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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



Holland America, Oosterdam
Oosterdam15 Night - South America Pathways : Chilean Fjords & Glaciers
Starting in San Antonio CL (Santiago), Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Daylight cruising Glacier Alley, Ushuaia, Argentina, Scenic Cruising Cape Horn, Port Stanley, Falkland Islands, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 4, More...
Norwegian Cruise Line, Norwegian Star
Norwegian Star16 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puntarenas / Puerto Caldera, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Dec 4, More...
PONANT, Le Lyrial
Le Lyrial17 Night - The Great Austral Loop
Starting in Ushuaia, Grave Cove, New Island, South Georgia, Antarctic Peninsula, Crossing the Drake Passage, Ushuaia
2026 Sails: Dec 4, More...
Silversea, Silver Wind
Silver Wind8 Night - King George Island to Puerto Williams
Starting in King George Island, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Dec 4, More...
Viking Ocean Tours, Viking Octantis Tours
Viking Octantis Tours12 Night - Antarctic Explorer
Starting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia
2026 Sails: Dec 4, Dec 15, Dec 26, 2027: Jan 6, Jan 17, Jan 28, Feb 8, Feb 19, More...
Windstar, Star Legend
Star Legend16 Night - Star Collector : Windward Islands & Spanish New World
Starting in Bridgetown, Rodney Bay, The Pitons, Scarborough, Tobago, Bequia, Mayreau, St Georges, Willemstad AN, Oranjestad, Cartagena CO, Bocas del Toro, San Blas, Panama, Panama Canal, Balboa / Fuerte Amador
2026 Sails: Dec 4, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox14 Night - Patagonia & Argentina Cruise
Starting in Buenos Aires, Argentina, Montevideo, Uruguay, Port Stanley, Falkland Islands, Cape Horn, Chile, Ushuaia, Argentina, Strait of Magellan, Punta Arenas, Chile, Puerto Madryn, Argentina, Punta Del Este, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 5, Dec 19, 2027: Feb 13, Feb 27, Dec 5, 2028: Feb 13, More...
MSC Cruises, MSC Seaview
MSC Seaview8 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Montevideo, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Dec 5, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 5, Dec 12, Dec 19, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, Mar 20, Mar 27, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil
2026 Sails: Dec 5, 2027: Jan 2, More...

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South America Cruises