Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
16 Night - Panama Canal
Starting in San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 8, More...
16 Night - Repo - Panama Canal
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Miami, Fl
2026 Sails: Oct 13, More...19 Night - Repo - Panama Canal
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Miami, Fl, New York City, Ny
2026 Sails: Oct 13, More...
10 Night - Pristine Islands of the Bahamas & the Panama Canal
Starting in Nassau, Bahamas, Staniel Cay, Bahamas, San Salvador Island, Bahamas, Cabo de La Vela, Colombia, Cartagena CO, San Blas, Panama, Bocas Del Toro, Panama, Panama Canal Transit / Panama City, Panama, Panama City, Panama
2026 Sails: Oct 16, More...
12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Oct 18, Dec 27, 2027: Jan 17, Feb 7, Feb 28, Mar 21, More...21 Night - Panama Canal & Southern Caribbean : Abc Islands
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Cabo Rojo, Dominican Republic, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 18, More...
10 Night - From Panama's Wild Beauty to Peruvian Shores
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Salaverry, Callao
2026 Sails: Oct 20, More...
14 Night - Panama Canal & Central America
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Roatan, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Oct 20, Nov 23, 2027: Jan 10, More...
19 Night - Panama Canal & the Americas
Starting in New York City, New York, Sail the Atlantic Ocean, San Salvador Island, Man of War Bay (Great Inagua), Port Antonio, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Panama City (Fuerte Amador), Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Santiago (Valparaiso)
2026 Sails: Oct 25, More...
10 Night - Caribbean & Panama
Starting in Galveston, Tx, Cozumel, Mexico, Limon, Costa Rica, Colon (Panama Canal), Panama, Isla Tropicale, Roatan, Galveston, Tx
2026 Sails: Oct 26, Dec 7, 2027: Jan 18, Mar 5, Apr 26, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
16 Night - Panama CanalStarting in San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 8, More...
16 Night - Repo - Panama CanalStarting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Miami, Fl
2026 Sails: Oct 13, More...
19 Night - Repo - Panama CanalStarting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Miami, Fl, New York City, Ny
2026 Sails: Oct 13, More...
10 Night - Pristine Islands of the Bahamas & the Panama CanalStarting in Nassau, Bahamas, Staniel Cay, Bahamas, San Salvador Island, Bahamas, Cabo de La Vela, Colombia, Cartagena CO, San Blas, Panama, Bocas Del Toro, Panama, Panama Canal Transit / Panama City, Panama, Panama City, Panama
2026 Sails: Oct 16, More...
12 Night - Panama Canal Discovery : Costa Rica & Greater AntillesStarting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Oct 18, Dec 27, 2027: Jan 17, Feb 7, Feb 28, Mar 21, More...
21 Night - Panama Canal & Southern Caribbean : Abc IslandsStarting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Cabo Rojo, Dominican Republic, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 18, More...
10 Night - From Panama's Wild Beauty to Peruvian ShoresStarting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Salaverry, Callao
2026 Sails: Oct 20, More...
14 Night - Panama Canal & Central AmericaStarting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Roatan, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Oct 20, Nov 23, 2027: Jan 10, More...
19 Night - Panama Canal & the AmericasStarting in New York City, New York, Sail the Atlantic Ocean, San Salvador Island, Man of War Bay (Great Inagua), Port Antonio, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Panama City (Fuerte Amador), Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Santiago (Valparaiso)
2026 Sails: Oct 25, More...
10 Night - Caribbean & PanamaStarting in Galveston, Tx, Cozumel, Mexico, Limon, Costa Rica, Colon (Panama Canal), Panama, Isla Tropicale, Roatan, Galveston, Tx
2026 Sails: Oct 26, Dec 7, 2027: Jan 18, Mar 5, Apr 26, More...
