerary that visits St Louis (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just St Louis), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name


American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from Nashville (Clarksville) to St. Louis
Starting in Nashville, TN; with stops in Clarksville, TN; Dover, TN; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO
2021 Sails: Apr 11, More...
American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from St. Louis to Cincinnati
Starting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Louisville, KY; Madison, IN; Cincinnati, OH
2021 Sails: Apr 18, More...
American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from Louisville to St. Louis
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2021 Sails: May 2, More...
American Duchess Cruises8 Night - Ohio River and Tennessee River Cruise from St. Louis to Memphis
Starting in St. Louis, MO; with stops in Alton, IL; Chester, IL; Cape Girardeau, MO; Paducah, KY; New Madrid, MO; Ashport Landing, TN; Memphis, TN
2021 Sails: May 9, Oct 3, More...
America Cruises10 Night - Mississippi River Gateway Cruise from New Orleans to St. Louis
Starting in New Orleans, LA; with stops in Baton Rouge, LA; Natchez, MS; Vicksburg, MS; Memphis, TN; New Madrid, MO; Paducah, KY; St. Louis, MO
2021 Sails: Jul 11, Aug 25, 2022: Jul 10, Aug 24, More...
American Queen Cruises8 Night - Ohio River and Tennessee River Cruise from Louisville to St. Louis
Starting in Louisville, KY; with stops in Brandenburg, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; Alton, IL
2021 Sails: Jul 11, More...
Queen of the Mississippi Cruises10 Night - Mississippi River Gateway Cruise from New Orleans, LA to St. Louis, MO
Starting in New Orleans, LA; with stops in Baton Rouge, LA; Natchez, MS; Vicksburg, MS; Memphis, TN; New Madrid, MO; Paducah, KY; St. Louis, MO
2021 Sails: Jul 17, 2022: Jul 27, More...
American Queen Cruises15 Night - Mississippi River Cruise from Minneapolis (Red Wing) to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Nottoway Plantation, New Orleans, LA
2021 Sails: Jul 25, More...
America Cruises7 Night - Upper Mississippi River from St. Paul, MN to St. Louis, MO
Starting in St. Paul, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO/Alton, IL
2021 Sails: Jul 28, Sep 11, Sep 25, Oct 9, 2022: Jul 27, Sep 10, Sep 24, Oct 8, More...
American Duchess Cruises15 Night - Mississippi River Cruise from Minneapolis (Red Wing) to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Nottoway Plantation, New Orleans, LA
2021 Sails: Aug 1, More...


St Louis River Cruises

Connecting cruisers with the best cruise prices on discount cruises since 2003. Privacy Policy

Cruise news from Cruise Compete, where you compare cruise prices to get the best cruise discounts and deals
Let our Virtual Cruise Advisor(TM) recommend the best cruises for you.