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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



Seabourn Tours, Seabourn Venture Tours
Seabourn Venture Tours11 Night - The Great White Continent - Tour An2
Starting in Buenos Aires, Argentina, Ushuaia, Argentina, Antarctica, Ushuaia, Argentina
2026 Sails: Dec 8, Dec 18, Dec 28, 2027: Jan 19, Feb 20, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa7 Night - South America
Starting in Maceio, Brazil, Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil
2026 Sails: Dec 9, Dec 16, 2027: Jan 6, Jan 13, Jan 20, Jan 27, Feb 3, Feb 10, Feb 17, Feb 24, Mar 3, Mar 10, Mar 17, Mar 24, More...
Silversea, Silver Cloud
Silver Cloud12 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, Drake Passage, Antarctic Sound, Antarctic Peninsula, South of the Polar Circle, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Dec 9, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Buenos Aires, Argentina, Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 10, Dec 17, 2027: Jan 14, Jan 21, Jan 28, Feb 4, Feb 11, Feb 18, Feb 25, More...
Norwegian Cruise Line, Norwegian Sun
Norwegian Sun11 Night - Panama Canal - Miami
Starting in Miami, Fl, Falmouth, Jamaica, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Dec 10, 2027: Jan 2, Mar 13, More...
Seabourn Tours, Seabourn Pursuit Tours
Seabourn Pursuit Tours11 Night - The Great White Continent - Tour An2
Starting in Buenos Aires, Argentina, Ushuaia, Argentina, Antarctica, Ushuaia, Argentina
2026 Sails: Dec 11, 2027: Jan 22, Feb 1, Feb 11, Feb 21, Mar 3, Mar 13, More...
Viking Ocean Tours, Viking Polaris Tours
Viking Polaris Tours12 Night - Antarctic Explorer
Starting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia
2026 Sails: Dec 11, Dec 22, 2027: Jan 2, Jan 13, Jan 24, Feb 4, Feb 15, Feb 26, Nov 12, Dec 17, Dec 28, 2028: Jan 8, Jan 19, Jan 30, Feb 10, Feb 21, Mar 3, Mar 14, Nov 22, 2029: Jan 2, Jan 13, Jan 24, Feb 21, Mar 4, More...
Silversea, Silver Wind
Silver Wind10 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, Drake Passage, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Dec 12, More...
Windstar, Star Legend
Star Legend8 Night - Panama Canal, Cartagena, San Blas Islands & More
Starting in Oranjestad, Cartagena CO, Bocas del Toro, San Blas, Panama, Panama Canal, Balboa / Fuerte Amador
2026 Sails: Dec 12, More...
Windstar, Star Legend
Star Legend16 Night - Star Collector : Latin America Explorer
Starting in Oranjestad, Cartagena CO, Bocas del Toro, San Blas, Panama, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Punta Leona, Costa Rica, Curu, Costa Rica, Playa Flamingo, Puerto Caldera
2026 Sails: Dec 12, More...

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South America Cruises