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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



HAL Nieuw Amsterdam Cruise Ship21 Night - Panama Canal & Southern Caribbean Discovery
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Nov 8, More...
HAL Nieuw Amsterdam Cruise Ship12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2026 Sails: Nov 8, More...
Caribbean Princess Cruise Ship12 Night - Caribbean with Costa Rica & Panama Canal
Starting in Fort Lauderdale, Florida, Aruba, Cartagena CO, Panama Canal Partial Transit New Locks, Colon, Panama, Limon, Costa Rica, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Nov 11, Dec 17, Dec 29, 2027: Feb 3, Feb 15, More...
Evrima Cruises7 Night - San Juan / Panama City
Starting in San Juan, Casa de Campo, Cartagena CO, Guna Yala, San Blas Islands, Transit Panama Canal, Panama City
2026 Sails: Nov 12, More...
Viking Mars Cruises10 Night - Classic Panama Canal Passage
Starting in Panama City (Fuerte Amador), Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Roatan, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Nov 13, More...
Le Bellot Cruises7 Night - Central America Jewels & Panama Canal
Starting in Puntarenas, Golfito, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2026 Sails: Nov 14, More...
Royal Clipper Cruise Ship14 Night - Panama to Antigua
Starting in Balboa (Isla Flamenco), Panama, Panama Canal Transit, San Blas Archipelago, Panama, Cartagena De Indias, Colombia, Santa Marta, Colombia, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, St Georges, Grenada, Soufriere Bay, St Lucia, Deshaies, Guadeloupe, St Johns AG
2026 Sails: Nov 14, More...
HAL Oosterdam Cruise Ship31 Night - Panama Canal, Inca & South America : Chilean Fjords
Starting in Fort Lauderdale, Florida, Georgetown, Cayman Islands, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Daylight cruising Glacier Alley, Ushuaia, Argentina, Scenic Cruising Cape Horn, Port Stanley, Falkland Islands, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Nov 18, More...
HAL Oosterdam Cruise Ship16 Night - Inca & Panama Canal Discovery : Lima Overnight
Starting in Fort Lauderdale, Florida, Georgetown, Cayman Islands, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile
2026 Sails: Nov 18, 2027: Nov 16, More...
NCL Norwegian Sun Cruise Ship11 Night - Panama Canal - Miami
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Falmouth, Jamaica, George Town, Cayman Islands, Miami, Fl
2026 Sails: Nov 18, Nov 29, More...


Panama Canal Cruises