Central America Cruises
Cruises that visit Central America
Cruises by region
See all Central America River Cruises
Related areas: Belize : Costa Rica : El Salvador : Guatemala : Honduras : Nicaragua : Panama
16 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 20, Dec 28, 2027: Mar 2, Apr 3, More...
26 Night - Alaska
Starting in Seattle, Washington, Ketchikan, Alaska, Sitka, Alaska, Endicott Arm and Dawes Glacier, Juneau, Alaska, Victoria CA, Canada, Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Sep 21, More...
22 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, San Francisco, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 23, More...
21 Night - Seattle to Miami
Starting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Sep 24, More...33 Night - Seattle to Miami
Starting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2026 Sails: Sep 24, More...
16 Night - Journeys - Panama Canal
Starting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2026 Sails: Sep 26, More...
14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Amber Cove, Dominican Republic, San Juan, Puerto Rico, St Maarten, Fort Lauderdale, Florida, Roatan (Mahogany Bay, Honduras), Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Sep 26, More...
6 Night - Western Caribbean
Starting in Galveston, Tx, Cozumel, Mexico, Isla Tropicale, Roatan, Galveston, Tx
2026 Sails: Sep 27, Oct 11, Oct 25, Nov 8, Nov 22, Dec 6, Dec 12, 2027: Jan 3, Jan 17, Jan 31, Feb 14, Feb 28, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, More...
21 Night - Panama Canal
Starting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
Cruises that visit Central America
Cruises by region
See all Central America River Cruises
Click on a cruise ship itinerary in Central America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Central America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Belize : Costa Rica : El Salvador : Guatemala : Honduras : Nicaragua : Panama
16 Night - Panama Canal - Ocean to OceanStarting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 20, Dec 28, 2027: Mar 2, Apr 3, More...
26 Night - AlaskaStarting in Seattle, Washington, Ketchikan, Alaska, Sitka, Alaska, Endicott Arm and Dawes Glacier, Juneau, Alaska, Victoria CA, Canada, Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Sep 21, More...
22 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, San Francisco, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 23, More...
21 Night - Seattle to MiamiStarting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Sep 24, More...
33 Night - Seattle to MiamiStarting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2026 Sails: Sep 24, More...
16 Night - Journeys - Panama CanalStarting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2026 Sails: Sep 26, More...
14 Night - Eastern / Western Caribbean AdventurerStarting in Fort Lauderdale, Florida, Amber Cove, Dominican Republic, San Juan, Puerto Rico, St Maarten, Fort Lauderdale, Florida, Roatan (Mahogany Bay, Honduras), Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Sep 26, More...
6 Night - Western CaribbeanStarting in Galveston, Tx, Cozumel, Mexico, Isla Tropicale, Roatan, Galveston, Tx
2026 Sails: Sep 27, Oct 11, Oct 25, Nov 8, Nov 22, Dec 6, Dec 12, 2027: Jan 3, Jan 17, Jan 31, Feb 14, Feb 28, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, More...
21 Night - Panama CanalStarting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
23 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
