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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Caribbean Princess Cruise Ship12 Night - Caribbean with Costa Rica & Panama Canal
Starting in Fort Lauderdale, Florida, Curacao, Cartagena CO, Panama Canal Partial Transit New Locks, Colon, Panama, Limon, Costa Rica, Celebration Key, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 30, 2027: Jan 10, More...
National Geographic Quest Cruises7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Panama City, Panama / Balboa / Embark Ship, Gatun Lake / Barro Colorado / Panama Canal Crossing, Portobelo, Guna Yala Archipelago, Capurgana and Sapzurro, Colombia, Santa Cruz de Lorica / San Antero / Tuchin, Cispata Bay / Sanguare Natural Reserve, Cartagena CO, Colombia / Disembark Ship
2026 Sails: Oct 31, More...
Royal Clipper Cruise Ship14 Night - Barbados to Panama
Starting in Bridgetown, Barbados, Soufriere Bay, St Lucia, Tobago Cays, Grenadines, St Georges, Grenada, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, Santa Marta, Colombia, Cartagena De Indias, Colombia, San Blas Archipelago, Panama, Panama Canal Transit, Balboa (Isla Flamenco), Panama
2026 Sails: Oct 31, More...
Viking Mars Cruises10 Night - Classic Panama Canal Passage
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Cozumel, Mexico, Belize City, Roatan, Sail the Caribbean Sea, Puerto Limon, Colon, Scenic Sailing Panama Canal, Panama City (Fuerte Amador)
2026 Sails: Nov 3, Dec 7, More...
Disney Magic Cruise Ship14 Night - Eastbound Panama Canal Cruise from San Diego Ending in Galveston
Starting in San Diego, Cabo San Lucas, Puerto Vallarta, Panama Canal, Cartagena ES, George Town, Grand Cayman, Galveston
2026 Sails: Nov 6, More...
NCL Norwegian Sun Cruise Ship12 Night - Panama Canal - Miami
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Cabo Rojo, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Netherlands Antilles, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, George Town, Cayman Islands, Miami, Fl
2026 Sails: Nov 6, More...
Sapphire Princess Cruise Ship16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Nov 6, More...
Viking Octantis Cruises17 Night - Panama & Scenic South America
Starting in Fort Lauderdale, Florida, Scenic Sailing Gulf of Mexico, Cozumel, Mexico, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Panama City (Fuerte Amador), Sail the Pacific Ocean, Manta, Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Santiago (Valparaiso)
2026 Sails: Nov 6, More...
Viking Octantis Cruises40 Night - The Americas & Antarctic Explorer
Starting in Fort Lauderdale, Florida, Scenic Sailing Gulf of Mexico, Cozumel, Mexico, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Panama City (Fuerte Amador), Sail the Pacific Ocean, Manta, Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Santiago (Valparaiso), Sail the Pacific Ocean, Scenic Sailing Chilean Fjords, Puerto Chacabuco, Scenic Sailing Chilean Fjords, Chilean Glaciers, Scenic Sailing Chilean Fjords, Punta Arenas, Chilean Glaciers, Garibaldi Fjord, Scenic Sailing Cape Horn, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing Cape Horn, Ushuaia
2026 Sails: Nov 6, More...
Le Bellot Cruises7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2026 Sails: Nov 7, More...


Panama Canal Cruises