Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
7 Night - Costa Rica and the Panama Canal
Starting in San Jose, Costa Rica / Puerto Caldera / Embark Ship, Osa Conservation Area, Golfo Dulce / Osa Peninsula, Coiba National Park, Panama, Gulf of Panama Islets / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Colon / Panama City, Panama / Disembark Ship
2026 Sails: Jan 2, Feb 4, Feb 23, Mar 14, Nov 29, Dec 27, 2027: Jan 10, Feb 13, Feb 27, Mar 13, Dec 16, Dec 30, 2028: Jan 18, Feb 12, Mar 2, Mar 30, More...
11 Night - Panama Canal - Miami
Starting in Miami, Fl, Ocho Rios, Jamaica, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Jan 2, More...
7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2026 Sails: Jan 2, More...
22 Night - Tropical Escape Across the Canal
Starting in Miami, Cruising the Florida Straits, George Town, Ocho Rios, Jamaica, Cruising the Caribbean Sea, Bonaire (Kralendijk), Willemstad AN, Oranjestad, Cartagena CO, Cruising the Caribbean Sea, Puerto Limon, Panama Canal Transit, Panama City, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Vallarta, Cabo San Lucas, Cruising the Pacific Ocean, Ensenada, Los Angeles
2026 Sails: Jan 3, More...
14 Night - Panama to Jamaica
Starting in Balboa (Isla Flamenco), Panama, Panama Canal Transit, Portobelo, Panama, Bocas Del Toro, Panama, Puerto Limon, Costa Rica, Cove Bay / San Andres, Colombia, Providencia, Colombia, George Town, Grand Cayman, Cayman Brac, Cayman Islands, Montego Bay, Jamaica
2026 Sails: Jan 3, More...
14 Night - Journeys - Caribbean & Panama
Starting in Galveston, Tx, Montego Bay, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Galveston, Tx
2026 Sails: Jan 4, More...
11 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, Miami, Fl
2026 Sails: Jan 4, More...
22 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Honolulu, Hawaii
2026 Sails: Jan 5, More...
131 Night - Circle Pacific - Ft. Lauderdale to Los Angeles
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Kahului, Hawaii, Kona, Hawaii, Raiatea, French Polynesia, Moorea, French Polynesia, Tahiti (Papeete), French Polynesia, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Dravuni Island, Fiji, Port Vila, Vanuatu, Lifou, New Caledonia, Auckland, New Zealand, Tauranga, New Zealand, Picton, New Zealand, New Plymouth, New Zealand, Fiordland National Park (Scenic Cruising), Sydney AU, Burnie, Australia, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Bali (Benoa), Indonesia, Kuala Lumpur (Port Kelang), Malaysia, Penang, Malaysia, Singapore, Ko Samui, Thailand, Laem Chabang (for Bangkok), Thailand, Ho Chi Minh City (Phu My), Vietnam, Cam Ranh (Nha Trang), Vietnam, Halong Bay / Hanoi (Cai Lan), Vietnam, Scenic Cruising Halong Bay, Da Nang / Hue (Chan May), Vietnam, Hong Kong, Taipei (Keelung), Jeju (Seogwipo), South Korea, Yatsushiro, Japan, Kagoshima, Japan, Kochi, Japan, Osaka (for Kyoto), Japan, Shimizu (for Mount Fuji), Japan, Tokyo (Yokohama), Japan, Miyako, Japan, Aomori, Japan, Hakodate, Japan, Cross International Date Line, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Sitka, Alaska, Ketchikan, Alaska, Victoria CA, Vancouver, Canada, Seattle, Washington, Astoria, Oregon, Santa Barbara, California, Ensenada, Mexico, San Diego, California, Los Angeles, California
2026 Sails: Jan 5, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Jan 5, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Costa Rica and the Panama CanalStarting in San Jose, Costa Rica / Puerto Caldera / Embark Ship, Osa Conservation Area, Golfo Dulce / Osa Peninsula, Coiba National Park, Panama, Gulf of Panama Islets / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Colon / Panama City, Panama / Disembark Ship
2026 Sails: Jan 2, Feb 4, Feb 23, Mar 14, Nov 29, Dec 27, 2027: Jan 10, Feb 13, Feb 27, Mar 13, Dec 16, Dec 30, 2028: Jan 18, Feb 12, Mar 2, Mar 30, More...
11 Night - Panama Canal - MiamiStarting in Miami, Fl, Ocho Rios, Jamaica, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Jan 2, More...
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2026 Sails: Jan 2, More...
22 Night - Tropical Escape Across the CanalStarting in Miami, Cruising the Florida Straits, George Town, Ocho Rios, Jamaica, Cruising the Caribbean Sea, Bonaire (Kralendijk), Willemstad AN, Oranjestad, Cartagena CO, Cruising the Caribbean Sea, Puerto Limon, Panama Canal Transit, Panama City, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Vallarta, Cabo San Lucas, Cruising the Pacific Ocean, Ensenada, Los Angeles
2026 Sails: Jan 3, More...
14 Night - Panama to JamaicaStarting in Balboa (Isla Flamenco), Panama, Panama Canal Transit, Portobelo, Panama, Bocas Del Toro, Panama, Puerto Limon, Costa Rica, Cove Bay / San Andres, Colombia, Providencia, Colombia, George Town, Grand Cayman, Cayman Brac, Cayman Islands, Montego Bay, Jamaica
2026 Sails: Jan 3, More...
14 Night - Journeys - Caribbean & PanamaStarting in Galveston, Tx, Montego Bay, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Galveston, Tx
2026 Sails: Jan 4, More...
11 Night - Panama Canal - MiamiStarting in Miami, Fl, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, Miami, Fl
2026 Sails: Jan 4, More...
22 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Honolulu, Hawaii
2026 Sails: Jan 5, More...
131 Night - Circle Pacific - Ft. Lauderdale to Los AngelesStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Kahului, Hawaii, Kona, Hawaii, Raiatea, French Polynesia, Moorea, French Polynesia, Tahiti (Papeete), French Polynesia, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Dravuni Island, Fiji, Port Vila, Vanuatu, Lifou, New Caledonia, Auckland, New Zealand, Tauranga, New Zealand, Picton, New Zealand, New Plymouth, New Zealand, Fiordland National Park (Scenic Cruising), Sydney AU, Burnie, Australia, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Bali (Benoa), Indonesia, Kuala Lumpur (Port Kelang), Malaysia, Penang, Malaysia, Singapore, Ko Samui, Thailand, Laem Chabang (for Bangkok), Thailand, Ho Chi Minh City (Phu My), Vietnam, Cam Ranh (Nha Trang), Vietnam, Halong Bay / Hanoi (Cai Lan), Vietnam, Scenic Cruising Halong Bay, Da Nang / Hue (Chan May), Vietnam, Hong Kong, Taipei (Keelung), Jeju (Seogwipo), South Korea, Yatsushiro, Japan, Kagoshima, Japan, Kochi, Japan, Osaka (for Kyoto), Japan, Shimizu (for Mount Fuji), Japan, Tokyo (Yokohama), Japan, Miyako, Japan, Aomori, Japan, Hakodate, Japan, Cross International Date Line, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Sitka, Alaska, Ketchikan, Alaska, Victoria CA, Vancouver, Canada, Seattle, Washington, Astoria, Oregon, Santa Barbara, California, Ensenada, Mexico, San Diego, California, Los Angeles, California
2026 Sails: Jan 5, More...
16 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Jan 5, More...