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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



Seabourn Tours, Seabourn Pursuit Tours
Seabourn Pursuit Tours30 Night - Chilean Fjords, Antarctica, So - Tour N01
Starting in San Antonio CL (Santiago), Chile, Scenic Cruising Reloncavi Sound, Puerto Montt, Chile, Scenic cruising Moraleda Channel, Scenic cruising Darwin Channel, Scenic cruising Baker Channel, Caleta Tortel, Chile, Transit the English Narrows, Scenic cruising Eyre Fjord, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Wide Channel, Scenic cruising Peel Fjord, Brujo Glacier, Chile, Scenic cruising Smyth Channel, Strait of Magellan, Punta Arenas, Chile, Ushuaia, Argentina, Antarctica, South Georgia, The Falkland Islands, Ushuaia, Argentina, Buenos Aires
2026 Sails: Nov 12, More...
Viking Ocean, Viking Polaris
Viking Polaris12 Night - Chilean Fjords & Scenic Shores
Starting in Santiago (Valparaiso), Sail the Pacific Ocean, Scenic Sailing Chilean Fjords, Puerto Chacabuco, Scenic Sailing Chilean Fjords, Chilean Glaciers, Scenic Sailing Chilean Fjords, Punta Arenas, Chilean Glaciers, Garibaldi Fjord, Scenic Sailing Cape Horn, Ushuaia
2026 Sails: Nov 13, 2027: Nov 1, More...
Star Clippers, Royal Clipper
Royal Clipper14 Night - Panama to Antigua
Starting in Balboa (Isla Flamenco), Panama, Panama Canal Transit, San Blas Archipelago, Panama, Cartagena De Indias, Colombia, Santa Marta, Colombia, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, St Georges, Grenada, Soufriere, St Lucia, Deshaies, Guadeloupe, St Johns AG
2026 Sails: Nov 14, More...
MSC Cruises, MSC Divina
MSC Divina1 Night - Msc Grand Voyages
Starting in Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 15, More...
MSC Cruises, MSC Splendida
MSC Splendida18 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Gibraltar, Casablanca (Marrakesh), Morocco, Las Palmas de Gran Canaria (Canary Islands), Spain, Maceio, Brazil, Salvador, Brazil, Rio De Janeiro, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Nov 15, More...
MSC Cruises, MSC Splendida
MSC Splendida14 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Gibraltar, Casablanca (Marrakesh), Morocco, Las Palmas de Gran Canaria (Canary Islands), Spain, Maceio, Brazil, Salvador, Brazil, Rio De Janeiro, Brazil
2026 Sails: Nov 15, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa17 Night - Msc Grand Voyages
Starting in Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Santa Cruz de Tenerife, Las Palmas de Gran Canaria (Canary Islands), Spain, Salvador, Brazil, Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 15, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa16 Night - Msc Grand Voyages
Starting in Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Santa Cruz de Tenerife, Las Palmas de Gran Canaria (Canary Islands), Spain, Salvador, Brazil, Rio De Janeiro, Brazil
2026 Sails: Nov 15, More...
MSC Cruises, MSC Musica
MSC Musica4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 16, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa15 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Funchal (Madeira Islands), Portugal, Santa Cruz de Tenerife, Las Palmas de Gran Canaria (Canary Islands), Spain, Salvador, Brazil, Rio De Janeiro, Brazil
2026 Sails: Nov 16, More...

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South America Cruises