South America Cruises
Cruises that visit South America
Cruises by region
See all South America River Cruises
Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay
11 Night - Antarctica by Helicopter : Icebergs, Mountains and Remote Lands
Starting in Arrive in Buenos Aires, Argentina, Fly to Ushuaia and Embark, Crossing the Drake, Weddell Sea by Water, Land, and Air, Disembark in Ushuaia and Fly to Buenos Aires
2025 Sails: Nov 27, 2026: Nov 27, Dec 7, More...
3 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Itajai, Brazil, Santos, Brazil
2025 Sails: Nov 28, Dec 5, Dec 8, Dec 11, Dec 18, 2026: Apr 2, Apr 9, Apr 16, More...
2 Night - South America from Santos to Itajai
Starting in Santos, Brazil, Itajai, Brazil
2025 Sails: Nov 28, More...
24 Night - The Americas & Caribbean
Starting in Fort Lauderdale, George Town (Grand Cayman), Montego Bay, Santo Domingo, San Juan, Marigot, St Martin, Fort-de-France, Bridgetown, St Georges, Kralendijk, Willemstad AN, Oranjestad, Aruba, Cartagena CO, Santo Domingo, Samana, Grand Turk, Freeport, Fort Lauderdale
2025 Sails: Nov 28, More...
21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2025 Sails: Nov 28, More...
15 Night - Galapagos by Catamaran, Machu Picchu and Peru's Land of the Inca
Starting in Quito or Guayaquil, Ecuador, Quito or Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2025 Sails: Nov 28, Dec 5, Dec 12, Dec 19, 2026: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 20, Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 26, More...
9 Night - Galapagos by Catamaran : An Intimate Voyage
Starting in Quito or Guayaquil, Ecuador, Quito or Guayaquil, Galapagos Islands, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2025 Sails: Nov 28, Dec 5, Dec 12, Dec 19, 2026: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 20, Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 26, More...
6 Night - Southeastern Galapagos Islands Roundtrip from Baltra Island
Starting in Santa Cruz Island, Las Bachas, Santa Cruz Island, Punta Pitt (San Cristobal), Cerro Colorado (San Cristobal Island), Gardner Bay (Espanola Island), Punta Suarez (Espanola Island), Cormorant Point (Floreana Island), Post Office Bay / Baroness Cove (Floreana Island), Punta Moreno (Isabela Island), Punta Mangle (Fernandina Island), Eden Islet, North Seymour Island, Baltra Island
2025 Sails: Nov 28, Dec 12, Dec 26, More...
6 Night - Southeastern Galapagos Islands Roundtrip from Baltra Island
Starting in Baltra Island / Santa Cruz Island, San Cristobal Island, Espanola Island, Floreana Island, Isabela Island / Fernandina Island, Eden Islet / North Seymour Island, Baltra
2025 Sails: Nov 28, Dec 12, More...
18 Night - Lisbon to Rio De Janeiro
Starting in Lisbon, Funchal, Madeira, Santa Cruz de La Palma, Mindelo, Recife, Salvador De Bahia, Rio De Janeiro
2025 Sails: Nov 28, More...
Cruises that visit South America
Cruises by region
See all South America River Cruises
Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay
11 Night - Antarctica by Helicopter : Icebergs, Mountains and Remote LandsStarting in Arrive in Buenos Aires, Argentina, Fly to Ushuaia and Embark, Crossing the Drake, Weddell Sea by Water, Land, and Air, Disembark in Ushuaia and Fly to Buenos Aires
2025 Sails: Nov 27, 2026: Nov 27, Dec 7, More...
3 Night - South America Roundtrip from SantosStarting in Santos, Brazil, Itajai, Brazil, Santos, Brazil
2025 Sails: Nov 28, Dec 5, Dec 8, Dec 11, Dec 18, 2026: Apr 2, Apr 9, Apr 16, More...
2 Night - South America from Santos to ItajaiStarting in Santos, Brazil, Itajai, Brazil
2025 Sails: Nov 28, More...
24 Night - The Americas & CaribbeanStarting in Fort Lauderdale, George Town (Grand Cayman), Montego Bay, Santo Domingo, San Juan, Marigot, St Martin, Fort-de-France, Bridgetown, St Georges, Kralendijk, Willemstad AN, Oranjestad, Aruba, Cartagena CO, Santo Domingo, Samana, Grand Turk, Freeport, Fort Lauderdale
2025 Sails: Nov 28, More...
21 Night - Southern Caribbean & Panama Canal : Abc IslandsStarting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2025 Sails: Nov 28, More...
15 Night - Galapagos by Catamaran, Machu Picchu and Peru's Land of the IncaStarting in Quito or Guayaquil, Ecuador, Quito or Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2025 Sails: Nov 28, Dec 5, Dec 12, Dec 19, 2026: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 20, Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 26, More...
9 Night - Galapagos by Catamaran : An Intimate VoyageStarting in Quito or Guayaquil, Ecuador, Quito or Guayaquil, Galapagos Islands, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2025 Sails: Nov 28, Dec 5, Dec 12, Dec 19, 2026: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 20, Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 26, More...
6 Night - Southeastern Galapagos Islands Roundtrip from Baltra IslandStarting in Santa Cruz Island, Las Bachas, Santa Cruz Island, Punta Pitt (San Cristobal), Cerro Colorado (San Cristobal Island), Gardner Bay (Espanola Island), Punta Suarez (Espanola Island), Cormorant Point (Floreana Island), Post Office Bay / Baroness Cove (Floreana Island), Punta Moreno (Isabela Island), Punta Mangle (Fernandina Island), Eden Islet, North Seymour Island, Baltra Island
2025 Sails: Nov 28, Dec 12, Dec 26, More...
6 Night - Southeastern Galapagos Islands Roundtrip from Baltra IslandStarting in Baltra Island / Santa Cruz Island, San Cristobal Island, Espanola Island, Floreana Island, Isabela Island / Fernandina Island, Eden Islet / North Seymour Island, Baltra
2025 Sails: Nov 28, Dec 12, More...
18 Night - Lisbon to Rio De JaneiroStarting in Lisbon, Funchal, Madeira, Santa Cruz de La Palma, Mindelo, Recife, Salvador De Bahia, Rio De Janeiro
2025 Sails: Nov 28, More...