Panama City Cruises
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
19 Night - Panama Canal & the Americas
Starting in New York City, New York, Sail the Atlantic Ocean, San Salvador Island, Man of War Bay (Great Inagua), Port Antonio, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Panama City (Fuerte Amador), Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Santiago (Valparaiso)
2027 Sails: Oct 17, 2028: Oct 11, More...
20 Night - Repo - Panama Canal
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Great Stirrup Cay, Bahamas, Miami, Fl, New York City, Ny
2027 Sails: Oct 19, More...17 Night - Repo - Panama Canal
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Great Stirrup Cay, Bahamas, Miami, Fl
2027 Sails: Oct 19, More...
11 Night - Pristine Islands of the Caribbean & the Panama Canal
Starting in Bridgetown, Barbados, Soufriere, St Lucia, Port Elizabeth VC, Bequia, Mayreau, Grenadines, Tobago Cays, Grenadines, Willemstad AN, Curacao, Cabo de La Vela, Colombia, Cartagena CO, San Blas Islands, Lemon Cay, Panama, Panama Canal Transit / Panama City, Panama City, Panama
2027 Sails: Oct 20, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 24, More...
41 Night - South America
Starting in Buenos Aires, Punta Del Este, Puerto Madryn, Port Stanley, Falkland Islands, Ushuaia, Punta Arenas, Cruising the Chilean Fjords, Laguna San Raphael, Puerto Chacabuco, Castro, Puerto Montt, Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 11, More...
17 Night - Panama Canal : Los Angeles to Miami
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama City, Panama, Panama Canal (Cruising), Panama, Cartagena CO, Miami, Florida
2027 Sails: Nov 27, More...12 Night - South America
Starting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Nov 29, More...23 Night - South America
Starting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 29, More...11 Night - The Americas & Caribbean
Starting in Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Dec 11, More...
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
Click on a cruise ship itinerary that visits Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.
19 Night - Panama Canal & the AmericasStarting in New York City, New York, Sail the Atlantic Ocean, San Salvador Island, Man of War Bay (Great Inagua), Port Antonio, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Panama City (Fuerte Amador), Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Santiago (Valparaiso)
2027 Sails: Oct 17, 2028: Oct 11, More...
Deal link -> Special
20 Night - Repo - Panama CanalStarting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Great Stirrup Cay, Bahamas, Miami, Fl, New York City, Ny
2027 Sails: Oct 19, More...
Deal link -> Special
17 Night - Repo - Panama CanalStarting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Great Stirrup Cay, Bahamas, Miami, Fl
2027 Sails: Oct 19, More...
11 Night - Pristine Islands of the Caribbean & the Panama CanalStarting in Bridgetown, Barbados, Soufriere, St Lucia, Port Elizabeth VC, Bequia, Mayreau, Grenadines, Tobago Cays, Grenadines, Willemstad AN, Curacao, Cabo de La Vela, Colombia, Cartagena CO, San Blas Islands, Lemon Cay, Panama, Panama Canal Transit / Panama City, Panama City, Panama
2027 Sails: Oct 20, More...
16 Night - Panama Canal - Ocean to OceanStarting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 24, More...
41 Night - South AmericaStarting in Buenos Aires, Punta Del Este, Puerto Madryn, Port Stanley, Falkland Islands, Ushuaia, Punta Arenas, Cruising the Chilean Fjords, Laguna San Raphael, Puerto Chacabuco, Castro, Puerto Montt, Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 11, More...
17 Night - Panama Canal : Los Angeles to MiamiStarting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama City, Panama, Panama Canal (Cruising), Panama, Cartagena CO, Miami, Florida
2027 Sails: Nov 27, More...
12 Night - South AmericaStarting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Nov 29, More...
23 Night - South AmericaStarting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 29, More...
11 Night - The Americas & CaribbeanStarting in Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Dec 11, More...
