Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
15 Night - Mexico, Panama & Peru Cruise : Progreso, Panama Canal & Lima
Starting in Miami, Florida, Progreso, Bocas del Toro, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Guayaquil, Salaverry (Trujillo), Callao (Lima)
2026 Sails: Jan 6, More...
116 Night - Full World Voyage
Starting in Hamburg, Germany, Rotterdam, Netherlands, Zeebrugge (tours to Bruges), Belgium, Southampton, England, UK, Funchal, Madeira, Portugal, Tenerife, Spain, Mindelo, St Vincent, Cape Verde, Walvis Bay, Namibia, Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia, Port Vila, Vanuatu, Suva, Fiji, Cross International Date Line (Cruise-by), Honolulu, HI, Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK, Hamburg, Germany
2026 Sails: Jan 6, More...
13 Night - Fort Lauderdale to Lima
Starting in Fort Lauderdale, Florida, Cozumel, Quintana Roo, Puerto Limon, Colon, Panama Canal Transit, Manta, Lima (Callao)
2026 Sails: Jan 6, More...101 Night - South America from Ft Lauderdale (Port Everglades) to Mahe Island
Starting in Fort Lauderdale, Cozumel, Quintana Roo, Puerto Limon, Colon, Panama Canal Transit, Manta, Lima, Easter Island, Nuku Hiva, Atuona / Hiva Oa, Fakarava, Bora Bora, Papeete, Aitutaki, Date Line lose a day, Nukualofa, Savusavu, Mystery Island, Noumea, Norfolk Island, Bay of Islands, Auckland, Hobart, Melbourne, Adelaide, Kangaroo Island, Port Lincoln, Esperance, Busselton, Fremantle, Geraldton, Broome, Darwin, Lembar / Lombok, Benoa, Singapore, Port Klang, Phuket, Trincomalee, Galle, Colombo, Cochin, Mahe
2026 Sails: Jan 6, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Jan 8, More...
21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 9, More...
7 Night - Central America Jewels & Panama Canal
Starting in Puntarenas, Golfito, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2026 Sails: Jan 9, More...
154 Night - The Sense of Adventure
Starting in Miami, Cruising the Florida Straits, Cruising the Caribbean Sea, Cartagena CO, Panama Canal Transit, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, Hilo, Kahului, Honolulu, Nawiliwili, Kailua-Kona, Hilo, Cruising the Pacific Ocean, Cruising the South Pacific, Rangiroa, Raiatea, Bora Bora, Papeete (Tahiti), Moorea, Huahine, Cruising the South Pacific, Pago Pago, Cross the International Date Line, Apia, Cruising the South Pacific, Suva, Lautoka, Cruising the South Pacific, Port Vila, Lifou Island, Mystery Island, Noumea, Cruising the South Pacific, Auckland, Bay of Islands, Cruising the Tasman Sea, Sydney AU, Cruising the Tasman Sea, Mooloolaba, Cruising the Coral Sea, Airlie Beach, Cairns, Cruising the Coral Sea, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Komodo, Bali (Benoa), Celukan Bawang (Bali), Surabaya, Semarang (Java), Cruising the Java Sea, Cruising the South China Sea, Ho Chi Minh City (Saigon), Cam Ranh, Cruising the South China Sea, Sihanoukville, Bangkok (Laem Chabang), Ko Samui, Cruising the Gulf of Thailand, Singapore, Kuala Lumpur (Port Klang), Langkawi, Phuket, Cruising the Andaman Sea, Cruising the Laccadive Sea, Galle, Colombo, Cochin (Kochi), Mangalore, Goa (Mormugao), Cruising the Laccadive Sea, Male, Cruising the Arabian Sea, Praslin (La Digue), Mahe, Cruising the Indian Ocean, Nosy Be, Mayotte, Cruising the Mozambique Channel, Maputo, Richards Bay, Durban, Cruising the Indian Ocean, Mossel Bay, Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Luanda, Cruising the Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Cotonou, Takoradi, Abidjan, Cruising the Atlantic Ocean, Dakar, Cruising the Atlantic Ocean, Mindelo (Porto Grande), Cruising the Atlantic Ocean, Santa Cruz de La Palma, Funchal (Madeira), Cruising the Atlantic Ocean, Cadiz, Lisbon, Cruising the Atlantic Ocean, Horta (Azores), Cruising the Atlantic Ocean, Hamilton, Cruising the Atlantic Ocean, Miami
2026 Sails: Jan 10, More...
14 Night - Journeys - Caribbean & Panama
Starting in Baltimore, MD, Celebration Key, the Bahamas, Ocho Rios, Jamaica, Limon, Costa Rica, Colon (Panama Canal), Panama, Grand Turk, Baltimore, MD
2026 Sails: Jan 11, More...98 Night - Southampton to Miami
Starting in Southampton, England, UK, Funchal, Madeira, Portugal, Tenerife, Spain, Mindelo, St Vincent, Cape Verde, Walvis Bay, Namibia, Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia, Port Vila, Vanuatu, Suva, Fiji, Cross International Date Line (Cruise-by), Honolulu, HI, Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Jan 11, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
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15 Night - Mexico, Panama & Peru Cruise : Progreso, Panama Canal & LimaStarting in Miami, Florida, Progreso, Bocas del Toro, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Guayaquil, Salaverry (Trujillo), Callao (Lima)
2026 Sails: Jan 6, More...
116 Night - Full World VoyageStarting in Hamburg, Germany, Rotterdam, Netherlands, Zeebrugge (tours to Bruges), Belgium, Southampton, England, UK, Funchal, Madeira, Portugal, Tenerife, Spain, Mindelo, St Vincent, Cape Verde, Walvis Bay, Namibia, Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia, Port Vila, Vanuatu, Suva, Fiji, Cross International Date Line (Cruise-by), Honolulu, HI, Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK, Hamburg, Germany
2026 Sails: Jan 6, More...
13 Night - Fort Lauderdale to LimaStarting in Fort Lauderdale, Florida, Cozumel, Quintana Roo, Puerto Limon, Colon, Panama Canal Transit, Manta, Lima (Callao)
2026 Sails: Jan 6, More...
101 Night - South America from Ft Lauderdale (Port Everglades) to Mahe IslandStarting in Fort Lauderdale, Cozumel, Quintana Roo, Puerto Limon, Colon, Panama Canal Transit, Manta, Lima, Easter Island, Nuku Hiva, Atuona / Hiva Oa, Fakarava, Bora Bora, Papeete, Aitutaki, Date Line lose a day, Nukualofa, Savusavu, Mystery Island, Noumea, Norfolk Island, Bay of Islands, Auckland, Hobart, Melbourne, Adelaide, Kangaroo Island, Port Lincoln, Esperance, Busselton, Fremantle, Geraldton, Broome, Darwin, Lembar / Lombok, Benoa, Singapore, Port Klang, Phuket, Trincomalee, Galle, Colombo, Cochin, Mahe
2026 Sails: Jan 6, More...
16 Night - Panama Canal - Ocean to OceanStarting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Jan 8, More...
21 Night - Southern Caribbean & Panama Canal : Abc IslandsStarting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 9, More...
7 Night - Central America Jewels & Panama CanalStarting in Puntarenas, Golfito, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2026 Sails: Jan 9, More...
154 Night - The Sense of AdventureStarting in Miami, Cruising the Florida Straits, Cruising the Caribbean Sea, Cartagena CO, Panama Canal Transit, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, Hilo, Kahului, Honolulu, Nawiliwili, Kailua-Kona, Hilo, Cruising the Pacific Ocean, Cruising the South Pacific, Rangiroa, Raiatea, Bora Bora, Papeete (Tahiti), Moorea, Huahine, Cruising the South Pacific, Pago Pago, Cross the International Date Line, Apia, Cruising the South Pacific, Suva, Lautoka, Cruising the South Pacific, Port Vila, Lifou Island, Mystery Island, Noumea, Cruising the South Pacific, Auckland, Bay of Islands, Cruising the Tasman Sea, Sydney AU, Cruising the Tasman Sea, Mooloolaba, Cruising the Coral Sea, Airlie Beach, Cairns, Cruising the Coral Sea, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Komodo, Bali (Benoa), Celukan Bawang (Bali), Surabaya, Semarang (Java), Cruising the Java Sea, Cruising the South China Sea, Ho Chi Minh City (Saigon), Cam Ranh, Cruising the South China Sea, Sihanoukville, Bangkok (Laem Chabang), Ko Samui, Cruising the Gulf of Thailand, Singapore, Kuala Lumpur (Port Klang), Langkawi, Phuket, Cruising the Andaman Sea, Cruising the Laccadive Sea, Galle, Colombo, Cochin (Kochi), Mangalore, Goa (Mormugao), Cruising the Laccadive Sea, Male, Cruising the Arabian Sea, Praslin (La Digue), Mahe, Cruising the Indian Ocean, Nosy Be, Mayotte, Cruising the Mozambique Channel, Maputo, Richards Bay, Durban, Cruising the Indian Ocean, Mossel Bay, Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Luanda, Cruising the Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Cotonou, Takoradi, Abidjan, Cruising the Atlantic Ocean, Dakar, Cruising the Atlantic Ocean, Mindelo (Porto Grande), Cruising the Atlantic Ocean, Santa Cruz de La Palma, Funchal (Madeira), Cruising the Atlantic Ocean, Cadiz, Lisbon, Cruising the Atlantic Ocean, Horta (Azores), Cruising the Atlantic Ocean, Hamilton, Cruising the Atlantic Ocean, Miami
2026 Sails: Jan 10, More...
14 Night - Journeys - Caribbean & PanamaStarting in Baltimore, MD, Celebration Key, the Bahamas, Ocho Rios, Jamaica, Limon, Costa Rica, Colon (Panama Canal), Panama, Grand Turk, Baltimore, MD
2026 Sails: Jan 11, More...
98 Night - Southampton to MiamiStarting in Southampton, England, UK, Funchal, Madeira, Portugal, Tenerife, Spain, Mindelo, St Vincent, Cape Verde, Walvis Bay, Namibia, Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia, Port Vila, Vanuatu, Suva, Fiji, Cross International Date Line (Cruise-by), Honolulu, HI, Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Jan 11, More...
