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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



Scenic Luxury, Scenic Eclipse
Scenic Eclipse15 Night - Antarctica and the Weddell Sea
Starting in Buenos Aires, Buenos Aires / Ushuaia, Antarctica, At Sea / Ushuaia, Ushuaia, Argentina / Buenos Aires
2026 Sails: Dec 3, More...
Norwegian Cruise Line, Norwegian Star
Norwegian Star16 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puntarenas / Puerto Caldera, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Dec 4, More...
Silversea, Silver Wind
Silver Wind8 Night - King George Island to Puerto Williams
Starting in King George Island, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Dec 4, More...
Windstar, Star Legend
Star Legend16 Night - Star Collector : Windward Islands & Spanish New World
Starting in Bridgetown, Barbados, Rodney Bay, Sunset Cruising Pitons, Scarborough, Tobago, Bequia, Mayreau, St Georges, Grenada, Willemstad AN, Curacao, Oranjestad, Aruba, Cartagena CO, Bocas del Toro, San Blas Islands, Panama, Panama Canal Transit, Fuerte Amador, Panama City
2026 Sails: Dec 4, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox14 Night - Patagonia & Argentina Cruise
Starting in Buenos Aires, Argentina, Montevideo, Uruguay, Port Stanley, Falkland Islands, Cape Horn, Chile, Ushuaia, Argentina, Strait of Magellan, Punta Arenas, Chile, Puerto Madryn, Argentina, Punta Del Este, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 5, Dec 19, 2027: Feb 13, Feb 27, Dec 5, 2028: Feb 13, More...
MSC Cruises, MSC Seaview
MSC Seaview8 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Montevideo, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Dec 5, More...
MSC Cruises, MSC Seaview
MSC Seaview5 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 5, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil
2026 Sails: Dec 5, 2027: Jan 2, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil
2026 Sails: Dec 5, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 5, Dec 12, Dec 19, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, Mar 20, Mar 27, Dec 4, Dec 11, 2028: Jan 8, Jan 15, Jan 22, Jan 29, Feb 5, Feb 12, More...

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South America Cruises