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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Uruguay



MSC Cruises, MSC Divina
MSC Divina5 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Buzios, Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 21, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil, Camboriu, Brazil
2026 Sails: Dec 21, Dec 28, More...
Norwegian Cruise Line, Norwegian Sun
Norwegian Sun12 Night - Panama Canal - Miami
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Cabo Rojo, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Netherlands Antilles, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Miami, Fl
2026 Sails: Dec 21, 2027: Mar 1, More...
MSC Cruises, MSC Musica
MSC Musica7 Night - South America
Starting in Rio De Janeiro, Brazil, Ilha Grande, Brazil, Buzios, Brazil, Paranagua, Brazil, Itajai, Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil
2026 Sails: Dec 22, 2027: Jan 26, More...
MSC Cruises, MSC Splendida
MSC Splendida9 Night - South America
Starting in Rio De Janeiro, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Ilhabela, Brazil, Rio De Janeiro, Brazil
2026 Sails: Dec 22, More...
Princess Cruises, Majestic Princess
Majestic Princess15 Night - Cape Horn & Glaciers of Patagonia
Starting in Santiago (Valparaiso), Chile, Puerto Montt, Chile, Punta Arenas, Chile, Beagle Channel Fjords and Glacier Alley, Chile, Ushuaia (Tierra del Fuego), Argentina, Cape Horn (Scenic Cruising), Port Stanley, Falkland Islands, Puerto Madryn, Argentina, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 22, More...
Scenic Luxury, Scenic Eclipse II
Scenic Eclipse II15 Night - Antarctica and the Weddell Sea
Starting in Buenos Aires, Buenos Aires / Ushuaia, Antarctica, At Sea / Ushuaia, Ushuaia, Argentina / Buenos Aires
2026 Sails: Dec 22, More...
Silversea, Silver Wind
Silver Wind15 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, South Georgia, Drake Passage, Elephant Island, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Dec 22, More...
Viking Ocean, Viking Sky
Viking Sky17 Night - Panama Canal & the Pacific Coast
Starting in Fort Lauderdale, Florida, Scenic Sailing Gulf of Mexico, Cozumel, Mexico, Sail the Caribbean Sea, Cartagena CO, Colon, Scenic Sailing Panama Canal, Sail the Pacific Ocean, Puntarenas (Puerto Caldera), Sail the Pacific Ocean, Cabo San Lucas, Sail the Pacific Ocean, Los Angeles, California
2026 Sails: Dec 22, More...
Viking Ocean Tours, Viking Polaris Tours
Viking Polaris Tours12 Night - Antarctic Explorer
Starting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia
2026 Sails: Dec 22, 2027: Jan 13, Jan 24, Feb 4, Feb 15, Feb 26, Nov 12, Dec 17, Dec 28, 2028: Jan 8, Jan 19, Jan 30, Feb 10, Feb 21, Mar 3, Mar 14, Nov 22, 2029: Jan 2, Jan 13, Jan 24, Feb 21, Mar 4, More...

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South America Cruises