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Santa Cruz Island Cruises

Cruises that visit South America: Ecuador: Galapagos Islands: Santa Cruz Island

Cruises that depart from Santa Cruz Island

See all River Cruises that visit Santa Cruz Island

Click on a cruise ship itinerary that visits Santa Cruz Island (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santa Cruz Island), please visit: Cruise Search or try our Virtual Cruise Advisor™.


La Pinta Cruises4 Night - Northern Galapagos Islands Roundtrip from Baltra Island
Starting in Baltra Island, Santa Cruz Island, Eden Islet, Chinese Hat Islet, Bartolome Island, Sullivan Bay (Santiago Island), Punta Suarez, Gardner Bay, Baltra Island
2025 Sails: Nov 17, Dec 1, Dec 15, Dec 29, More...
Isabela II Cruises4 Night - Western Galapagos Islands Roundtrip from Baltra Island
Starting in Santa Cruz Island, Puerto Ayora / Charles Darwin Research Station, Bartolome Island, Sullivan Bay (Santiago Island), Dragon Hill (Santa Cruz Island), Buccaneer Cove (Santiago Island), Punta Vicente Roca (Isabela Island), Punta Espinoza (Fernandina Island), Baltra Island
2025 Sails: Nov 20, Nov 21, Dec 4, Dec 18, More...
Isabela II Cruises4 Night - Western Galapagos Islands Roundtrip from Baltra Island
Starting in Baltra Island / Santa Cruz Island, Bartolome Island / Santiago Island, Santa Cruz Island / Santiago Island, Isabela Island / Fernandina Island, Baltra Island
2025 Sails: Nov 20, Dec 4, Dec 18, More...
La Pinta Cruises6 Night - Western Galapagos Islands Roundtrip from Baltra Island
Starting in Baltra Island / North Seymour Island, Isabela Island / Fernandina Island, Urbina Bay / Tagus Cove, Rabida, Santa Cruz Island, Floreana Island, Baltra Island
2025 Sails: Nov 21, Dec 5, Dec 19, More...
Isabela II Cruises6 Night - Southeastern Galapagos Islands Roundtrip from Baltra Island
Starting in Santa Cruz Island, Las Bachas, Santa Cruz Island, Punta Pitt (San Cristobal), Cerro Colorado (San Cristobal Island), Gardner Bay (Espanola Island), Punta Suarez (Espanola Island), Cormorant Point (Floreana Island), Post Office Bay / Baroness Cove (Floreana Island), Punta Moreno (Isabela Island), Punta Mangle (Fernandina Island), Eden Islet, North Seymour Island, Baltra Island
2025 Sails: Nov 28, Dec 12, Dec 26, More...
Celebrity Flora Cruise Tours10 Night - Quito & Galapagos Inner Loop
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Egas Port, Santiago Island, Rabida Island, Elizabeth Bay, Tagus Cove, Isabela Island, Sullivan Bay (Santiago Island), Bartolome Island, Las Bachas, Santa Cruz Island, Daphne Major / Cruising, North Seymour Island, Puerto Baquerizo Moreno, San Cristobal Island, Punta Pitt, San Cristobal Island, Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation, Quito, Ecuador
2025 Sails: Dec 5, More...
Celebrity Flora Cruise Tours11 Night - Quito & Galapagos Inner Loop
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Egas Port, Santiago Island, Rabida Island, Elizabeth Bay, Tagus Cove, Isabela Island, Sullivan Bay (Santiago Island), Bartolome Island, Las Bachas, Santa Cruz Island, Daphne Major / Cruising, North Seymour Island, Puerto Baquerizo Moreno, San Cristobal Island, Punta Pitt, San Cristobal Island, Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation, Quito, Ecuador
2025 Sails: Dec 5, More...
Celebrity Flora Cruises7 Night - Galapagos Inner Loop Cruise
Starting in Baltra (Galapagos), Egas Port, Rabida (Galapagos), Elizabeth Bay (Isabela), Tagus Cove (Isabela), Sullivan Bay (Santiago), Bartolome Island, Las Bachas, Santa Cruz Island, Daphne Island, North Seymour Island, Puerto Baquerizo (Cristobal), Punta Pitt (San Cristobal), Puerto Ayora, Santa Cruz Island, Baltra (Galapagos)
2025 Sails: Dec 7, 2026: Jan 18, Feb 1, Feb 15, Mar 1, Apr 12, Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, Nov 8, Nov 22, Dec 6, Dec 20, 2027: Jan 3, Jan 17, Jan 31, More...
Isabela II Cruises4 Night - Northwestern Islands of Fire Adventure Roundtrip from Baltra Island & Santa Cruz Island
Starting in Baltra Island and Santa Cruz Island, Bartolome Island and Santiago Island, Santa Cruz Island and Santiago Island, Isabela Island and Fernandina Island, Baltra Island
2026 Sails: Jan 1, Jan 15, Jan 29, Feb 12, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, More...
La Pinta Cruises6 Night - Southwestern Darwin's Legacy Southwestern Roundtrip from Baltra & North Seymour Islands
Starting in Baltra Island / North Seymour, Isabela and Fernandina Islands, Urbina Bay and Tagus Cove, Rabida and Santa Cruz Islands, Santa Cruz Island, Floreana Island, Baltra Island
2026 Sails: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, Nov 6, Nov 20, More...


Santa Cruz Island Cruises