Santo Domingo Cruises
Cruises that visit Caribbean: Dominican Republic: Santo Domingo
Cruises that depart from Santo Domingo
14 Night - Star Collector : Rainforest Refuges of Panama & Costa Rica via the Panama Canal
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Apr 6, More...
39 Night - The Americas & Caribbean
Starting in Vancouver, Victoria CA, Canada, Astoria, Eureka, California, San Francisco, San Diego, California, Ensenada, Cabo San Lucas (Baja California Sur), Puerto Vallarta, Acajutla, San Juan del Sur, Puntarenas, Manta, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan, Marigot, St Martin, Roseau, Bridgetown, Castries, St Lucia, St Johns, Jost Van Dyke, British Virgin Islands, Samana, Grand Turk, New York
2026 Sails: Aug 17, More...32 Night - The Americas & Caribbean
Starting in San Diego, California, Ensenada, Cabo San Lucas (Baja California Sur), Puerto Vallarta, Acajutla, San Juan del Sur, Puntarenas, Manta, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan, Marigot, St Martin, Roseau, Bridgetown, Castries, St Lucia, St Johns, Jost Van Dyke, British Virgin Islands, Samana, Grand Turk, New York
2026 Sails: Aug 24, More...9 Night - The Americas & Caribbean
Starting in Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan
2026 Sails: Sep 5, More...26 Night - The Americas & Caribbean
Starting in Montreal, Quebec City, Iles-de-la-Madeleine, Quebec, Sydney NS, Nova Scotia, Halifax, Saint John NB, Portland ME, Boston, Newport, Rhode Island, New York, Royal Naval Dockyard, Santo Domingo, Samana, San Juan, Jost Van Dyke, British Virgin Islands, St Johns, Gustavia, St Barthelemy, St Thomas, Fort Lauderdale
2026 Sails: Oct 16, More...9 Night - The Americas & Caribbean
Starting in New York, Royal Naval Dockyard, Santo Domingo, Samana, San Juan
2026 Sails: Oct 26, More...
24 Night - Transatlantic from Hamburg
Starting in Hamburg, Germany, Amsterdam / Ijmuiden, Netherlands, Dover UK, England, Le Havre, France, Lisbon, Portugal, Cadiz, Spain, Las Palmas, Canary Islands, Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Guadeloupe (Antilles)
2026 Sails: Nov 8, More...8 Night - Western Caribbean from Fort De France
Starting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Guadeloupe (Antilles), Martinique (Antilles)
2026 Sails: Nov 25, More...6 Night - Western Caribbean from Pointe a Pitre
Starting in Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Guadeloupe (Antilles)
2026 Sails: Nov 26, More...8 Night - Western Caribbean from Pointe a Pitre
Starting in Guadeloupe (Antilles), Martinique (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 2, More...
Cruises that visit Caribbean: Dominican Republic: Santo Domingo
Cruises that depart from Santo Domingo
Click on a cruise ship itinerary that visits Santo Domingo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santo Domingo), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Star Collector : Rainforest Refuges of Panama & Costa Rica via the Panama CanalStarting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Apr 6, More...
39 Night - The Americas & CaribbeanStarting in Vancouver, Victoria CA, Canada, Astoria, Eureka, California, San Francisco, San Diego, California, Ensenada, Cabo San Lucas (Baja California Sur), Puerto Vallarta, Acajutla, San Juan del Sur, Puntarenas, Manta, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan, Marigot, St Martin, Roseau, Bridgetown, Castries, St Lucia, St Johns, Jost Van Dyke, British Virgin Islands, Samana, Grand Turk, New York
2026 Sails: Aug 17, More...
32 Night - The Americas & CaribbeanStarting in San Diego, California, Ensenada, Cabo San Lucas (Baja California Sur), Puerto Vallarta, Acajutla, San Juan del Sur, Puntarenas, Manta, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan, Marigot, St Martin, Roseau, Bridgetown, Castries, St Lucia, St Johns, Jost Van Dyke, British Virgin Islands, Samana, Grand Turk, New York
2026 Sails: Aug 24, More...
9 Night - The Americas & CaribbeanStarting in Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan
2026 Sails: Sep 5, More...
26 Night - The Americas & CaribbeanStarting in Montreal, Quebec City, Iles-de-la-Madeleine, Quebec, Sydney NS, Nova Scotia, Halifax, Saint John NB, Portland ME, Boston, Newport, Rhode Island, New York, Royal Naval Dockyard, Santo Domingo, Samana, San Juan, Jost Van Dyke, British Virgin Islands, St Johns, Gustavia, St Barthelemy, St Thomas, Fort Lauderdale
2026 Sails: Oct 16, More...
9 Night - The Americas & CaribbeanStarting in New York, Royal Naval Dockyard, Santo Domingo, Samana, San Juan
2026 Sails: Oct 26, More...
24 Night - Transatlantic from HamburgStarting in Hamburg, Germany, Amsterdam / Ijmuiden, Netherlands, Dover UK, England, Le Havre, France, Lisbon, Portugal, Cadiz, Spain, Las Palmas, Canary Islands, Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Guadeloupe (Antilles)
2026 Sails: Nov 8, More...
8 Night - Western Caribbean from Fort De FranceStarting in Martinique (Antilles), Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Guadeloupe (Antilles), Martinique (Antilles)
2026 Sails: Nov 25, More...
6 Night - Western Caribbean from Pointe a PitreStarting in Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Guadeloupe (Antilles)
2026 Sails: Nov 26, More...
8 Night - Western Caribbean from Pointe a PitreStarting in Guadeloupe (Antilles), Martinique (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Dec 2, More...
