Panama City Cruises
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
11 Night - Pristine Islands of the Caribbean & the Panama Canal
Starting in Bridgetown, Barbados, Soufriere, St Lucia, Port Elizabeth VC, Bequia, Mayreau, Grenadines, Tobago Cays, Grenadines, Willemstad AN, Curacao, Cabo de La Vela, Colombia, Cartagena CO, San Blas Islands, Lemon Cay, Panama, Panama Canal Transit / Panama City, Panama City, Panama
2027 Sails: Oct 20, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 24, More...
41 Night - South America
Starting in Buenos Aires, Punta Del Este, Puerto Madryn, Port Stanley, Falkland Islands, Ushuaia, Punta Arenas, Cruising the Chilean Fjords, Laguna San Raphael, Puerto Chacabuco, Castro, Puerto Montt, Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 11, More...
21 Night - Star Collector : Windward Islands, Spanish Cities & Costa Rica
Starting in San Juan, St Georges, Grenada, Bequia, Mayreau, Les Saintes, Guadeloupe, Marigot Bay, San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas Islands, Panama, Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Nov 22, More...
17 Night - Panama Canal : Los Angeles to Miami
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama City, Panama, Panama Canal (Cruising), Panama, Cartagena CO, Miami, Florida
2027 Sails: Nov 27, More...12 Night - South America
Starting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Nov 29, More...23 Night - South America
Starting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 29, More...14 Night - Star Collector : Coffee, Canal & Callaloo : Central America, Columbia & the Caribbean
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas Islands, Panama, Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Nov 29, More...6 Night - South America
Starting in Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Dec 5, More...7 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
Click on a cruise ship itinerary that visits Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.
11 Night - Pristine Islands of the Caribbean & the Panama CanalStarting in Bridgetown, Barbados, Soufriere, St Lucia, Port Elizabeth VC, Bequia, Mayreau, Grenadines, Tobago Cays, Grenadines, Willemstad AN, Curacao, Cabo de La Vela, Colombia, Cartagena CO, San Blas Islands, Lemon Cay, Panama, Panama Canal Transit / Panama City, Panama City, Panama
2027 Sails: Oct 20, More...
16 Night - Panama Canal - Ocean to OceanStarting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 24, More...
41 Night - South AmericaStarting in Buenos Aires, Punta Del Este, Puerto Madryn, Port Stanley, Falkland Islands, Ushuaia, Punta Arenas, Cruising the Chilean Fjords, Laguna San Raphael, Puerto Chacabuco, Castro, Puerto Montt, Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 11, More...
21 Night - Star Collector : Windward Islands, Spanish Cities & Costa RicaStarting in San Juan, St Georges, Grenada, Bequia, Mayreau, Les Saintes, Guadeloupe, Marigot Bay, San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas Islands, Panama, Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Nov 22, More...
17 Night - Panama Canal : Los Angeles to MiamiStarting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama City, Panama, Panama Canal (Cruising), Panama, Cartagena CO, Miami, Florida
2027 Sails: Nov 27, More...
12 Night - South AmericaStarting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Nov 29, More...
23 Night - South AmericaStarting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 29, More...
14 Night - Star Collector : Coffee, Canal & Callaloo : Central America, Columbia & the CaribbeanStarting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas Islands, Panama, Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Nov 29, More...
6 Night - South AmericaStarting in Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Dec 5, More...
7 Night - Costa Rica & Panama CanalStarting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
