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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



HAL Zuiderdam Cruise Ship26 Night - Panama Canal & Eastern Caribbean
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Fort-De-France, Martinique, Roseau, Dominica, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 27, More...
HAL Zuiderdam Cruise Ship15 Night - Panama Canal
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 27, More...
NCL Norwegian Jade Cruise Ship12 Night - Panama Canal - Miami
Starting in Miami, Fl, Santa Marta, Colombia, Cartagena CO, Transit Panama Canal / At Sea, Panama City, Panama, Manta, Ecuador, Salaverry / Trujillo, Peru, Callao / Lima, Peru
2026 Sails: Feb 27, More...
Sea Cloud Spirit Cruises13 Night - Cruise from Puntarenas to Colon
Starting in Puntarenas, Playa Mantas / Punta Leona, Marina Flamingo / Playa Flamingo, Playa Panama, Quepos, Puerto Jimenez, Pearl Islands, Transit Panama Canal, San Blas Islands, Colon
2026 Sails: Mar 1, 2027: Mar 1, More...
Le Champlain Cruises10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), Colon, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Cebaco Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Mar 5, More...
HAL Volendam Cruise Ship71 Night - Grand World Voyage
Starting in Sydney AU, Townsville, Australia, Cairns, Australia, Scenic Cruising Torres Strait, Darwin, Australia, Slawi Bay, Komodo Island, Indonesia, Benoa (Denpasar), Bali, Indonesia, Crossing the Equator, Singapore, Phu My, Vietnam, Da Nang (Hue), Vietnam, Halong Bay, Vietnam, Hong Kong, China, Kaohsiung, Taiwan, Keelung (Taipei), Taiwan, Naha, Japan, Amami (Naze), Amami Oshima, Japan, Nagasaki, Japan, Shimizu, Japan, Yokohama (Tokyo), Japan, Hakodate, Japan, Cross International Dateline, Kodiak, Alaska, Sitka, Alaska, Ketchikan, Alaska, Seattle, Washington, San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: Mar 7, More...
HAL Oosterdam Cruise Ship31 Night - Panama Canal, Inca & South America Discovery
Starting in Buenos Aires, Argentina, Montevideo, Uruguay, Port Stanley, Falkland Islands, Scenic Cruising Cape Horn, Ushuaia, Argentina, Beagle Channel, Daylight cruising Glacier Alley, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Strait of Magellan, Puerto Montt, Chile, San Antonio CL (Santiago), Chile, Coquimbo (La Serena), Chile, General San Martin (Pisco), Peru, Callao (Lima), Peru, Salaverry (Trujillo), Peru, Manta, Ecuador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Mar 8, More...
Seabourn Quest Cruise Ship48 Night - Polynesia & Panama Canal Passage
Starting in Papeete, French Polynesia, Fakarava, Tuamotu, French Polynesia, Avatoru, Rangiroa, French Polynesia, Maroe Bay, Huahine Iti, French Polynesia, Raiatea, Society Islands, French Polynesia, Bora Bora, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Papeete, French Polynesia, Raiatea, Society Islands, French Polynesia, Bora Bora, French Polynesia, Crossing the Equator, Kahului, Maui, Honolulu, Hawaii, Kona, Hawaii, Long Beach, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Miami, Florida
2026 Sails: Mar 9, More...
Azamara Quest Cruise Ship11 Night - Panama Canal & Southern Caribbean Cruise : Cartagena, Aruba & Curacao
Starting in Panama City (Fuerte Amador), Panama Canal (Cruising), Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Kralendijk, Cabo Rojo, Miami, Florida
2026 Sails: Mar 15, More...
NCL Norwegian Jewel Cruise Ship11 Night - Panama Canal - Miami
Starting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Belize City, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Mar 15, More...


Panama Canal Cruises