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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Uruguay



Silver Endeavour13 Night - King George Island to Puerto Williams
Starting in King George Island, Antarctic Sound, Antarctic Peninsula, Drake Passage, Carcass Islands, Falklands, New Island, Port Stanley, Falkland Islands, Puerto Williams
2027 Sails: Jan 2, More...
AmaMelodia Tours13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...
AmaMelodia Tours10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...
World Traveller18 Night - Ushuaia Roundtrip
Starting in Ushuaia, Drake Passage Navigation, Antarctic Peninsula / Captains Choice, South Georgia / Captains Choice, Port Stanley, Falkland Islands, Saunders Island, Falkland Islands / Captains Choice, Carcass Island, Falkland Islands / Captains Choice, Ushuaia
2027 Sails: Jan 3, More...
Zaandam70 Night - Grand South America & Antarctica Voyage
Starting in Fort Lauderdale, Florida, Georgetown, Cayman Islands, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile, Isla Robinson Crusoe, Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Scenic Cruising Glacier Alley, Scenic Cruising Cape Horn, Ushuaia, Argentina, Antarctic, Port Stanley, Falkland Islands, Puerto Madryn, Argentina, Punta Del Este, Uruguay, Montevideo, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil, Abraao, Ilha Grande, Brazil, Rio De Janeiro, Brazil, Salvador da Bahia, Brazil, Recife, Brazil, Fortaleza, Brazil, Icoaraci (Belem), Brazil, Crossing the Equator, Devils Island, French Guiana, Bridgetown, Barbados, Castries, Saint Lucia, Basseterre, St Kitts and Nevis, San Juan, Puerto Rico, Fort Lauderdale, Florida
2027 Sails: Jan 3, More...
Zaandam41 Night - Grand South America & Antarctica Voyage
Starting in Fort Lauderdale, Florida, Georgetown, Cayman Islands, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile, Isla Robinson Crusoe, Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Scenic Cruising Glacier Alley, Scenic Cruising Cape Horn, Ushuaia, Argentina, Antarctic, Port Stanley, Falkland Islands, Puerto Madryn, Argentina, Punta Del Este, Uruguay, Montevideo, Uruguay, Buenos Aires, Argentina
2027 Sails: Jan 3, More...
MSC Musica7 Night - South America
Starting in Itajai, Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil, Buzios, Brazil, Ilha Grande, Brazil, Paranagua, Brazil, Itajai, Brazil
2027 Sails: Jan 3, Jan 10, Jan 17, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, 2028: Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, More...
MSC Poesia11 Night - Caribbean and Antilles
Starting in Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2027 Sails: Jan 3, Jan 24, 2028: Jan 23, More...
Oceania Insignia21 Night - Patagonian Panorama
Starting in Lima / Machu Picchu (Callao), Pisco / Nazca Lines, Coquimbo, Santiago De Chile (San Antonio CL), Puerto Montt, Puerto Chacabuco, Laguna San Raphael, Cruising the Chilean Fjords, Punta Arenas, Cruising Around Cape Horn, Ushuaia, Port Stanley, Falkland Islands, Puerto Madryn, Punta Del Este, Buenos Aires
2027 Sails: Jan 3, More...
Carnival Firenze15 Night - Journeys - South America
Starting in Long Beach (Los Angeles), Ca, Acapulco, Mexico, Crossing the Equator, Manta, Ecuador, Callao (Lima), Peru, Coquimbo (La Serena), Chile, Valparaiso (Santiago), Chile
2027 Sails: Jan 4, More...


South America Cruises