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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



Costa Cruise Lines, Costa Diadema
Costa Diadema25 Night - Transatlantic from Rio De Janeiro
Starting in Rio De Janeiro, Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon, Leixoes, Vigo, Le Havre, Southampton, Zeebrugge, Kiel
2026 Sails: Apr 20, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema16 Night - Transatlantic from Rio De Janeiro
Starting in Rio De Janeiro, Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon
2026 Sails: Apr 20, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema13 Night - Transatlantic from Salvador Bahia
Starting in Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon
2026 Sails: Apr 23, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema22 Night - Transatlantic from Salvador Bahia
Starting in Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon, Leixoes, Vigo, Le Havre, Southampton, Zeebrugge, Kiel
2026 Sails: Apr 23, More...
Lindblad Expeditions Tours, Delfin III Tours
Delfin III Tours9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Apr 23, May 21, Jun 4, Jul 23, Aug 13, Aug 20, Sep 10, Nov 5, Nov 26, Dec 3, More...
MSC Cruises, MSC Poesia
MSC Poesia18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2026 Sails: Apr 23, More...
MSC Cruises, MSC Poesia
MSC Poesia14 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Apr 23, More...
Oceania Cruises, Oceania Insignia
Oceania Insignia10 Night - Canal & Coral Isles
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Puerto Limon, Roatan, Costa Maya, Mexico, Cozumel, Mexico, Miami
2026 Sails: Apr 24, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy15 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 25, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy18 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca, Seattle, Wa
2026 Sails: Apr 25, More...

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South America Cruises