Santa Cruz Island Cruises
Cruises that visit South America: Ecuador: Galapagos Islands: Santa Cruz Island
Cruises that depart from Santa Cruz Island
See all River Cruises that visit Santa Cruz Island
10 Night - Galapagos Islands - Nine of the Best Isles
Starting in Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Fernandina, Puerto Ayora, Isla Santa Cruz, Post Office Bay, Champion Islet, Punta Cormorant, Seymour, Las Bachas, Santa Cruz Island, Buccaneer Cove, Puerto Egas, Rabida Island, Bartolome Island, Prince Philip Steps, Genovesa Island, Darwin Bay, Genovesa Island, Itabaca Channel, Seymour, Baltra Airport (Galapagos)
2026 Sails: Oct 27, Nov 10, Nov 24, Dec 8, More...
6 Night - Galapagos Islands - Iconic Wildlife & Sublime Scenery / Western Route
Starting in Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Fernandina, Puerto Ayora, Isla Santa Cruz, Post Office Bay, Champion Islet, Punta Cormorant, Seymour, Baltra Airport (Galapagos)
2026 Sails: Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, More...
16 Night - Galapagos Inner Loop & Machu Picchu
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Egas Port, Santiago Island, Rabida Island, Elizabeth Bay, Tagus Cove, Isabela Island, Sullivan Bay (Santiago Island), Bartolome Island, Las Bachas, Santa Cruz Island, Daphne Major / Cruising, North Seymour Island, Puerto Baquerizo Moreno, San Cristobal Island, Punta Pitt, San Cristobal Island, Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation Fly to Quito, Lima, Peru, Fly from Lima to Cuzco and the Sacred Valley, Peru, The Sacred Valley, Sacred Valley and Machu Picchu, Cuzco, Peru, Fly to Lima, Peru / Depart Lima, Peru, Depart Lima, Peru
2026 Sails: Dec 18, 2027: Jan 1, Feb 26, Mar 26, Apr 9, Apr 23, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, 2028: Jan 14, Jan 28, More...
13 Night - Galapagos Islands - in Darwin's Footsteps Plus Machu Picchu
Starting in Lima Airport, Lima, Lima Airport, Cusco Airport, Quito Airport, Quito, Quito Airport, Seymour, Mosquera, Punta Pitt, San Cristobal Island, Puerto Baquerizo Moreno, Santa Fe, South Plaza Island, Puerto Ayora, Isla Santa Cruz, Punta Suarez, Espanola Island, Bahia Gardner, Espanola, Islote Eden, Seymour Norte, Seymour, Baltra Airport (Galapagos)
2026 Sails: Dec 25, 2027: Jan 8, Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, Oct 29, Nov 12, Nov 26, Dec 10, More...
8 Night - In Darwin's Footsteps (Eastern Route)
Starting in Quito Airport, Quito, Quito Airport, Seymour, Mosquera, Punta Pitt, San Cristobal Island, Puerto Baquerizo Moreno, Santa Fe, South Plaza Island, Puerto Ayora, Isla Santa Cruz, Punta Suarez, Espanola Island, Bahia Gardner, Espanola, Islote Eden, Seymour Norte, Seymour, Baltra Airport (Galapagos)
2026 Sails: Dec 30, 2027: Jan 13, Jan 27, Feb 10, Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Nov 3, Nov 17, Dec 1, Dec 15, More...
15 Night - Galapagos Islands - Nine of the Best Isles Plus Machu Picchu
Starting in Lima Airport, Lima, Lima Airport, Cusco Airport, Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Punta Espinoza, Fernandina Island, Puerto Ayora, Isla Santa Cruz, Baroness Tower, Floreana Island, Punta Cormorant, Seymour, Las Bachas, Santa Cruz Island, Buccaneer Cove, Puerto Egas, Rabida Island, Bartolome Island, Prince Philip Steps, Genovesa Island, Darwin Bay, Genovesa Island, Itabaca Channel, Seymour, Baltra Airport (Galapagos)
2026 Sails: Dec 31, 2027: Jan 14, Jan 28, Feb 11, Feb 25, Mar 11, Mar 25, Apr 8, Apr 22, May 6, May 20, Jun 3, Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Oct 21, Nov 4, Nov 18, Dec 2, Dec 16, More...
10 Night - Galapagos Islands - Nine of the Best Isles
Starting in Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Punta Espinoza, Fernandina Island, Puerto Ayora, Isla Santa Cruz, Baroness Tower, Floreana Island, Punta Cormorant, Seymour, Las Bachas, Santa Cruz Island, Buccaneer Cove, Puerto Egas, Rabida Island, Bartolome Island, Prince Philip Steps, Genovesa Island, Darwin Bay, Genovesa Island, Itabaca Channel, Seymour, Baltra Airport (Galapagos)
2027 Sails: Jan 5, Jan 19, Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, Aug 17, Aug 31, Sep 14, Oct 26, Nov 9, Nov 23, Dec 7, Dec 21, More...
16 Night - Galapagos Outer Loop and Machu Picchu
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Gardner Bay (Espanola), Punta Suarez, Cormorant Point (Floreana), Post Office Bay, Floreana Island, Moreno Point, Isabela Island, Urbina Bay, Espinoza Point, Vicente Roca Point, South Plaza (Santa Cruz Island), Daphne Major / Cruising, Dragon Hill (Santa Cruz Island), Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation Fly to Quito, Lima, Peru, Fly from Lima to Cuzco and the Sacred Valley, Peru, The Sacred Valley, Sacred Valley and Machu Picchu, Cuzco, Peru, Fly to Lima, Peru / Depart Lima, Peru, Depart Lima, Peru
2027 Sails: Feb 5, Mar 5, Mar 19, Apr 16, Apr 30, May 14, Jun 11, Jun 25, Jul 9, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, 2028: Jan 7, Jan 21, Feb 4, Feb 18, More...
11 Night - Quito & Galapagos Outer Loop
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Gardner Bay (Espanola), Punta Suarez, Cormorant Point (Floreana), Post Office Bay, Floreana Island, Moreno Point, Isabela Island, Urbina Bay, Espinoza Point, Vicente Roca Point, South Plaza (Santa Cruz Island), Daphne Major / Cruising, Dragon Hill (Santa Cruz Island), Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation, Quito, Ecuador
2027 Sails: Feb 5, Mar 5, Mar 19, Apr 16, Apr 30, May 14, Jun 11, Jun 25, Jul 9, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, More...
10 Night - Quito & Galapagos Outer Loop
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Gardner Bay (Espanola), Punta Suarez, Cormorant Point (Floreana), Post Office Bay, Floreana Island, Moreno Point, Isabela Island, Urbina Bay, Espinoza Point, Vicente Roca Point, South Plaza (Santa Cruz Island), Daphne Major / Cruising, Dragon Hill (Santa Cruz Island), Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation, Quito, Ecuador
2027 Sails: Feb 5, Mar 5, Mar 19, Apr 16, Apr 30, May 14, Jun 11, Jun 25, Jul 9, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, 2028: Jan 7, Jan 21, Feb 4, Feb 18, More...
Cruises that visit South America: Ecuador: Galapagos Islands: Santa Cruz Island
Cruises that depart from Santa Cruz Island
See all River Cruises that visit Santa Cruz Island
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10 Night - Galapagos Islands - Nine of the Best IslesStarting in Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Fernandina, Puerto Ayora, Isla Santa Cruz, Post Office Bay, Champion Islet, Punta Cormorant, Seymour, Las Bachas, Santa Cruz Island, Buccaneer Cove, Puerto Egas, Rabida Island, Bartolome Island, Prince Philip Steps, Genovesa Island, Darwin Bay, Genovesa Island, Itabaca Channel, Seymour, Baltra Airport (Galapagos)
2026 Sails: Oct 27, Nov 10, Nov 24, Dec 8, More...
6 Night - Galapagos Islands - Iconic Wildlife & Sublime Scenery / Western RouteStarting in Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Fernandina, Puerto Ayora, Isla Santa Cruz, Post Office Bay, Champion Islet, Punta Cormorant, Seymour, Baltra Airport (Galapagos)
2026 Sails: Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, More...
16 Night - Galapagos Inner Loop & Machu PicchuStarting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Egas Port, Santiago Island, Rabida Island, Elizabeth Bay, Tagus Cove, Isabela Island, Sullivan Bay (Santiago Island), Bartolome Island, Las Bachas, Santa Cruz Island, Daphne Major / Cruising, North Seymour Island, Puerto Baquerizo Moreno, San Cristobal Island, Punta Pitt, San Cristobal Island, Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation Fly to Quito, Lima, Peru, Fly from Lima to Cuzco and the Sacred Valley, Peru, The Sacred Valley, Sacred Valley and Machu Picchu, Cuzco, Peru, Fly to Lima, Peru / Depart Lima, Peru, Depart Lima, Peru
2026 Sails: Dec 18, 2027: Jan 1, Feb 26, Mar 26, Apr 9, Apr 23, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, 2028: Jan 14, Jan 28, More...
13 Night - Galapagos Islands - in Darwin's Footsteps Plus Machu PicchuStarting in Lima Airport, Lima, Lima Airport, Cusco Airport, Quito Airport, Quito, Quito Airport, Seymour, Mosquera, Punta Pitt, San Cristobal Island, Puerto Baquerizo Moreno, Santa Fe, South Plaza Island, Puerto Ayora, Isla Santa Cruz, Punta Suarez, Espanola Island, Bahia Gardner, Espanola, Islote Eden, Seymour Norte, Seymour, Baltra Airport (Galapagos)
2026 Sails: Dec 25, 2027: Jan 8, Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, Oct 29, Nov 12, Nov 26, Dec 10, More...
Deal link -> Special
8 Night - In Darwin's Footsteps (Eastern Route)Starting in Quito Airport, Quito, Quito Airport, Seymour, Mosquera, Punta Pitt, San Cristobal Island, Puerto Baquerizo Moreno, Santa Fe, South Plaza Island, Puerto Ayora, Isla Santa Cruz, Punta Suarez, Espanola Island, Bahia Gardner, Espanola, Islote Eden, Seymour Norte, Seymour, Baltra Airport (Galapagos)
2026 Sails: Dec 30, 2027: Jan 13, Jan 27, Feb 10, Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Nov 3, Nov 17, Dec 1, Dec 15, More...
15 Night - Galapagos Islands - Nine of the Best Isles Plus Machu PicchuStarting in Lima Airport, Lima, Lima Airport, Cusco Airport, Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Punta Espinoza, Fernandina Island, Puerto Ayora, Isla Santa Cruz, Baroness Tower, Floreana Island, Punta Cormorant, Seymour, Las Bachas, Santa Cruz Island, Buccaneer Cove, Puerto Egas, Rabida Island, Bartolome Island, Prince Philip Steps, Genovesa Island, Darwin Bay, Genovesa Island, Itabaca Channel, Seymour, Baltra Airport (Galapagos)
2026 Sails: Dec 31, 2027: Jan 14, Jan 28, Feb 11, Feb 25, Mar 11, Mar 25, Apr 8, Apr 22, May 6, May 20, Jun 3, Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Oct 21, Nov 4, Nov 18, Dec 2, Dec 16, More...
10 Night - Galapagos Islands - Nine of the Best IslesStarting in Quito Airport, Quito, Quito Airport, Seymour, Dragon Hill, Punta Vicente Roca, Punta Espinoza, Fernandina Island, Puerto Ayora, Isla Santa Cruz, Baroness Tower, Floreana Island, Punta Cormorant, Seymour, Las Bachas, Santa Cruz Island, Buccaneer Cove, Puerto Egas, Rabida Island, Bartolome Island, Prince Philip Steps, Genovesa Island, Darwin Bay, Genovesa Island, Itabaca Channel, Seymour, Baltra Airport (Galapagos)
2027 Sails: Jan 5, Jan 19, Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, Aug 17, Aug 31, Sep 14, Oct 26, Nov 9, Nov 23, Dec 7, Dec 21, More...
16 Night - Galapagos Outer Loop and Machu PicchuStarting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Gardner Bay (Espanola), Punta Suarez, Cormorant Point (Floreana), Post Office Bay, Floreana Island, Moreno Point, Isabela Island, Urbina Bay, Espinoza Point, Vicente Roca Point, South Plaza (Santa Cruz Island), Daphne Major / Cruising, Dragon Hill (Santa Cruz Island), Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation Fly to Quito, Lima, Peru, Fly from Lima to Cuzco and the Sacred Valley, Peru, The Sacred Valley, Sacred Valley and Machu Picchu, Cuzco, Peru, Fly to Lima, Peru / Depart Lima, Peru, Depart Lima, Peru
2027 Sails: Feb 5, Mar 5, Mar 19, Apr 16, Apr 30, May 14, Jun 11, Jun 25, Jul 9, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, 2028: Jan 7, Jan 21, Feb 4, Feb 18, More...
11 Night - Quito & Galapagos Outer LoopStarting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Gardner Bay (Espanola), Punta Suarez, Cormorant Point (Floreana), Post Office Bay, Floreana Island, Moreno Point, Isabela Island, Urbina Bay, Espinoza Point, Vicente Roca Point, South Plaza (Santa Cruz Island), Daphne Major / Cruising, Dragon Hill (Santa Cruz Island), Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation, Quito, Ecuador
2027 Sails: Feb 5, Mar 5, Mar 19, Apr 16, Apr 30, May 14, Jun 11, Jun 25, Jul 9, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, More...
10 Night - Quito & Galapagos Outer LoopStarting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Gardner Bay (Espanola), Punta Suarez, Cormorant Point (Floreana), Post Office Bay, Floreana Island, Moreno Point, Isabela Island, Urbina Bay, Espinoza Point, Vicente Roca Point, South Plaza (Santa Cruz Island), Daphne Major / Cruising, Dragon Hill (Santa Cruz Island), Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation, Quito, Ecuador
2027 Sails: Feb 5, Mar 5, Mar 19, Apr 16, Apr 30, May 14, Jun 11, Jun 25, Jul 9, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, 2028: Jan 7, Jan 21, Feb 4, Feb 18, More...