Guatemala Cruises
Cruises that visit Central America: Guatemala
Related areas: Puerto Quetzal : Santo Tomas de Castilla
20 Night - Caribbean Kaleidoscope
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Cartagena CO, Kralendijk, Willemstad AN, Oranjestad, Port Antonio, Miami
2026 Sails: Jan 17, More...10 Night - Passage to Panama
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City
2026 Sails: Jan 17, More...
22 Night - Eastern Caribbean & Panama Canal
Starting in Miami, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 24, More...
16 Night - Stars & Salsa
Starting in Los Angeles, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Panama Canal Transit, Cartagena CO, Cruising the Caribbean Sea, George Town, Cruising the Florida Straits, Miami
2026 Sails: Jan 25, More...
12 Night - Mesoamerican Majesty
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Roatan, Santo Tomas, Belize City, Montego Bay, George Town, Miami
2026 Sails: Jan 28, More...27 Night - Panama Canal & Historic Sea of Cortez
Starting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 31, More...15 Night - Panama Canal
Starting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 31, More...27 Night - Historic Sea of Cortez & Panama Canal
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 15, More...
62 Night - Hong Kong to Southampton
Starting in Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia, Port Vila, Vanuatu, Suva, Fiji, Cross International Date Line (Cruise-by), Honolulu, HI, Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Feb 27, More...26 Night - Panama Canal & Eastern Caribbean
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Fort-De-France, Martinique, Roseau, Dominica, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 27, More...
Cruises that visit Central America: Guatemala
Click on a cruise ship itinerary that visits Guatemala (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Guatemala), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Puerto Quetzal : Santo Tomas de Castilla
20 Night - Caribbean KaleidoscopeStarting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Cartagena CO, Kralendijk, Willemstad AN, Oranjestad, Port Antonio, Miami
2026 Sails: Jan 17, More...
10 Night - Passage to PanamaStarting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City
2026 Sails: Jan 17, More...
22 Night - Eastern Caribbean & Panama CanalStarting in Miami, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 24, More...
16 Night - Stars & SalsaStarting in Los Angeles, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Panama Canal Transit, Cartagena CO, Cruising the Caribbean Sea, George Town, Cruising the Florida Straits, Miami
2026 Sails: Jan 25, More...
12 Night - Mesoamerican MajestyStarting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Roatan, Santo Tomas, Belize City, Montego Bay, George Town, Miami
2026 Sails: Jan 28, More...
27 Night - Panama Canal & Historic Sea of CortezStarting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 31, More...
15 Night - Panama CanalStarting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 31, More...
27 Night - Historic Sea of Cortez & Panama CanalStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 15, More...
62 Night - Hong Kong to SouthamptonStarting in Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia, Port Vila, Vanuatu, Suva, Fiji, Cross International Date Line (Cruise-by), Honolulu, HI, Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Feb 27, More...
26 Night - Panama Canal & Eastern CaribbeanStarting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Fort-De-France, Martinique, Roseau, Dominica, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 27, More...
