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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Uruguay



Scenic Eclipse28 Night - Ultimate Antarctica & the Fjords of Southern Chile
Starting in Buenos Aires, Argentina, Buenos Aires / Ushuaia, Antarctica, At Sea / Ushuaia, Ushuaia, Cape Horn and Murray Channel, Chilean Fjords, Cruising Beagle Channel and Cockburn Channel, Aguila and Condor Glacier, Cruise Magdalena and Gabriel Channel (narrow) Tucker Islets, Admiralty Sound and Ainsworth Bay, Cruise Whiteside Canal and Strait of Magellan, Punta Arenas, Chile, Cruise Strait of Magellan and Atlantic Ocean, Isla Pinguino, Punta Piramides, Argentina, Montevideo, Uruguay, Buenos Aires
2027 Sails: Feb 17, More...
Costa Serena9 Night - South America Roundtrip from Buenos Aires
Starting in Buenos Aires, Argentina, Montevideo, Uruguay, Camboriu, Brazil, Camboriu Bay, Abraao (Ilha Grande), Rio de Janeiro, Brazil, Baia De Copacabana, Ilhabela, Brazil, Buenos Aires, Argentina
2027 Sails: Feb 18, More...
MS Roald Amundsen Tours15 Night - Antarctic Circle Expedition
Starting in Buenos Aires, Buenos Aires / Ezeiza Airport (International), Ushuaia Airport, Ushuaia, South Shetland, Gerlache Strait, Petermann Island, Crystal Sound, Marguerite Bay, Penola Strait, Ushuaia, Ushuaia Airport
2027 Sails: Feb 18, More...
Nieuw Amsterdam21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2027 Sails: Feb 19, More...
MS Fram Tours22 Night - In-Depth Antarctica, Falklands & South Georgia Expedition
Starting in Santiago De Chile Airport, Santiago, Santiago De Chile Airport, Punta Arenas Airport, Punta Arenas, West Point Island, New Island, Saunders Island, Carcass Island, Port Stanley, Cape Rosa, Prion Island, Godthul, Grytviken, Fortuna Bay, Stromness, St Andrews Bay, Antarctic Sound, South Shetland, Gerlache Strait, South Shetland, Puerto Williams, Punta Arenas, Punta Arenas Airport
2027 Sails: Feb 19, More...
AmaMagdalena7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO
2027 Sails: Feb 20, Mar 6, Mar 20, Apr 3, May 1, May 15, May 29, Jun 26, Sep 4, Sep 18, Oct 2, Oct 30, Nov 13, Nov 27, Dec 11, Dec 25, 2028: Jan 8, Mar 4, Mar 18, Apr 15, Apr 29, May 27, Jun 10, Aug 19, More...
AmaMagdalena Tours10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Feb 20, Apr 3, May 1, May 15, May 29, Jun 26, Sep 4, Sep 18, Oct 2, Oct 30, Nov 13, Nov 27, Dec 11, Dec 25, 2028: Jan 8, Mar 4, Mar 18, Apr 15, Apr 29, May 27, Jun 10, Aug 19, Sep 2, Sep 16, More...
Seven Seas Mariner18 Night - Antarctic Encounter
Starting in Buenos Aires, Cruising the Atlantic Ocean, Port Stanley, Cruising the Atlantic Ocean, Cruising by Elephant Island (Cape Lookout), Cruising Admiralty Bay, Cruising the Drake Passage, Ushuaia, Punta Arenas, Cruising the Chilean Fjords, Puerto Montt, Cruising the Pacific Ocean, Santiago (San Antonio CL), Cruising the Pacific Ocean, Lima (Callao)
2027 Sails: Feb 20, More...
National Geographic Explorer Tours17 Night - Antarctica and Patagonia : Legendary Ice and Epic Fjords
Starting in Santiago, Chile or Buenos Aires, Argentina, Ushuaia, Argentina / Embark Ship, At Sea / Drake Passage, Antarctica, Chilean Fjords, Tierra del Fuego : Karukinka Natural Park and Ainsworth Bay, Francisco Coloane Marine Park, Kirke Narrows / Puerto Natales, Puerto Natales and Torres del Paine National Park, Puerto Natales / Disembark Ship / Santiago
2027 Sails: Feb 21, More...
Costa Serena9 Night - South America Roundtrip from Rio De Janeiro
Starting in Rio de Janeiro, Brazil, Baia De Copacabana, Ilhabela, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Camboriu, Brazil, Baia De Camboriu, Angra dos Reis, Rio de Janeiro, Brazil
2027 Sails: Feb 23, More...


South America Cruises