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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Star Pride Cruises13 Night - Star Collector : Coffee, Canal & Callaloo : Central America, Colombia & the Caribbean
Starting in San Juan, Santo Domingo, Cartagena CO, San Blas, Panama, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2025 Sails: Dec 7, More...
Carnival Legend Cruise Ship10 Night - Caribbean & Panama
Starting in Galveston, Tx, Cozumel, Mexico, Limon, Costa Rica, Colon (Panama Canal), Panama, Mahogany Bay, Roatan, Galveston, Tx
2025 Sails: Dec 8, More...
Viking Mars Cruises10 Night - Classic Panama Canal Passage
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Cozumel, Mexico, Belize City, Roatan, Sail the Caribbean Sea, Puerto Limon, Colon, Scenic Sailing Panama Canal, Panama City (Fuerte Amador)
2025 Sails: Dec 10, More...
Star Pride Cruises7 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2025 Sails: Dec 13, 2026: Feb 9, Feb 23, More...
National Geographic Quest Cruises7 Night - The Panama Canal, Pearl Islands and Darien Jungle
Starting in Panama City, Panama / Balboa / Embark Ship, Punta Patino Nature Reserve, Playa Muerto, Darien National Park, Pearl Islands / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Portobelo, Colon / Disembark Ship / Panama City, Panama
2025 Sails: Dec 14, 2026: Jan 16, Dec 13, 2027: Jan 29, Nov 5, 2028: Jan 29, Mar 16, More...
HAL Rotterdam Cruise Ship21 Night - Southern Caribbean & Panama Canal Holiday
Starting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2025 Sails: Dec 19, More...
Le Dumont-D'Urville Cruises7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2025 Sails: Dec 19, More...
Oceania Vista Cruises77 Night - Spanning the Americas
Starting in Los Angeles, Cabo San Lucas, Puerto Vallarta, Manzanillo, Acapulco, Puerto Quetzal, Puntarenas, Panama Canal Daylight Transit, Cartagena CO, George Town, Miami, Gustavia, Roseau, Bridgetown, Devils Island, Belem (Icoaraci), Fortaleza, Salvador, Buzios, Brazil, Rio De Janeiro, Ilha Grande, Brazil, Sao Paulo (Santos), Porto Belo, Rio Grande, Punta Del Este, Montevideo, Buenos Aires, Montevideo, Port Stanley, Falkland Islands, Ushuaia, Punta Arenas, Puerto Montt, Santiago De Chile (Valparaiso), Coquimbo, Iquique, Pisco / Nazca Lines, Lima / Machu Picchu (Callao), Salaverry, Manta, Puntarenas, Acajutla, Acapulco, Cabo San Lucas, Ensenada, San Diego
2025 Sails: Dec 20, More...
Star Pride Cruises7 Night - Costa Rica & Panama Canal
Starting in Puerto Caldera, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon
2025 Sails: Dec 20, More...
National Geographic Quest Cruises7 Night - Costa Rica and the Panama Canal
Starting in Panama City, Panama / Colon / Embark Ship, Gatun Lake / Panama Canal Transit, Gulf of Panama Islets, Coiba National Park, Panama, Golfo Dulce / Osa Peninsula, Corcovado National Park, Puerto Caldera / Disembark Ship / San Jose
2025 Sails: Dec 21, 2026: Jan 23, Feb 11, Mar 2, Mar 21, Dec 20, 2027: Jan 3, Feb 6, Feb 20, Mar 6, Mar 20, Dec 4, Dec 23, 2028: Jan 6, Feb 5, Feb 19, Mar 23, Apr 6, More...


Panama Canal Cruises