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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Scenic Eclipse Cruises10 Night - Pristine Islands of the Bahamas & the Panama Canal
Starting in Nassau, Bahamas, Staniel Cay, Bahamas, San Salvador Island, Bahamas, Cabo de La Vela, Colombia, Cartagena CO, San Blas, Panama, Bocas del Toro, Panama, Panama Canal Transit / Panama City, Panama, Panama City, Panama
2026 Sails: Oct 16, More...
HAL Nieuw Amsterdam Cruise Ship12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Oct 18, Dec 27, 2027: Jan 17, Feb 7, Feb 28, Mar 21, More...
HAL Nieuw Amsterdam Cruise Ship21 Night - Panama Canal & Southern Caribbean : Abc Islands
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Cabo Rojo, Dominican Republic, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 18, More...
Star Legend Cruises70 Night - Star Collector : Grand Mediterranean and Latin America Adventure
Starting in Istanbul, Myrina (Lemnos), Mykonos, Kusadasi, Bodrum, Santorini, Delphi, Corinth Canal, Athens, Greece, Corinth Canal, Delphi, Corfu (Kerkyra), Argostoli, Messina (Taormina), Trapani, Cagliari, Barcelona, Mystery Port, Malaga, Tangier, Casablanca, Morocco, Funchal, Bridgetown, Anse Mitan, Pigeon Island, Castries, The Pitons, Mayreau, St Georges, Bequia, Bridgetown, Rodney Bay, The Pitons, Scarborough, Tobago, Bequia, Mayreau, Kralendijk, Willemstad AN, Oranjestad, Cartagena CO, Bocas del Toro, San Blas, Panama, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Punta Leona, Costa Rica, Curu, Costa Rica, Playa Flamingo, Puerto Caldera
2026 Sails: Oct 19, More...
L'Austral Cruises10 Night - From Panama's Wild Beauty to Peruvian Shores
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Salaverry, Callao
2026 Sails: Oct 20, More...
Viking Mars Cruises14 Night - Panama Canal & Central America
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Roatan, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Oct 20, Nov 23, 2027: Jan 10, More...
Viking Polaris Cruises19 Night - Panama Canal & the Americas
Starting in New York City, New York, Sail the Atlantic Ocean, San Salvador Island, Man of War Bay (Great Inagua), Port Antonio, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Panama City (Fuerte Amador), Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Santiago (Valparaiso)
2026 Sails: Oct 25, More...
Carnival Miracle Cruise Ship10 Night - Caribbean & Panama
Starting in Galveston, Tx, Cozumel, Mexico, Limon, Costa Rica, Colon (Panama Canal), Panama, Isla Tropicale, Roatan, Galveston, Tx
2026 Sails: Oct 26, Dec 7, 2027: Jan 18, Mar 5, Apr 26, More...
Brilliant Lady Cruises17 Night - Picturesque Panama Canal Collective
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama City, Panama, Panama Canal (Cruising), Panama, Cartagena CO, Miami, Florida
2026 Sails: Oct 29, More...
HAL Nieuw Amsterdam Cruise Ship21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Cabo Rojo, Dominican Republic, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2026 Sails: Oct 30, More...


Panama Canal Cruises