South America River Cruises
River Cruises that visit South America
River Cruises by region
See all South America Cruises
River cruises by river name
Related areas: Brazil : Colombia : Ecuador : Peru
9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2025 Sails: Dec 15, 2026: Apr 6, May 4, May 18, Jun 1, Jun 15, Aug 10, Aug 24, Sep 7, Oct 5, Nov 2, Nov 16, Nov 30, Dec 14, More...7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2025 Sails: Nov 19, Dec 17, Dec 31, 2026: Apr 8, May 6, May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Oct 7, Nov 4, Nov 18, Dec 2, Dec 16, More...7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2025 Sails: Nov 26, Dec 10, 2026: Mar 18, Apr 1, Apr 15, Apr 29, May 13, May 27, Jun 10, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Sep 30, Oct 28, Nov 11, Nov 25, More...
7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2025 Sails: Nov 29, Dec 13, 2026: Jan 24, Feb 7, Apr 4, Apr 18, May 2, May 30, Jul 11, Aug 22, Sep 5, Oct 17, Nov 14, Nov 28, Dec 12, More...
9 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2025 Sails: Dec 6, Dec 13, Dec 20, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2025 Sails: Dec 12, 2026: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 2, Oct 30, Nov 13, Nov 27, Dec 11, More...
9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jan 1, Jan 5, Feb 5, Feb 9, Feb 12, Feb 23, Mar 5, Mar 9, Apr 23, Apr 27, May 21, Jun 4, Jun 8, Jul 23, Jul 27, Aug 13, Aug 20, Aug 24, Sep 10, Sep 14, Nov 5, Nov 26, Dec 3, More...7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Jan 3, Feb 28, Apr 11, Apr 25, May 9, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...5 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jan 5, Feb 9, Feb 16, Feb 23, Mar 9, Apr 27, May 25, Jun 8, Jul 27, Aug 17, Aug 24, Sep 14, Nov 9, Nov 30, Dec 7, More...8 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jan 10, Jan 17, Jan 24, Feb 28, Mar 14, Mar 21, Mar 28, Apr 11, Apr 18, Apr 25, May 16, Jun 20, Jun 27, Jul 18, Jul 25, Aug 1, Aug 8, Sep 5, Sep 19, Sep 26, Oct 3, Oct 17, Nov 14, Dec 5, More...
River Cruises that visit South America
River Cruises by region
See all South America Cruises
Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Brazil : Colombia : Ecuador : Peru
9 Night - Wonders of Colombia with in Cartagena Pre CruiseStarting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2025 Sails: Dec 15, 2026: Apr 6, May 4, May 18, Jun 1, Jun 15, Aug 10, Aug 24, Sep 7, Oct 5, Nov 2, Nov 16, Nov 30, Dec 14, More...
7 Night - Wonders of ColombiaStarting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2025 Sails: Nov 19, Dec 17, Dec 31, 2026: Apr 8, May 6, May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Oct 7, Nov 4, Nov 18, Dec 2, Dec 16, More...
7 Night - Magic of ColombiaStarting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2025 Sails: Nov 26, Dec 10, 2026: Mar 18, Apr 1, Apr 15, Apr 29, May 13, May 27, Jun 10, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Sep 30, Oct 28, Nov 11, Nov 25, More...
7 Night - Magic of ColombiaStarting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2025 Sails: Nov 29, Dec 13, 2026: Jan 24, Feb 7, Apr 4, Apr 18, May 2, May 30, Jul 11, Aug 22, Sep 5, Oct 17, Nov 14, Nov 28, Dec 12, More...
9 Night - Upper Amazon : a River ExpeditionStarting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2025 Sails: Dec 6, Dec 13, Dec 20, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2025 Sails: Dec 12, 2026: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 2, Oct 30, Nov 13, Nov 27, Dec 11, More...
9 Night - Exploring Peru : Machu Picchu and the AmazonStarting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jan 1, Jan 5, Feb 5, Feb 9, Feb 12, Feb 23, Mar 5, Mar 9, Apr 23, Apr 27, May 21, Jun 4, Jun 8, Jul 23, Jul 27, Aug 13, Aug 20, Aug 24, Sep 10, Sep 14, Nov 5, Nov 26, Dec 3, More...
7 Night - Wonders of ColombiaStarting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Jan 3, Feb 28, Apr 11, Apr 25, May 9, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
5 Night - Upper Amazon : a River ExpeditionStarting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jan 5, Feb 9, Feb 16, Feb 23, Mar 9, Apr 27, May 25, Jun 8, Jul 27, Aug 17, Aug 24, Sep 14, Nov 9, Nov 30, Dec 7, More...
8 Night - Upper Amazon : a River ExpeditionStarting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jan 10, Jan 17, Jan 24, Feb 28, Mar 14, Mar 21, Mar 28, Apr 11, Apr 18, Apr 25, May 16, Jun 20, Jun 27, Jul 18, Jul 25, Aug 1, Aug 8, Sep 5, Sep 19, Sep 26, Oct 3, Oct 17, Nov 14, Dec 5, More...
