Central America Cruises

Cruises that visit Central America

Cruises by region

Click on a cruise ship itinerary in Central America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Central America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Belize : Costa Rica : El Salvador : Guatemala : Honduras : Nicaragua : Panama

Cunard Line, Queen Elizabeth

21 Night - Caribbean Roundtrip from Miami
Starting in Miami, FL, Grand Cayman, Cayman Islands, Montego Bay, Jamaica, Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Miami, FL, St Thomas, US Virgin Islands, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2025 Sails: Dec 30, More...

MSC Cruises, MSC Seashore

7 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Cozumel, Mexico, Belize City, Belize, Isla De Roatan, Honduras, Port Canaveral (Orlando), Florida
2026 Sails: Jan 2, More...

Norwegian Cruise Line (NCL), NCL Norwegian Pearl

11 Night - Panama Canal - Miami
Starting in Miami, Fl, Ocho Rios, Jamaica, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Jan 2, More...

PONANT, Le Dumont-D'Urville

7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2026 Sails: Jan 2, More...

Holland America Line (HAL), HAL Koningsdam

21 Night - Eastern & Western Caribbean : Leeward Islands & Mexico
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, St Thomas, US Virgin Islands, St Johns AG, Antigua, Fort-De-France, Martinique, Roseau, Dominica, Basseterre, St Kitts and Nevis, Philipsburg, Sint Maarten, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Falmouth, Jamaica, Georgetown, Cayman Islands, Belize City, Belize, Coxen Hole, Roatan, Honduras, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Jan 3, More...

MSC Cruises, MSC World America

14 Night - Caribbean and Antilles
Starting in Miami, Florida, Isla De Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Puerto Plata, Dominican Republic, San Juan Porto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Jan 3, More...

Norwegian Cruise Line (NCL), NCL Norwegian Encore

7 Night - Western Caribbean - Miami
Starting in Miami, Fl, Roatan Bay Islands, Honduras, Belize City, Belize, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Jan 3, More...

Norwegian Cruise Line (NCL), NCL Norwegian Viva

7 Night - Caribbean
Starting in Galveston, Texas, Cozumel, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Galveston, Texas
2026 Sails: Jan 3, More...

Regent Seven Seas Cruises, Seven Seas Grandeur

22 Night - Tropical Escape Across the Canal
Starting in Miami, Cruising the Florida Straits, George Town, Ocho Rios, Jamaica, Cruising the Caribbean Sea, Bonaire (Kralendijk), Willemstad AN, Oranjestad, Cartagena CO, Cruising the Caribbean Sea, Puerto Limon, Panama Canal Transit, Panama City, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Vallarta, Cabo San Lucas, Cruising the Pacific Ocean, Ensenada, Los Angeles
2026 Sails: Jan 3, More...

Regent Seven Seas Cruises, Seven Seas Mariner

7 Night - Lush Islands, Lovely Shores
Starting in Miami, Cruising the Florida Straits, Cozumel, Mexico, Roatan, Harvest Caye, Costa Maya, Mexico, Cruising the Florida Straits, Miami
2026 Sails: Jan 3, More...

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