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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



MSC Cruises, MSC Divina
MSC Divina16 Night - Msc Grand Voyages
Starting in Genoa (Portofino), Italy, Tarragona, Spain, Santa Cruz de Tenerife, Salvador, Brazil, Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Oct 31, More...
MSC Cruises, MSC Divina
MSC Divina15 Night - Msc Grand Voyages
Starting in Genoa (Portofino), Italy, Tarragona, Spain, Santa Cruz de Tenerife, Salvador, Brazil, Rio De Janeiro, Brazil
2026 Sails: Oct 31, More...
Star Clippers, Royal Clipper
Royal Clipper14 Night - Barbados to Panama
Starting in Bridgetown, Barbados, Soufriere, St Lucia, Tobago Cays, Grenadines, St Georges, Grenada, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, Santa Marta, Colombia, Cartagena De Indias, Colombia, San Blas Archipelago, Panama, Panama Canal Transit, Balboa (Isla Flamenco), Panama
2026 Sails: Oct 31, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema21 Night - Transatlantic from Marseille
Starting in Marseille, Savona, Barcelona, Malaga, Cadice, Lisbon, Las Palmas, Santa Cruz de Tenerife, St Vincent / Cape Verde / Mindelo, Maceio, Salvador Bahia, Rio De Janeiro
2026 Sails: Nov 1, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema22 Night - Transatlantic from Marseille
Starting in Marseille, Savona, Barcelona, Malaga, Cadice, Lisbon, Las Palmas, Santa Cruz de Tenerife, St Vincent / Cape Verde / Mindelo, Maceio, Salvador Bahia, Rio De Janeiro, Santos
2026 Sails: Nov 1, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema24 Night - Southern Europe from Marseille to Itajai
Starting in Marseille, Savona, Barcelona, Malaga, Cadice, Lisbon, Las Palmas, Santa Cruz de Tenerife, St Vincent / Cape Verde / Mindelo, Maceio, Salvador Bahia, Rio De Janeiro, Santos, Itajai
2026 Sails: Nov 1, More...
MSC Cruises, MSC Poesia
MSC Poesia11 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colombia, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2026 Sails: Nov 1, More...
MSC Cruises, MSC Poesia
MSC Poesia21 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Roatan Island, Honduras, Belize City, Belize, Miami, Florida, Charlotte Amalie (St Thomas) Virgin Islands, Basseterre, St Kitts and Nevis, Philipsburg, St Maarten, St Johns AG, Antigua, San Juan Porto Rico, Puerto Plata, Dominican Republic, Miami, Florida
2026 Sails: Nov 1, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema21 Night - Transatlantic from Savona
Starting in Savona, Barcelona, Malaga, Cadice, Lisbon, Las Palmas, Santa Cruz de Tenerife, St Vincent / Cape Verde / Mindelo, Maceio, Salvador Bahia, Rio De Janeiro, Santos
2026 Sails: Nov 2, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema20 Night - Transatlantic from Savona
Starting in Savona, Barcelona, Malaga, Cadice, Lisbon, Las Palmas, Santa Cruz de Tenerife, St Vincent / Cape Verde / Mindelo, Maceio, Salvador Bahia, Rio De Janeiro
2026 Sails: Nov 2, More...

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South America Cruises