Santo Domingo Cruises
Cruises that visit Caribbean: Dominican Republic: Santo Domingo
Cruises that depart from Santo Domingo
6 Night - Western Caribbean from Fort De France
Starting in Martinique (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 3, More...7 Night - Western Caribbean from Fort De France
Starting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 9, More...7 Night - Western Caribbean from Pointe a Pitre
Starting in Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 10, More...7 Night - Western Caribbean from Fort De France
Starting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Catalina Island, Dominican Republic, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 16, More...7 Night - Western Caribbean from Pointe a Pitre
Starting in Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Catalina Island, Dominican Republic, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 17, More...7 Night - Western Caribbean from Fort De France
Starting in Martinique (Antilles), Guadeloupe (Antilles), St Maarten (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 23, More...7 Night - Western Caribbean from Pointe a Pitre
Starting in Guadeloupe (Antilles), St Maarten (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 24, More...8 Night - Western Caribbean from Fort De France
Starting in Martinique (Antilles), Guadeloupe (Antilles), St Lucia (Antilles), St Kitts (Antilles), St Maarten (Antilles), Santo Domingo, Dominican Republic, Antigua (Antilles), Martinique (Antilles)
2026 Sails: Dec 30, More...8 Night - Western Caribbean from Pointe a Pitre
Starting in Guadeloupe (Antilles), St Lucia (Antilles), St Kitts (Antilles), St Maarten (Antilles), Santo Domingo, Dominican Republic, Antigua (Antilles), Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 31, More...7 Night - Western Caribbean from Fort De France
Starting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, St Maarten (Antilles), Martinique (Antilles)
2027 Sails: Jan 7, Feb 25, More...
Cruises that visit Caribbean: Dominican Republic: Santo Domingo
Cruises that depart from Santo Domingo
Click on a cruise ship itinerary that visits Santo Domingo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santo Domingo), please visit: Cruise Search or try our Virtual Cruise Advisor™.
6 Night - Western Caribbean from Fort De FranceStarting in Martinique (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 3, More...
7 Night - Western Caribbean from Fort De FranceStarting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 9, More...
7 Night - Western Caribbean from Pointe a PitreStarting in Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 10, More...
7 Night - Western Caribbean from Fort De FranceStarting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Catalina Island, Dominican Republic, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 16, More...
7 Night - Western Caribbean from Pointe a PitreStarting in Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Catalina Island, Dominican Republic, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 17, More...
7 Night - Western Caribbean from Fort De FranceStarting in Martinique (Antilles), Guadeloupe (Antilles), St Maarten (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles)
2026 Sails: Dec 23, More...
7 Night - Western Caribbean from Pointe a PitreStarting in Guadeloupe (Antilles), St Maarten (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 24, More...
8 Night - Western Caribbean from Fort De FranceStarting in Martinique (Antilles), Guadeloupe (Antilles), St Lucia (Antilles), St Kitts (Antilles), St Maarten (Antilles), Santo Domingo, Dominican Republic, Antigua (Antilles), Martinique (Antilles)
2026 Sails: Dec 30, More...
8 Night - Western Caribbean from Pointe a PitreStarting in Guadeloupe (Antilles), St Lucia (Antilles), St Kitts (Antilles), St Maarten (Antilles), Santo Domingo, Dominican Republic, Antigua (Antilles), Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 31, More...
7 Night - Western Caribbean from Fort De FranceStarting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, St Maarten (Antilles), Martinique (Antilles)
2027 Sails: Jan 7, Feb 25, More...
