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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay



Lindblad Expeditions Cruise Tours, National Geographic Endurance Cruise Tours
National Geographic Endurance Cruises11 Night - Voyage to Antarctica
Starting in Buenos Aires, Argentina or Santiago, Chile, Fly to Ushuaia, Argentina / Embark Ship, At Sea Crossing the Drake Passage, Antarctica, Ushuaia / Disembark Ship / Buenos Aires or Santiago
2025 Sails: Dec 9, Dec 19, Dec 29, 2026: Jan 8, Jan 18, Jan 28, Dec 2, Dec 12, Dec 22, 2027: Jan 1, Nov 15, Nov 25, Dec 19, Dec 29, 2028: Jan 8, Jan 18, Jan 28, Feb 7, More...
MSC Cruises, MSC Fantasia
MSC Fantasia Cruise Ship8 Night - South America
Starting in Montevideo, Uruguay, Buenos Aires, Argentina, Rio De Janeiro, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Montevideo, Uruguay
2025 Sails: Dec 9, Dec 17, More...
MSC Cruises, MSC Seaview
MSC Seaview Cruises7 Night - South America
Starting in Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil
2025 Sails: Dec 9, More...
Quark Expeditions Cruise Tours, World Explorer Cruise Tours
World Explorer Cruise Tours7 Night - Antarctic Express : Fly the Drake
Starting in Arrive in Punta Arenas, Chile, Fly to King George Island and Embarkation, Antarctic Peninsula and South Shetland Islands, Disembarkation and Fly to Punta Arenas, Depart Punta Arenas
2025 Sails: Dec 10, Dec 15, More...
Scenic Luxury Cruises, Scenic Eclipse
Scenic Eclipse Cruises12 Night - Antarctica in Depth
Starting in Buenos Aires, Argentina, Buenos Aires / Ushuaia, Antarctica, At Sea / Ushuaia, Ushuaia, Argentina / Buenos Aires
2025 Sails: Dec 10, 2026: Feb 13, 2027: Jan 26, Feb 6, Feb 17, More...
Silversea Cruises, Silver Shadow
Silver Shadow Cruise Ship9 Night - Bridgetown to Cartagena
Starting in Bridgetown, Rodney Bay, Canouan, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, Santa Marta, Cartagena CO
2025 Sails: Dec 10, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship3 Night - Msc Grand Voyages
Starting in Salvador, Brazil, Buzios, Brazil, Rio De Janeiro, Brazil
2025 Sails: Dec 11, More...
Silversea Cruises, Silver Wind
Silver Wind Cruise Ship10 Night - Puerto Williams to Puerto Williams
Starting in Puerto Williams, Drake Passage, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2025 Sails: Dec 11, 2026: Feb 22, Dec 12, More...
AmaWaterways Cruise Tours, AmaMelodia Cruise Tours
AmaMelodia Cruise Tours12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2025 Sails: Dec 12, 2026: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 2, Oct 30, Nov 13, Nov 27, Dec 11, More...
Norwegian Cruise Line (NCL), NCL Norwegian Breakaway
NCL Norwegian Breakaway Cruises11 Night - Southern Caribbean - New York
Starting in New York City, Ny, Tortola, British Virgin Islands, Basseterre, Saint Kitts / Nevis, St Thomas, Vi, San Juan, Pr, Puerto Plata, Dominican Republic, New York City, Ny
2025 Sails: Dec 12, More...

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South America Cruises