Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Suriname : Uruguay



Costa Cruise Lines, Costa Favolosa
Costa Favolosa Cruise Ship9 Night - South America Roundtrip from Rio De Janeiro
Starting in Rio de Janeiro, Brazil, Abraao (Ilha Grande), Buenos Aires, Argentina, Montevideo, Uruguay, Camboriu, Brazil, Ilhabela, Brazil, Rio de Janeiro, Brazil
2026 Sails: Feb 4, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship7 Night - South America
Starting in Salvador, Brazil, Ilheus, Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Salvador, Brazil
2026 Sails: Feb 4, Feb 11, More...
Lindblad Expeditions Cruise Tours, Delfin III Cruise Tours
Delfin III Cruises9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Feb 5, Feb 12, Mar 5, Apr 23, May 21, Jun 4, Jul 23, Aug 13, Aug 20, Sep 10, Nov 5, Nov 26, Dec 3, More...
Silversea Cruises, Silver Endeavour
Silver Endeavour Cruises10 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, Drake Passage, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Feb 5, Mar 5, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia Cruise Ship4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Feb 6, More...
Swan Hellenic Cruises, SH Vega
SH Vega Cruises17 Night - In Shackleton's Footsteps
Starting in Ushuaia, West Point Island, Saunders Island, Port Stanley, Falkland Islands, South Georgia, Antarctic Peninsula, Ushuaia
2026 Sails: Feb 6, More...
AmaWaterways, AmaMagdalena
AmaMagdalena Cruises7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: Feb 7, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 30, Jun 27, Jul 11, Aug 22, Sep 5, Oct 3, Oct 17, Nov 14, Nov 28, Dec 12, More...
Lindblad Expeditions Cruise Tours, National Geographic Endurance Cruise Tours
National Geographic Endurance Cruises21 Night - Antarctica, South Georgia, and the Falklands
Starting in Buenos Aires, Argentina, or Santiago, Chile, Ushuaia, Argentina / EmbarkShip, Antarctica, South Georgia Island, Falkland Islands, Disembark Ship / Ushuaia / Buenos Aires or Santiago
2026 Sails: Feb 7, Nov 12, 2027: Feb 8, 2028: Feb 17, More...
MSC Cruises, MSC Fantasia
MSC Fantasia Cruise Ship9 Night - South America
Starting in Montevideo, Uruguay, Buenos Aires, Argentina, Rio De Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Montevideo, Uruguay
2026 Sails: Feb 7, More...
MSC Cruises, MSC Seaview
MSC Seaview Cruises7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Feb 7, Feb 14, More...

<= Back
More =>

South America Cruises