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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay



Viking Ocean Cruise Tours, Viking Octantis Cruise Tours
Viking Octantis Cruise Tours13 Night - Argentina & the Chilean Fjords
Starting in Buenos Aires, Ushuaia, Scenic Sailing : Cape Horn, Garibaldi Fjord, Chilean Glaciers, Punta Arenas, Scenic Sailing : Chilean Fjords, Chilean Glaciers, Scenic Sailing : Chilean Fjords, Puerto Chacabuco, Scenic Sailing : Chilean Fjords, Sail the Pacific Ocean, Santiago (Valparaiso)
2026 Sails: Mar 13, 2027: Mar 19, 2028: Mar 26, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship17 Night - Msc Grand Voyages
Starting in Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil, Mindelo, Cape Verde, Las Palmas de Gran Canaria (Canary Islands), Spain, Tangier (Tetouan), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy
2026 Sails: Mar 14, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship15 Night - Msc Grand Voyages
Starting in Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil, Mindelo, Cape Verde, Las Palmas de Gran Canaria (Canary Islands), Spain, Tangier (Tetouan), Morocco, Barcelona, Spain
2026 Sails: Mar 14, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship22 Night - Msc Grand Voyages
Starting in Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil, Mindelo, Cape Verde, Las Palmas de Gran Canaria (Canary Islands), Spain, Tangier (Tetouan), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy, Messina (Taormina), Italy, La Valletta, Malta, Split, Croatia, Venice / Marghera, Italy
2026 Sails: Mar 14, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship1 Night - Msc Grand Voyages
Starting in Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Mar 14, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship18 Night - Msc Grand Voyages
Starting in Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil, Mindelo, Cape Verde, Las Palmas de Gran Canaria (Canary Islands), Spain, Tangier (Tetouan), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy, Messina (Taormina), Italy
2026 Sails: Mar 14, More...
Norwegian Cruise Line (NCL), NCL Norwegian Breakaway
NCL Norwegian Breakaway Cruises8 Night - Bahamas - New York
Starting in New York City, Ny, Orlando Beaches / Port Canaveral, Fl, Great Stirrup Cay, Bahamas, Nassau, Bahamas, New York City, Ny
2026 Sails: Mar 14, More...
Royal Caribbean International (RCL), RCL Serenade of the Seas
RCL Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2026 Sails: Mar 14, Apr 11, More...
Azamara, Azamara Quest
Azamara Quest Cruise Ship11 Night - Panama Canal & Southern Caribbean Cruise : Cartagena, Aruba & Curacao
Starting in Panama City (Fuerte Amador), Panama Canal (Cruising), Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Kralendijk, Cabo Rojo, Miami, Florida
2026 Sails: Mar 15, More...
MSC Cruises, MSC Fantasia
MSC Fantasia Cruise Ship8 Night - South America
Starting in Buenos Aires, Argentina, Rio De Janeiro, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Mar 15, More...

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South America Cruises