Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
10 Night - Passage to Panama
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City
2026 Sails: Jan 17, More...
8 Night - Panama Canal, Cartagena, San Blas Islands & More
Starting in Oranjestad, Cartagena CO, Bocas del Toro, San Blas, Panama, Panama Canal, Balboa / Fuerte Amador
2026 Sails: Jan 17, More...
21 Night - Panama Canal & Southern Caribbean : Abc Islands
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 18, More...12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, More...
15 Night - New York to Los Angeles
Starting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA
2026 Sails: Jan 19, More...44 Night - New York to Sydney
Starting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA, San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia
2026 Sails: Jan 19, More...18 Night - New York to San Francisco
Starting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA, San Francisco, CA
2026 Sails: Jan 19, More...109 Night - Full World Voyage
Starting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA, San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia, Brisbane, Australia, Yorkeys Knob (tours to Cairns), Australia, Darwin, NT, Australia, Bitung, Indonesia, Hong Kong, China, Chan May (tours to Hue or Da Nang), Vietnam, Singapore, Port Kelang (tours to Kuala Lumpur), Malaysia, Port Louis, Mauritius, Durban, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Dakar, Senegal, Tenerife, Spain, Cadiz (tours to Seville), Spain, Southampton, England, UK, Le Havre, France, New York, NY
2026 Sails: Jan 19, More...
10 Night - Secrets of Central America
Starting in Colon, Fuerte San Lorenzo, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Jan 19, More...
22 Night - Eastern Caribbean & Panama Canal
Starting in Miami, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 24, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Passage to PanamaStarting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City
2026 Sails: Jan 17, More...
8 Night - Panama Canal, Cartagena, San Blas Islands & MoreStarting in Oranjestad, Cartagena CO, Bocas del Toro, San Blas, Panama, Panama Canal, Balboa / Fuerte Amador
2026 Sails: Jan 17, More...
21 Night - Panama Canal & Southern Caribbean : Abc IslandsStarting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 18, More...
12 Night - Panama Canal Discovery : Costa Rica & Greater AntillesStarting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, More...
15 Night - New York to Los AngelesStarting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA
2026 Sails: Jan 19, More...
44 Night - New York to SydneyStarting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA, San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia
2026 Sails: Jan 19, More...
18 Night - New York to San FranciscoStarting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA, San Francisco, CA
2026 Sails: Jan 19, More...
109 Night - Full World VoyageStarting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA, San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia, Brisbane, Australia, Yorkeys Knob (tours to Cairns), Australia, Darwin, NT, Australia, Bitung, Indonesia, Hong Kong, China, Chan May (tours to Hue or Da Nang), Vietnam, Singapore, Port Kelang (tours to Kuala Lumpur), Malaysia, Port Louis, Mauritius, Durban, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Dakar, Senegal, Tenerife, Spain, Cadiz (tours to Seville), Spain, Southampton, England, UK, Le Havre, France, New York, NY
2026 Sails: Jan 19, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fuerte San Lorenzo, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Jan 19, More...
22 Night - Eastern Caribbean & Panama CanalStarting in Miami, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 24, More...
