Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
22 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Chiapas, Mexico, Manzanillo, Mexico, Puerto Vallarta, Mexico, San Diego, California, San Francisco, California, Vancouver, BC, CA
2026 Sails: Apr 10, More...17 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Chiapas, Mexico, Manzanillo, Mexico, Puerto Vallarta, Mexico, San Diego, California
2026 Sails: Apr 10, More...
16 Night - Journeys - Panama Canal
Starting in Tampa, Fl, Grand Cayman, Cayman Islands, Cartagena CO, Panama Canal Transit, Puntarenas, Costa Rica, Cabo San Lucas, Mexico, Seattle, Wa
2026 Sails: Apr 11, More...
18 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca
2026 Sails: Apr 11, More...22 Night - Repo - Panama Canal
Starting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca, Astoria, Or, Victoria CA, Canada, Seattle, Wa
2026 Sails: Apr 11, More...
16 Night - Journeys - Panama Canal
Starting in Mobile, Al, Cartagena CO, Panama Canal Transit, Puntarenas, Costa Rica, Cabo San Lucas, Mexico, Seattle, Wa
2026 Sails: Apr 12, 2027: Mar 29, More...
17 Night - Panama Canal Westward Cruise
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cartagena CO, Colon, Panama, Panama Canal (Cruising), Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: Apr 13, More...
20 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California, Seattle, Washington
2026 Sails: Apr 13, More...
11 Night - Panama Canal & the Alluring Islands of the Caribbean
Starting in Panama City, Panama, Panama Canal Transit, Portobelo, Panama, Cayos Limones, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Klein Curacao, Curacao, Tobago Cays, St Vincent and the Grenadines, Bridgetown, Barbados
2026 Sails: Apr 13, More...
15 Night - Star Collector : Panama Canal, Costa Rica & Mexican Riviera Discovery
Starting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera, Curu, Costa Rica, Playas del Coco, Puerto Chiapas, Huatulco, Manzanillo, Puerto Vallarta
2026 Sails: Apr 13, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
22 Night - Panama CanalStarting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Chiapas, Mexico, Manzanillo, Mexico, Puerto Vallarta, Mexico, San Diego, California, San Francisco, California, Vancouver, BC, CA
2026 Sails: Apr 10, More...
17 Night - Panama CanalStarting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Chiapas, Mexico, Manzanillo, Mexico, Puerto Vallarta, Mexico, San Diego, California
2026 Sails: Apr 10, More...
16 Night - Journeys - Panama CanalStarting in Tampa, Fl, Grand Cayman, Cayman Islands, Cartagena CO, Panama Canal Transit, Puntarenas, Costa Rica, Cabo San Lucas, Mexico, Seattle, Wa
2026 Sails: Apr 11, More...
18 Night - Panama Canal - MiamiStarting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca
2026 Sails: Apr 11, More...
22 Night - Repo - Panama CanalStarting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca, Astoria, Or, Victoria CA, Canada, Seattle, Wa
2026 Sails: Apr 11, More...
16 Night - Journeys - Panama CanalStarting in Mobile, Al, Cartagena CO, Panama Canal Transit, Puntarenas, Costa Rica, Cabo San Lucas, Mexico, Seattle, Wa
2026 Sails: Apr 12, 2027: Mar 29, More...
17 Night - Panama Canal Westward CruiseStarting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cartagena CO, Colon, Panama, Panama Canal (Cruising), Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: Apr 13, More...
20 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California, Seattle, Washington
2026 Sails: Apr 13, More...
11 Night - Panama Canal & the Alluring Islands of the CaribbeanStarting in Panama City, Panama, Panama Canal Transit, Portobelo, Panama, Cayos Limones, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Klein Curacao, Curacao, Tobago Cays, St Vincent and the Grenadines, Bridgetown, Barbados
2026 Sails: Apr 13, More...
15 Night - Star Collector : Panama Canal, Costa Rica & Mexican Riviera DiscoveryStarting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera, Curu, Costa Rica, Playas del Coco, Puerto Chiapas, Huatulco, Manzanillo, Puerto Vallarta
2026 Sails: Apr 13, More...
