Panama City Cruises
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
36 Night - San Antonio to Hamburg
Starting in San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Manta, Ecuador, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL, Port Canaveral, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK, Zeebrugge (tours to Bruges), Belgium, Hamburg, Germany
2027 Sails: Feb 28, More...33 Night - San Antonio to Southampton
Starting in San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Manta, Ecuador, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL, Port Canaveral, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2027 Sails: Feb 28, More...19 Night - San Antonio to Fort Lauderdale
Starting in San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Manta, Ecuador, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL
2027 Sails: Feb 28, More...
20 Night - Panama Canal Navigator
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Port Antonio, Great Stirrup Cay, Miami
2027 Sails: Mar 5, More...10 Night - Panama Potpourri
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City
2027 Sails: Mar 5, More...
18 Night - Valparaiso to Miami
Starting in Valparaiso, Arica, Lima (Callao), Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cozumel, Quintana Roo, Miami, Fl
2027 Sails: Mar 5, More...
19 Night - Southern America & Panama Canal Cruise : Lima, Panama City & Cozumel
Starting in San Antonio Cl, Coquimbo, Iquique, Arica, Pisco, Callao (Lima), Panama City (Fuerte Amador), Panama Canal (Cruising), Puerto Limon, Isla San Andres, Cozumel, Mexico, Miami, Florida
2027 Sails: Mar 10, More...
16 Night - Machu Picchu & Mayan Ruins
Starting in Lima (Callao), Salaverry, Cruising the Pacific Ocean, Guayaquil, Manta, Cruising the Pacific Ocean, Golfito, Panama City, Panama Canal Transit, Puerto Limon, Cruising the Caribbean Sea, Roatan, Harvest Caye, Costa Maya, Mexico, Cruising the Straits of Florida, Miami
2027 Sails: Mar 10, More...10 Night - Panama & Pristine Isles
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Port Antonio, Great Stirrup Cay, Miami
2027 Sails: Mar 15, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Ensenada, Mexico, Los Angeles, California
2027 Sails: Mar 18, More...
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
Click on a cruise ship itinerary that visits Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.
36 Night - San Antonio to HamburgStarting in San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Manta, Ecuador, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL, Port Canaveral, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK, Zeebrugge (tours to Bruges), Belgium, Hamburg, Germany
2027 Sails: Feb 28, More...
33 Night - San Antonio to SouthamptonStarting in San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Manta, Ecuador, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL, Port Canaveral, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2027 Sails: Feb 28, More...
19 Night - San Antonio to Fort LauderdaleStarting in San Antonio CL (tours to Santiago), Chile, Coquimbo, Chile, Arica, Chile, Callao (tours to Lima), Peru, Manta, Ecuador, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Oranjestad, Aruba, Fort Lauderdale, FL
2027 Sails: Feb 28, More...
20 Night - Panama Canal NavigatorStarting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Port Antonio, Great Stirrup Cay, Miami
2027 Sails: Mar 5, More...
10 Night - Panama PotpourriStarting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City
2027 Sails: Mar 5, More...
18 Night - Valparaiso to MiamiStarting in Valparaiso, Arica, Lima (Callao), Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cozumel, Quintana Roo, Miami, Fl
2027 Sails: Mar 5, More...
19 Night - Southern America & Panama Canal Cruise : Lima, Panama City & CozumelStarting in San Antonio Cl, Coquimbo, Iquique, Arica, Pisco, Callao (Lima), Panama City (Fuerte Amador), Panama Canal (Cruising), Puerto Limon, Isla San Andres, Cozumel, Mexico, Miami, Florida
2027 Sails: Mar 10, More...
16 Night - Machu Picchu & Mayan RuinsStarting in Lima (Callao), Salaverry, Cruising the Pacific Ocean, Guayaquil, Manta, Cruising the Pacific Ocean, Golfito, Panama City, Panama Canal Transit, Puerto Limon, Cruising the Caribbean Sea, Roatan, Harvest Caye, Costa Maya, Mexico, Cruising the Straits of Florida, Miami
2027 Sails: Mar 10, More...
10 Night - Panama & Pristine IslesStarting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Port Antonio, Great Stirrup Cay, Miami
2027 Sails: Mar 15, More...
16 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Ensenada, Mexico, Los Angeles, California
2027 Sails: Mar 18, More...
