Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
7 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Apr 13, More...
20 Night - Miami to Seattle
Starting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA
2026 Sails: Apr 14, More...30 Night - Miami to Seattle
Starting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA, Ketchikan, AK, Sitka, AK, Glacier Bay, AK, (Scenic Cruising), Juneau, AK, Skagway, AK, Tracy Arm Fjord, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Apr 14, More...
33 Night - Grand World Voyage
Starting in Yokohama (Tokyo), Japan, Hakodate, Japan, Cross International Dateline, Kodiak, Alaska, Sitka, Alaska, Ketchikan, Alaska, Seattle, Washington, San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: Apr 14, More...
10 Night - Vivid Western Caribbean
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Belize City, Roatan, Puerto Limon, Colon, Panama Canal Daylight Transit, Panama City
2026 Sails: Apr 14, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 16, More...
18 Night - Msc Grand Voyages
Starting in Miami, Cartagena CO, Colon, Panama, Panama Canal (Transit), Panama, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle
2026 Sails: Apr 23, More...10 Night - Canal & Coral Isles
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Puerto Limon, Roatan, Costa Maya, Mexico, Cozumel, Mexico, Miami
2026 Sails: Apr 24, More...
15 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 25, More...18 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca, Seattle, Wa
2026 Sails: Apr 25, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Costa Rica & Panama CanalStarting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Apr 13, More...
Deal link -> Special
20 Night - Miami to SeattleStarting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA
2026 Sails: Apr 14, More...
30 Night - Miami to SeattleStarting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA, Ketchikan, AK, Sitka, AK, Glacier Bay, AK, (Scenic Cruising), Juneau, AK, Skagway, AK, Tracy Arm Fjord, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Apr 14, More...
33 Night - Grand World VoyageStarting in Yokohama (Tokyo), Japan, Hakodate, Japan, Cross International Dateline, Kodiak, Alaska, Sitka, Alaska, Ketchikan, Alaska, Seattle, Washington, San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: Apr 14, More...
10 Night - Vivid Western CaribbeanStarting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Belize City, Roatan, Puerto Limon, Colon, Panama Canal Daylight Transit, Panama City
2026 Sails: Apr 14, More...
16 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 16, More...
18 Night - Msc Grand VoyagesStarting in Miami, Cartagena CO, Colon, Panama, Panama Canal (Transit), Panama, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle
2026 Sails: Apr 23, More...
10 Night - Canal & Coral IslesStarting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Puerto Limon, Roatan, Costa Maya, Mexico, Cozumel, Mexico, Miami
2026 Sails: Apr 24, More...
15 Night - Panama Canal - MiamiStarting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 25, More...
18 Night - Panama Canal - MiamiStarting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca, Seattle, Wa
2026 Sails: Apr 25, More...
