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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Celebrity Ascent Cruises11 Night - Panama Canal & Perfect Day Holiday
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal (Cruising), Colon, Panama, Oranjestad, Aruba, Willemstad AN, Curacao, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2025 Sails: Dec 22, More...
Crystal Serenity Cruise Ship20 Night - The Americas & Caribbean
Starting in Fort Lauderdale, George Town (Grand Cayman), Cartagena CO, Panama Canal Transit, Puerto Caldera, Huatulco, Manzanillo, La Paz, Cabo San Lucas (Baja California Sur), Baja Magdalena, Isla Natividad (Sightseeing Only), Los Angeles
2025 Sails: Dec 22, More...
Crystal Serenity Cruise Ship8 Night - The Americas & Caribbean
Starting in Fort Lauderdale, George Town (Grand Cayman), Cartagena CO, Panama Canal Transit, Puerto Caldera
2025 Sails: Dec 22, More...
NCL Norwegian Pearl Cruise Ship11 Night - Panama Canal - Miami
Starting in Miami, Fl, Ocho Rios, Jamaica, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Miami, Fl
2025 Sails: Dec 22, More...
Caribbean Princess Cruise Ship12 Night - Caribbean with Costa Rica & Panama Canal
Starting in Fort Lauderdale, Florida, Aruba, Curacao, Cartagena CO, Panama Canal Partial Transit New Locks, Colon, Panama, Limon, Costa Rica, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2025 Sails: Dec 23, 2026: Jan 4, More...
Island Princess Cruise Ship16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2025 Sails: Dec 23, 2026: Feb 25, Dec 12, 2027: Feb 14, Apr 19, More...
Le Dumont-D'Urville Cruises7 Night - Central America Jewels & Panama Canal
Starting in Puntarenas, Golfito, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2025 Sails: Dec 26, More...
HAL Rotterdam Cruise Ship21 Night - Panama Canal & Southern Caribbean Holiday
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2025 Sails: Dec 28, More...
HAL Rotterdam Cruise Ship12 Night - Panama Canal Holiday : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2025 Sails: Dec 28, More...
Viking Mars Cruises14 Night - Panama Canal & Central America
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Roatan, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2025 Sails: Dec 30, 2027: Nov 5, Dec 9, Dec 23, 2028: Jan 26, Feb 9, More...


Panama Canal Cruises