Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Suriname : Uruguay



Costa Cruise Lines, Costa Diadema
Costa Diadema Cruises7 Night - South America Roundtrip from Itajai
Starting in Itajai, Brazil, Santos, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil
2026 Sails: Jan 24, Jan 31, Feb 14, Feb 28, Mar 7, Mar 14, Mar 21, More...
Holland America Line (HAL), HAL Zuiderdam
HAL Zuiderdam Cruise Ship22 Night - Eastern Caribbean & Panama Canal
Starting in Miami, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 24, More...
MSC Cruises, MSC Seaview
MSC Seaview Cruises7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Jan 24, Mar 14, More...
Oceania Cruises, Oceania Vista
Oceania Vista Cruises10 Night - Brazilian Rhythms
Starting in Rio De Janeiro, Ilha Grande, Brazil, Sao Paulo (Santos), Porto Belo, Rio Grande, Punta Del Este, Montevideo, Buenos Aires
2026 Sails: Jan 24, More...
Ritz-Carlton Yacht Collection, Evrima
Evrima Cruises8 Night - Aruba / Aruba
Starting in Aruba, Cartagena CO, Santa Marta, Willemstad AN, Kralendijk, Aruba
2026 Sails: Jan 24, More...
Royal Caribbean International (RCL), RCL Serenade of the Seas
RCL Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama
2026 Sails: Jan 24, Jan 31, Feb 7, More...
Silversea Cruises, Silver Endeavour
Silver Endeavour Cruises12 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, Drake Passage, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Jan 24, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema Cruises7 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil, Santos, Brazil
2026 Sails: Jan 25, Feb 1, Feb 15, Mar 1, Mar 8, Mar 15, Mar 22, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Jan 25, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa Cruises7 Night - South Caribbean
Starting in Pointe-A-Pitre, Guadeloupe, Road Town (Tortola), British Virgin Islands, Philipsburg, St Maarten, Basseterre, Sao Cristovao, Nevis, St Johns AG, Antigua, Fort-de-France, Martinique, Pointe-A-Pitre, Guadeloupe
2026 Sails: Jan 25, More...

<= Back
More =>

South America Cruises