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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Suriname : Uruguay



MSC Cruises, MSC Fantasia
MSC Fantasia Cruise Ship9 Night - South America
Starting in Buenos Aires, Argentina, Rio De Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Itajai, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Feb 17, More...
Regent Seven Seas Cruises, Seven Seas Splendor
Seven Seas Splendor Cruises24 Night - The Colors of Carnival
Starting in Buenos Aires, Punta Del Este, Rio Grande, Cruising the Coast of Brazil, Porto Belo, Santos, Ilha Grande, Brazil, Rio De Janeiro, Buzios, Brazil, Cruising the Coast of Brazil, Salvador, Maceio, Recife, Cruising the Coast of Brazil, Belem (Icoaraci), Cruising the Atlantic Ocean, Devils Island, Cruising the Atlantic Ocean, Castries, Roseau, Philipsburg, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami
2026 Sails: Feb 17, More...
Azamara, Azamara Quest
Azamara Quest Cruise Ship10 Night - Chile Intensive Cruise : Punta Arenas, Chilean Fjords & San Antonio
Starting in Ushuaia, Sailing in the Beagle Channel, Ushuaia, Punta Arenas, Sailing in the Chilean Fjords, Puerto Chacabuco, Castro, Puerto Montt, San Antonio Cl
2026 Sails: Feb 20, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia Cruise Ship4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Feb 20, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa Cruise Ship8 Night - South America Roundtrip from Rio De Janeiro
Starting in Rio de Janeiro, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Camboriu, Brazil, Ilhabela, Brazil, Rio de Janeiro, Brazil
2026 Sails: Feb 21, More...
Oceania Cruises, Oceania Vista
Oceania Vista Cruises14 Night - Inca & Aztec Kingdoms
Starting in Lima / Machu Picchu (Callao), Salaverry, Manta, Puntarenas, Acajutla, Acapulco, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Feb 21, More...
Royal Caribbean International (RCL), RCL Serenade of the Seas
RCL Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama
2026 Sails: Feb 21, Feb 28, More...
Viking Ocean Cruise Tours, Viking Polaris Cruise Tours
Viking Polaris Cruise Tours12 Night - Antarctic Explorer
Starting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia
2026 Sails: Feb 21, More...
Holland America Line (HAL), HAL Oosterdam
HAL Oosterdam Cruise Ship14 Night - South America Passage
Starting in San Antonio CL (Santiago), Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Daylight cruising Glacier Alley, Ushuaia, Argentina, Scenic Cruising Cape Horn, Port Stanley, Falkland Islands, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Feb 22, More...
MSC Cruises, MSC Divina
MSC Divina Cruises18 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocean Cay Msc Marine Reserve, Bahamas, Cozumel, Mexico, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Feb 22, More...

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South America Cruises