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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay



PONANT, Le Dumont-D'Urville
Le Dumont-D'Urville Cruises12 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, Portobelo, San Blas Islands, Cartagena CO, Santa Marta, Willemstad AN, Mayreau Island, Union Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2026 Sails: Jan 16, More...
AmaWaterways, AmaMagdalena
AmaMagdalena Cruises7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Jan 17, Feb 28, Mar 28, Apr 11, Apr 25, May 9, Jun 6, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema Cruises7 Night - South America Roundtrip from Itajai
Starting in Itajai, Brazil, Santos, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil
2026 Sails: Jan 17, Feb 21, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship7 Night - South America
Starting in Rio De Janeiro, Brazil, Maceio, Brazil, Salvador, Brazil, Ilheus, Brazil, Rio De Janeiro, Brazil
2026 Sails: Jan 17, Jan 24, Feb 14, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises8 Night - South America
Starting in Santos (Sao Paulo), Brazil, Montevideo, Uruguay, Buenos Aires, Argentina, Punta Del Este, Uruguay, Camboriu, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Jan 17, More...
MSC Cruises, MSC Seaview
MSC Seaview Cruises7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Jan 17, Jan 24, Jan 31, Feb 7, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4, More...
Oceania Cruises, Oceania Nautica
Oceania Nautica Cruise Ship20 Night - Caribbean Kaleidoscope
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Cartagena CO, Kralendijk, Willemstad AN, Oranjestad, Port Antonio, Miami
2026 Sails: Jan 17, More...
Quark Expeditions Cruise Tours, Ocean Explorer Cruise Tours
Ocean Explorer Cruise Tours9 Night - Antarctic Express : Fly South, Sail North
Starting in Punta Arenas, Chile, Embarkation Day, Antarctic Peninsula and South Shetland Islands, Crossing the Drake Passage to Ushuaia, Disembark and overnight in Ushuaia, Argentina, Depart for Home
2026 Sails: Jan 17, Mar 13, More...
Windstar Cruises, Star Pride
Star Pride Cruises8 Night - Panama Canal, Cartagena, San Blas Islands & More
Starting in Oranjestad, Cartagena CO, Bocas del Toro, San Blas, Panama, Panama Canal, Balboa / Fuerte Amador
2026 Sails: Jan 17, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema Cruises7 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil, Santos, Brazil
2026 Sails: Jan 18, Feb 22, More...

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South America Cruises