Panama City Cruises
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose, Santa Elena (Monteverde), Monteverde Hotel, La Fortuna (Arenal), Arenal Hotel, La Fortuna (Arenal), Arenal Hotel, San Jose, Costa Rica Marriott Hotel Hacienda Belen or Similar, Juan Santamaria International
2027 Sails: Jan 5, Jan 19, Feb 2, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 6, Jan 20, Mar 17, Apr 28, May 12, May 26, Jun 23, Sep 1, Sep 15, Sep 29, Nov 10, Nov 24, Dec 8, Dec 22, More...
10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 6, Jan 20, Feb 3, Feb 17, Mar 17, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, More...
23 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Hilo, Hawaii, Kahului, Hawaii, Honolulu, Hawaii
2027 Sails: Jan 6, More...15 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Jan 6, More...129 Night - Wc Grand Circle Pacific - Ft. Lauderdale to Los Angeles
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Hilo, Hawaii, Kahului, Hawaii, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Pago Pago, American Samoa, Cross International Date Line, Suva, Fiji, Dravuni Island, Fiji, Port Vila, Vanuatu, Luganville, Vanuatu, Rabaul, Papua New Guinea, Kiriwina Island, Papua New Guinea, Alotau (Milne Bay), Papua New Guinea, Cairns, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Auckland, New Zealand, Tauranga, New Zealand, Christchurch (Lyttelton), New Zealand, Dunedin (Port Chalmers), New Zealand, Fiordland National Park (Scenic Cruising), Hobart, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Kimberley Coast (Scenic Cruising), Australia, Darwin, Australia, Bali (Benoa), Indonesia, Lombok, Indonesia, Singapore, Phuket, Thailand, Langkawi, Malaysia, Penang, Malaysia, Kuala Lumpur (Port Kelang), Malaysia, Ho Chi Minh City (Phu My), Vietnam, Cam Ranh (Nha Trang), Vietnam, Halong Bay / Hanoi (Cai Lan), Vietnam, Hong Kong, Taipei (Keelung), Miyakojima, Japan, Kagoshima, Japan, Kochi, Japan, Osaka (for Kyoto), Japan, Tokyo, Japan, Miyako, Japan, Kushiro, Japan, Cross International Date Line, Anchorage (Whittier), Alaska, College Fjord (Scenic Cruising), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Sitka, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada, Los Angeles, California
2027 Sails: Jan 6, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla, Panama City
2027 Sails: Jan 8, Feb 19, Mar 5, Apr 2, Apr 16, May 14, May 28, Jun 11, Aug 20, Sep 3, Sep 17, Oct 1, Oct 29, Nov 12, Nov 26, Dec 10, More...10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 9, Jan 23, Mar 20, May 1, May 15, May 29, Jun 26, Sep 4, Sep 18, Oct 2, Nov 13, Nov 27, Dec 11, Dec 25, More...
82 Night - South America Discovery
Starting in Southampton, England, UK, Hamilton, Bermuda, Port Canaveral, FL, Fort Lauderdale, FL, Grand Turk, Turks and Caicos Islands, Bridgetown, Barbados, Fortaleza, Brazil, Salvador, Brazil, Buzios, Brazil, Rio De Janeiro, Brazil, Santos (tours to Sao Paulo), Brazil, Montevideo, Uruguay, Buenos Aires, Argentina, Puerto Madryn, Argentina, Ushuaia, Argentina, Cape Horn, Chile (Sail by), Punta Arenas, Chile, Amalia Glacier, Chile (Scenic Cruising), PIO X Glacier, Chile (Scenic Cruising), Puerto Montt, Chile, San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL, Port Canaveral, FL, Praia da Vitoria, Azores, Portugal, Southampton, England, UK
2027 Sails: Jan 10, More...
141 Night - World of Splendor
Starting in Miami, Cruising the Caribbean Sea, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Roatan, Cruising the Caribbean Sea, George Town, Ocho Rios, Jamaica, Cruising the Caribbean Sea, Puerto Limon, Cruising the Caribbean Sea, Cartagena CO, Panama Canal Transit, Panama City, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Acajutla, Puerto Quetzal, Cruising the Pacific Ocean, Puerto Vallarta, Cabo San Lucas, Cruising the Pacific Ocean, Los Angeles, Cruising the Pacific Ocean, Kahului, Honolulu, Hilo, Cruising the Pacific Ocean, Bora Bora, Moorea, Papeete (Tahiti), Moorea, Huahine, Raiatea, Bora Bora, Cruising the South Pacific, Pago Pago, Cross the International Date Line, Apia, Cruising the South Pacific, Suva, Lautoka, Cruising the South Pacific, Mystery Island, Lifou Island, Noumea, Cruising the Coral Sea, Cruising the Tasman Sea, Sydney AU, Cruising the Tasman Sea, Cruising the Coral Sea, Townsville, Cairns, Cooktown, Cruising the Coral Sea, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Komodo, Bali (Benoa), Surabaya, Semarang (Java), Cruising the Java Sea, Singapore, Kuala Lumpur (Port Klang), Penang, Phuket, Cruising the Andaman Sea, Cruising the Bay of Bengal, Colombo, Cruising the Laccadive Sea, Male, Cruising the Laccadive Sea, Cochin (Kochi), Mangalore, Goa (Mormugao), Mumbai (Bombay), Cruising the Arabian Sea, Muscat, Dubai, Doha, Abu Dhabi, Cruising the Gulf of Oman, Cruising the Arabian Sea, Salalah, Cruising the Arabian Sea, Cruising the Gulf of Aden, Cruising the Red Sea, Jeddah, Cruising the Red Sea, Luxor (Safaga), Aqaba, Suez Canal (Transit), Jerusalem (Haifa), Limassol, Rhodes, Kusadasi, Athens (Piraeus), Cruising the Mediterranean Sea, Sorrento / Capri, Rome (Civitavecchia), Cruising the Mediterranean Sea, Barcelona (Tarragona), Alicante, Malaga, Casablanca, Cruising the Atlantic Ocean, Halifax, Cruising the Atlantic Ocean, New York
2027 Sails: Jan 11, More...
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
Click on a cruise ship itinerary that visits Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.
11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise TourStarting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose, Santa Elena (Monteverde), Monteverde Hotel, La Fortuna (Arenal), Arenal Hotel, La Fortuna (Arenal), Arenal Hotel, San Jose, Costa Rica Marriott Hotel Hacienda Belen or Similar, Juan Santamaria International
2027 Sails: Jan 5, Jan 19, Feb 2, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 6, Jan 20, Mar 17, Apr 28, May 12, May 26, Jun 23, Sep 1, Sep 15, Sep 29, Nov 10, Nov 24, Dec 8, Dec 22, More...
10 Night - Magic of Colombia with Panama Post CruiseStarting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 6, Jan 20, Feb 3, Feb 17, Mar 17, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, More...
23 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Hilo, Hawaii, Kahului, Hawaii, Honolulu, Hawaii
2027 Sails: Jan 6, More...
15 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Jan 6, More...
129 Night - Wc Grand Circle Pacific - Ft. Lauderdale to Los AngelesStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Hilo, Hawaii, Kahului, Hawaii, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Pago Pago, American Samoa, Cross International Date Line, Suva, Fiji, Dravuni Island, Fiji, Port Vila, Vanuatu, Luganville, Vanuatu, Rabaul, Papua New Guinea, Kiriwina Island, Papua New Guinea, Alotau (Milne Bay), Papua New Guinea, Cairns, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Auckland, New Zealand, Tauranga, New Zealand, Christchurch (Lyttelton), New Zealand, Dunedin (Port Chalmers), New Zealand, Fiordland National Park (Scenic Cruising), Hobart, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Kimberley Coast (Scenic Cruising), Australia, Darwin, Australia, Bali (Benoa), Indonesia, Lombok, Indonesia, Singapore, Phuket, Thailand, Langkawi, Malaysia, Penang, Malaysia, Kuala Lumpur (Port Kelang), Malaysia, Ho Chi Minh City (Phu My), Vietnam, Cam Ranh (Nha Trang), Vietnam, Halong Bay / Hanoi (Cai Lan), Vietnam, Hong Kong, Taipei (Keelung), Miyakojima, Japan, Kagoshima, Japan, Kochi, Japan, Osaka (for Kyoto), Japan, Tokyo, Japan, Miyako, Japan, Kushiro, Japan, Cross International Date Line, Anchorage (Whittier), Alaska, College Fjord (Scenic Cruising), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Sitka, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada, Los Angeles, California
2027 Sails: Jan 6, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla, Panama City
2027 Sails: Jan 8, Feb 19, Mar 5, Apr 2, Apr 16, May 14, May 28, Jun 11, Aug 20, Sep 3, Sep 17, Oct 1, Oct 29, Nov 12, Nov 26, Dec 10, More...
10 Night - Magic of Colombia with Panama Post CruiseStarting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 9, Jan 23, Mar 20, May 1, May 15, May 29, Jun 26, Sep 4, Sep 18, Oct 2, Nov 13, Nov 27, Dec 11, Dec 25, More...
82 Night - South America DiscoveryStarting in Southampton, England, UK, Hamilton, Bermuda, Port Canaveral, FL, Fort Lauderdale, FL, Grand Turk, Turks and Caicos Islands, Bridgetown, Barbados, Fortaleza, Brazil, Salvador, Brazil, Buzios, Brazil, Rio De Janeiro, Brazil, Santos (tours to Sao Paulo), Brazil, Montevideo, Uruguay, Buenos Aires, Argentina, Puerto Madryn, Argentina, Ushuaia, Argentina, Cape Horn, Chile (Sail by), Punta Arenas, Chile, Amalia Glacier, Chile (Scenic Cruising), PIO X Glacier, Chile (Scenic Cruising), Puerto Montt, Chile, San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL, Port Canaveral, FL, Praia da Vitoria, Azores, Portugal, Southampton, England, UK
2027 Sails: Jan 10, More...
141 Night - World of SplendorStarting in Miami, Cruising the Caribbean Sea, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Roatan, Cruising the Caribbean Sea, George Town, Ocho Rios, Jamaica, Cruising the Caribbean Sea, Puerto Limon, Cruising the Caribbean Sea, Cartagena CO, Panama Canal Transit, Panama City, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Acajutla, Puerto Quetzal, Cruising the Pacific Ocean, Puerto Vallarta, Cabo San Lucas, Cruising the Pacific Ocean, Los Angeles, Cruising the Pacific Ocean, Kahului, Honolulu, Hilo, Cruising the Pacific Ocean, Bora Bora, Moorea, Papeete (Tahiti), Moorea, Huahine, Raiatea, Bora Bora, Cruising the South Pacific, Pago Pago, Cross the International Date Line, Apia, Cruising the South Pacific, Suva, Lautoka, Cruising the South Pacific, Mystery Island, Lifou Island, Noumea, Cruising the Coral Sea, Cruising the Tasman Sea, Sydney AU, Cruising the Tasman Sea, Cruising the Coral Sea, Townsville, Cairns, Cooktown, Cruising the Coral Sea, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Komodo, Bali (Benoa), Surabaya, Semarang (Java), Cruising the Java Sea, Singapore, Kuala Lumpur (Port Klang), Penang, Phuket, Cruising the Andaman Sea, Cruising the Bay of Bengal, Colombo, Cruising the Laccadive Sea, Male, Cruising the Laccadive Sea, Cochin (Kochi), Mangalore, Goa (Mormugao), Mumbai (Bombay), Cruising the Arabian Sea, Muscat, Dubai, Doha, Abu Dhabi, Cruising the Gulf of Oman, Cruising the Arabian Sea, Salalah, Cruising the Arabian Sea, Cruising the Gulf of Aden, Cruising the Red Sea, Jeddah, Cruising the Red Sea, Luxor (Safaga), Aqaba, Suez Canal (Transit), Jerusalem (Haifa), Limassol, Rhodes, Kusadasi, Athens (Piraeus), Cruising the Mediterranean Sea, Sorrento / Capri, Rome (Civitavecchia), Cruising the Mediterranean Sea, Barcelona (Tarragona), Alicante, Malaga, Casablanca, Cruising the Atlantic Ocean, Halifax, Cruising the Atlantic Ocean, New York
2027 Sails: Jan 11, More...
