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Santo Domingo Cruises

Cruises that visit Caribbean: Dominican Republic: Santo Domingo

Cruises that depart from Santo Domingo

Click on a cruise ship itinerary that visits Santo Domingo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santo Domingo), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Costa Cruise Lines, Costa Serena
Costa Serena20 Night - Europe from Pointe a Pitre to Marseille
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Road Harbour (Tortola), Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre, Philipsburg, Santa Cruz de Tenerife, Tangier, Barcelona, Marseille
2028 Sails: Mar 3, More...
Costa Cruise Lines, Costa Serena
Costa Serena19 Night - Europe from Pointe a Pitre to Barcelona
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Road Harbour (Tortola), Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre, Philipsburg, Santa Cruz de Tenerife, Tangier, Barcelona
2028 Sails: Mar 3, More...
Silversea, Silver Nova
Silver Nova75 Night - Caribbean Roundtrip from Ft Lauderdale (Port Everglades)
Starting in Fort Lauderdale, San Juan, St Kitts, Gustavia, St Johns AG, Roseau, Soufriere, Bridgetown, Amazon River, Parintins, Manaus, Boca Da Valeria, Amazon River, Recife, Salvador De Bahia, Rio De Janeiro, Ilhabela, Brazil, Sao Francisco do Sul, Balneario Camboriu, Punta Del Este, Montevideo, Buenos Aires, Puerto Madryn, Port Stanley, Falkland Islands, Scenic Antarctic Peninsula, Ushuaia, Garibaldi Fjord and Glacier, Punta Arenas, Chilean Fjords, Puerto Montt, Valparaiso, Arica, Lima, Fuerte Amador, Panama Canal Transit, Cartagena CO, Santo Domingo, Fort Lauderdale
2029 Sails: Jan 13, More...
Silversea, Silver Nova
Silver Nova18 Night - Valparaiso to Fort Lauderdale
Starting in Valparaiso, Arica, Lima (Callao), Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Fort Lauderdale, Florida
2029 Sails: Mar 11, More...
Silversea, Silver Nova
Silver Nova32 Night - Cruise from Valparaiso to Barcelona
Starting in Valparaiso, Arica, Lima, Fuerte Amador, Panama Canal Transit, Cartagena CO, Santo Domingo, Fort Lauderdale, Royal Naval Dockyard, Valencia, Barcelona
2029 Sails: Mar 11, More...

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Santo Domingo Cruises