Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
14 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, San Diego, California
2027 Sails: Apr 3, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2027 Sails: Apr 3, More...
11 Night - Pristine Islands of the Caribbean & the Panama Canal
Starting in Panama City, Panama, Panama City / Panama Canal Transit, San Blas Islands, Lemon Cay, Panama, Cartagena CO, Cabo de La Vela, Colombia, Willemstad AN, Curacao, Tobago Cays, Grenadines, Mayreau, Grenadines, Soufriere, St Lucia, Bridgetown, Barbados
2027 Sails: Apr 3, More...
16 Night - Journeys - Panama Canal
Starting in Tampa, Fl, Santa Marta, Colombia, Cartagena CO, Panama Canal Transit, Acapulco, Mexico, Cabo San Lucas, Mexico, Seattle, Wa
2027 Sails: Apr 4, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Apr 4, More...
17 Night - A Grand Journey Through Balmy Shores & Enchanting Nature to Panama's Wonders
Starting in San Juan, Gustavia, Little Bay, Basseterre, Key West, Miami, Ocho Rios, Jamaica, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Crossing the Panama Canal, Panama City (Amador)
2027 Sails: Apr 5, More...
11 Night - Panama Canal - Miami
Starting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2027 Sails: Apr 5, More...
30 Night - Msc World Cruise
Starting in Los Angeles, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Balboa, Panama, Cruising Panama Canal, La Romana, Dominican Republic, Road Town (Tortola), British Virgin Islands, Philipsburg, St Maarten, Las Palmas de Gran Canaria (Canary Islands), Spain, Ibiza (Balearic Islands), Spain, Naples (Pompeii), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France
2027 Sails: Apr 7, More...
18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Huatulco, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2027 Sails: Apr 8, More...25 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Huatulco, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington, Ketchikan, Alaska, Icy Strait Point, Alaska, Cruising Tracy Arm Fjord, Alaska, Juneau, Alaska, Victoria CA, Canada, Seattle, Washington
2027 Sails: Apr 8, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Panama CanalStarting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, San Diego, California
2027 Sails: Apr 3, More...
16 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2027 Sails: Apr 3, More...
11 Night - Pristine Islands of the Caribbean & the Panama CanalStarting in Panama City, Panama, Panama City / Panama Canal Transit, San Blas Islands, Lemon Cay, Panama, Cartagena CO, Cabo de La Vela, Colombia, Willemstad AN, Curacao, Tobago Cays, Grenadines, Mayreau, Grenadines, Soufriere, St Lucia, Bridgetown, Barbados
2027 Sails: Apr 3, More...
16 Night - Journeys - Panama CanalStarting in Tampa, Fl, Santa Marta, Colombia, Cartagena CO, Panama Canal Transit, Acapulco, Mexico, Cabo San Lucas, Mexico, Seattle, Wa
2027 Sails: Apr 4, More...
16 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Apr 4, More...
17 Night - A Grand Journey Through Balmy Shores & Enchanting Nature to Panama's WondersStarting in San Juan, Gustavia, Little Bay, Basseterre, Key West, Miami, Ocho Rios, Jamaica, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Crossing the Panama Canal, Panama City (Amador)
2027 Sails: Apr 5, More...
11 Night - Panama Canal - MiamiStarting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2027 Sails: Apr 5, More...
30 Night - Msc World CruiseStarting in Los Angeles, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Balboa, Panama, Cruising Panama Canal, La Romana, Dominican Republic, Road Town (Tortola), British Virgin Islands, Philipsburg, St Maarten, Las Palmas de Gran Canaria (Canary Islands), Spain, Ibiza (Balearic Islands), Spain, Naples (Pompeii), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France
2027 Sails: Apr 7, More...
18 Night - Msc Grand VoyagesStarting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Huatulco, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2027 Sails: Apr 8, More...
25 Night - Msc Grand VoyagesStarting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Huatulco, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington, Ketchikan, Alaska, Icy Strait Point, Alaska, Cruising Tracy Arm Fjord, Alaska, Juneau, Alaska, Victoria CA, Canada, Seattle, Washington
2027 Sails: Apr 8, More...
