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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Uruguay



Ultramarine Tours13 Night - Antarctica by Helicopter : Crossing the Circle and the Peninsula
Starting in Arrive in Buenos Aires, Argentina, Fly to Ushuaia and Embark, Crossing the Drake, South Shetland Islands and Antarctic Peninsula, Antarctic Circle, Northbound Along the Peninsula, Crossing the Drake Passage, Disembark in Ushuaia and Fly to Buenos Aires
2027 Sails: Feb 16, More...
Star Legend14 Night - Star Collector : Windward Islands & Spanish New World
Starting in Fuerte Amador, Panama City, Panama Canal Transit, Bocas del Toro, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, St Georges, Grenada, Rodney Bay, Sunset Cruising Pitons, Mayreau, Bequia, Bridgetown, Barbados
2027 Sails: Feb 16, More...
Star Legend6 Night - Panama Canal, Cartagena, San Blas Islands & More
Starting in Fuerte Amador, Panama City, Panama Canal Transit, Bocas del Toro, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba
2027 Sails: Feb 16, More...
AmaMagdalena Tours13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Feb 17, Mar 31, Apr 28, May 12, May 26, Jun 23, Sep 1, Sep 15, Sep 29, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, 2028: Jan 5, Mar 1, Mar 15, Apr 12, Apr 26, May 24, Jun 7, Aug 16, Aug 30, Sep 13, More...
AmaMagdalena Tours10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Feb 17, Mar 17, Mar 31, Apr 28, May 12, May 26, Jun 23, Sep 1, Sep 15, Sep 29, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, 2028: Jan 5, Mar 1, Mar 15, Apr 12, Apr 26, May 24, Jun 7, Aug 16, Aug 30, More...
Azamara Journey21 Night - Antarctica & Chilean Fjords Cruise : Buenos Aires, Ushuaia & Santiago
Starting in Buenos Aires, Montevideo, Punta Del Este, Port Stanley, Falkland Islands, Sailing Nelson Strait, Sailing Half Moon Island, Sailing Melchior Islands, Sailing Paradise Bay, Sailing the Antarctic Peninsula, Ushuaia, Sailing in the Beagle Channel, Ushuaia, Punta Arenas, Sailing in the Chilean Fjords, Puerto Chacabuco, Puerto Montt, San Antonio Cl
2027 Sails: Feb 17, More...
Azamara Journey40 Night - Buenos Aires to Miami Grand Voyage
Starting in Buenos Aires, Montevideo, Punta Del Este, Port Stanley, Falkland Islands, Sailing Nelson Strait, Sailing Half Moon Island, Sailing Melchior Islands, Sailing Paradise Bay, Sailing the Antarctic Peninsula, Ushuaia, Sailing in the Beagle Channel, Ushuaia, Punta Arenas, Sailing in the Chilean Fjords, Puerto Chacabuco, Puerto Montt, San Antonio Cl, Coquimbo, Iquique, Arica, Pisco, Callao (Lima), Panama City (Fuerte Amador), Panama Canal (Cruising), Puerto Limon, Isla San Andres, Cozumel, Mexico, Miami, Florida
2027 Sails: Feb 17, More...
EXPLORA I12 Night - A Journey from Amazon Adventures to Caribbean Charms
Starting in Manaus, Parintins, Alter Do Chao, Macapa, Devils Island, Bequia, Bridgetown, Castries, Gustavia, Basseterre, San Juan
2027 Sails: Feb 17, More...
EXPLORA I19 Night - An Extended Journey of Rainforest Wonders & Ocean Serenity
Starting in Manaus, Parintins, Alter Do Chao, Macapa, Devils Island, Bequia, Bridgetown, Castries, Gustavia, Basseterre, San Juan, St Johns AG, Antigua, Road Bay, Spanish Town (Virgin Gorda), Grand Turk, Miami
2027 Sails: Feb 17, More...
National Geographic Resolution Tours17 Night - Antarctica and Patagonia : Legendary Ice and Epic Fjords
Starting in Santiago, Chile or Buenos Aires, Argentina, Ushuaia, Argentina / Embark Ship, At Sea / Drake Passage, Antarctica, Chilean Fjords, Tierra del Fuego : Karukinka Natural Park and Ainsworth Bay, Francisco Coloane Marine Park, Kirke Narrows / Puerto Natales, Puerto Natales and Torres del Paine National Park, Puerto Natales / Disembark Ship / Santiago
2027 Sails: Feb 17, More...


South America Cruises