South America River Cruises
River Cruises that visit South America
River Cruises by region
See all South America Cruises
River cruises by river name
Related areas: Brazil : Colombia : Ecuador : Peru
9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: May 18, Jun 1, Jun 15, Aug 10, Aug 24, Sep 7, Nov 2, Nov 16, Nov 30, Dec 14, More...7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, Dec 30, More...10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: May 21, Jun 4, Jul 23, Aug 13, Aug 20, Sep 10, Nov 5, Nov 26, Dec 3, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...5 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: May 25, Jun 8, Jul 27, Aug 17, Aug 24, Sep 14, Nov 9, Nov 30, Dec 7, More...7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: May 27, Jun 10, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Oct 28, Nov 11, Nov 25, Dec 9, More...
10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...
River Cruises that visit South America
River Cruises by region
See all South America Cruises
Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Brazil : Colombia : Ecuador : Peru
9 Night - Wonders of Colombia with in Cartagena Pre CruiseStarting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: May 18, Jun 1, Jun 15, Aug 10, Aug 24, Sep 7, Nov 2, Nov 16, Nov 30, Dec 14, More...
7 Night - Wonders of ColombiaStarting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, Dec 30, More...
10 Night - Wonders of Colombia with in Panama City Post CruiseStarting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
9 Night - Exploring Peru : Machu Picchu and the AmazonStarting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: May 21, Jun 4, Jul 23, Aug 13, Aug 20, Sep 10, Nov 5, Nov 26, Dec 3, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...
5 Night - Upper Amazon : a River ExpeditionStarting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: May 25, Jun 8, Jul 27, Aug 17, Aug 24, Sep 14, Nov 9, Nov 30, Dec 7, More...
7 Night - Magic of ColombiaStarting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: May 27, Jun 10, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Oct 28, Nov 11, Nov 25, Dec 9, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...
