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Santo Domingo Cruises

Cruises that visit Caribbean: Dominican Republic: Santo Domingo

Cruises that depart from Santo Domingo

Click on a cruise ship itinerary that visits Santo Domingo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santo Domingo), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Costa Cruise Lines, Costa Serena
Costa Serena8 Night - Cruise Roundtrip from Pointe a Pitre
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Philipsburg, Road Harbour (Tortola), Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre
2027 Sails: Dec 30, More...
Costa Cruise Lines, Costa Serena
Costa Serena7 Night - Cruise Roundtrip from Pointe a Pitre
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Road Harbour (Tortola), Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre
2028 Sails: Jan 7, Jan 14, Jan 21, Jan 28, Feb 4, Feb 18, Feb 25, Mar 3, More...
Costa Cruise Lines, Costa Serena
Costa Serena7 Night - Cruise Roundtrip from Pointe a Pitre
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Philipsburg, Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre
2028 Sails: Feb 11, More...
Costa Cruise Lines, Costa Serena
Costa Serena21 Night - Europe from Pointe a Pitre to Savona
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Road Harbour (Tortola), Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre, Philipsburg, Santa Cruz de Tenerife, Tangier, Barcelona, Marseille, Savona
2028 Sails: Mar 3, More...
Costa Cruise Lines, Costa Serena
Costa Serena20 Night - Europe from Pointe a Pitre to Marseille
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Road Harbour (Tortola), Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre, Philipsburg, Santa Cruz de Tenerife, Tangier, Barcelona, Marseille
2028 Sails: Mar 3, More...
Costa Cruise Lines, Costa Serena
Costa Serena19 Night - Europe from Pointe a Pitre to Barcelona
Starting in Pointe-a-Pitre, Basseterre, Saint Kitts, Road Harbour (Tortola), Santo Domingo, St Johns AG, Antigua, Fort-de-France, Pointe-a-Pitre, Philipsburg, Santa Cruz de Tenerife, Tangier, Barcelona
2028 Sails: Mar 3, More...

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Santo Domingo Cruises