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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Uruguay



Crystal Serenity15 Night - The Americas & Caribbean
Starting in San Diego, Cabo San Lucas (Baja California Sur), Mazatlan, Puerto Vallarta, Acajutla, Playa Flamingo, Puntarenas, Manta, Guayaquil, Salaverry, Lima (Callao)
2027 Sails: Jan 8, More...
Crystal Serenity139 Night - World Cruise
Starting in San Diego, Cabo San Lucas (Baja California Sur), Mazatlan, Puerto Vallarta, Acajutla, Playa Flamingo, Puntarenas, Manta, Guayaquil, Salaverry, Lima (Callao), Hanga Roa, Adamstown (Sightseeing Only), Rangiroa, Fakarava, Huahine, Papeete (Tahiti), Moorea Island, Raiatea, Bora Bora (Society Islands), Pago Pago, Date Line lose a day, Apia, Suva, Lautoka, Champagne Beach, Port Vila, Mystery Island, Anelghowhat, Lifou, Noumea, Bay of Islands, Auckland, Tauranga, Napier, Wellington, Lyttelton (Christchurch), Port Chalmers (Dunedin), Cruising Dusky Sound, Cruising Doubtful Sound, Cruising Milford Sound, Melbourne, Sydney AU, Newcastle AU, Brisbane, Airlie Beach, Cairns, Alotau, Port Moresby, Darwin, Komodo Island, Bali, Semarang (Gateway for Borobudur), Singapore, Koh Samui, Laem Chabang, Koh Kut, Phu Quoc, Ho Chi Minh City, Muara, Kota Kinabalu, Boracay, Manila, Hong Kong, Xiamen, Shanghai, Busan, Hiroshima, Beppu (Kyushu Island), Wakayama, Nagoya, Yokohama (Tokyo), Hitachinaka, Sendai, Hakodate (Hokkaido), Aomori, Kushiro, Date Line gain a day, Kodiak Island, Alaska, Seward, Cruise Hubbard Glacier, Alaska, Skagway, Alaska, Icy Strait Point, Alaska, Sitka, Alaska, Wrangell, Seymour Narrows, British Columbia, Vancouver
2027 Sails: Jan 8, More...
Nieuw Amsterdam21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2027 Sails: Jan 8, More...
National Geographic Endeavour II Tours16 Night - Ultimate Galapagos
Starting in Quito, Ecuador, Quito / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Quito, Quito
2027 Sails: Jan 8, Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, More...
MSC Splendida9 Night - South America
Starting in Rio De Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Itajai, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Rio De Janeiro, Brazil
2027 Sails: Jan 8, 2028: Jan 1, Jan 28, More...
Silver Cloud10 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, Drake Passage, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2027 Sails: Jan 8, Dec 20, 2028: Jan 11, Feb 8, More...
MS Roald Amundsen Tours11 Night - Highlights of Antarctica
Starting in Buenos Aires, Buenos Aires / Ezeiza Airport (International), Ushuaia Airport, Ushuaia, South Shetland, Northern Gerlache, Southern Gerlache, Northern Gerlache, Ushuaia, Ushuaia Airport
2027 Sails: Jan 9, Jan 19, Jan 29, Feb 8, More...
Silver Origin7 Night - San Cristobal to San Cristobal
Starting in San Cristobal, Galapagos, Kicker Rock, Isla Bartolome, Buccaneer Cove, Santiago, Punta Vicente Roca (Isabela), Punta Espinoza, Fernandina, Tagus Cove (Isabela), Elizabeth Bay (Isabela), Post Office Bay (Floreana), Champion Islet (Floreana), Punta Cormorant (Floreana), Santa Cruz Highlands, Fausto Llerena Breeding Center, Puerto Ayora, Cerro Dragon, Isla Guy Fawkes, Bahia Bowditch, San Cristobal, Galapagos
2027 Sails: Jan 9, Feb 6, Feb 20, Mar 6, Mar 20, Apr 17, May 15, Jun 12, Jun 26, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, Nov 27, Dec 25, 2028: Jan 8, Jan 22, Feb 5, Feb 19, Mar 4, Apr 1, More...
Costa Serena9 Night - South America Roundtrip from Rio De Janeiro
Starting in Rio de Janeiro, Brazil, Baia De Copacabana, Ilhabela, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Camboriu, Brazil, Camboriu Bay, Ilhabela, Brazil, Rio de Janeiro, Brazil
2027 Sails: Jan 10, More...
Queen Anne29 Night - Southampton to Rio De Janeiro
Starting in Southampton, England, UK, Hamilton, Bermuda, Port Canaveral, FL, Fort Lauderdale, FL, Grand Turk, Turks and Caicos Islands, Bridgetown, Barbados, Fortaleza, Brazil, Salvador, Brazil, Buzios, Brazil, Rio De Janeiro, Brazil
2027 Sails: Jan 10, More...


South America Cruises