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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



Norwegian Cruise Line, Norwegian Sun
Norwegian Sun12 Night - Panama Canal - Miami
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Cabo Rojo, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Netherlands Antilles, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Miami, Fl
2026 Sails: Dec 21, 2027: Mar 1, More...
MSC Cruises, MSC Musica
MSC Musica7 Night - South America
Starting in Rio De Janeiro, Brazil, Ilha Grande, Brazil, Buzios, Brazil, Paranagua, Brazil, Itajai, Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil
2026 Sails: Dec 22, 2027: Jan 26, More...
MSC Cruises, MSC Splendida
MSC Splendida9 Night - South America
Starting in Rio De Janeiro, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Ilhabela, Brazil, Rio De Janeiro, Brazil
2026 Sails: Dec 22, More...
Princess Cruises, Majestic Princess
Majestic Princess15 Night - Cape Horn & Glaciers of Patagonia
Starting in Santiago (Valparaiso), Chile, Puerto Montt, Chile, Punta Arenas, Chile, Beagle Channel Fjords and Glacier Alley, Chile, Ushuaia (Tierra del Fuego), Argentina, Cape Horn (Scenic Cruising), Port Stanley, Falkland Islands, Puerto Madryn, Argentina, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 22, More...
Silversea, Silver Wind
Silver Wind15 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, South Georgia, Drake Passage, Elephant Island, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Dec 22, More...
Viking Ocean, Viking Sky
Viking Sky17 Night - Panama Canal & the Pacific Coast
Starting in Fort Lauderdale, Florida, Scenic Sailing Gulf of Mexico, Cozumel, Mexico, Sail the Caribbean Sea, Cartagena CO, Colon, Scenic Sailing Panama Canal, Sail the Pacific Ocean, Puntarenas (Puerto Caldera), Sail the Pacific Ocean, Cabo San Lucas, Sail the Pacific Ocean, Los Angeles, California
2026 Sails: Dec 22, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema7 Night - South America Roundtrip from Buenos Aires
Starting in Buenos Aires, Argentina, Montevideo, Uruguay, Itajai (Camboriu), Santos, Brazil, Buenos Aires, Argentina
2026 Sails: Dec 23, Dec 30, 2027: Jan 6, Jan 13, Jan 20, Jan 27, Feb 3, Feb 17, Feb 24, Mar 3, Mar 10, More...
MSC Cruises, MSC Poesia
MSC Poesia22 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2026 Sails: Dec 23, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa3 Night - South America
Starting in Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 23, 2027: Mar 31, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema7 Night - South America Roundtrip from Montevideo
Starting in Montevideo, Uruguay, Itajai, Brazil, Santos / Sao Paulo, Buenos Aires, Argentina, Montevideo, Uruguay
2026 Sails: Dec 24, 2027: Jan 7, Jan 14, Jan 21, Feb 4, Feb 18, Feb 25, Mar 4, Mar 11, More...

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South America Cruises