Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Costa Cruise Lines, Costa Pacifica

7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Nov 10, More...

PONANT, Le Bougainville

5 Night - Andalusia and Moroccan Shores
Starting in Malaga, Gibraltar, Cadiz, Tangier, Melilla, Malaga
2026 Sails: Nov 10, Nov 15, More...

Costa Cruise Lines, Costa Diadema

12 Night - Transatlantic from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, St Vincent / Cape Verde / Mindelo, Maceio, Salvador Bahia, Rio De Janeiro, Santos
2026 Sails: Nov 11, More...

Costa Cruise Lines, Costa Diadema

11 Night - Transatlantic from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, St Vincent / Cape Verde / Mindelo, Maceio, Salvador Bahia, Rio De Janeiro
2026 Sails: Nov 11, More...

Regent Seven Seas, Seven Seas Navigator

12 Night - Spanish & Moroccan Delights
Starting in Barcelona, Alicante, Cruising the Mediterranean Sea, Malaga, Gibraltar, Casablanca, Agadir, Arrecife (Lanzarote), Santa Cruz de Tenerife, Funchal (Madeira), Cruising the Atlantic Ocean, Lisbon
2026 Sails: Nov 11, More...

Viking Ocean, Viking Jupiter

21 Night - Southern Atlantic Crossing
Starting in Barcelona, Sail the Mediterranean Sea, Granada (Malaga), Casablanca, Sail the Atlantic Ocean, Sao Vicente Island (Mindelo), Sail the Atlantic Ocean, Recife, Sail the South Atlantic Ocean, Rio De Janeiro, Sail the South Atlantic Ocean, Montevideo, Buenos Aires
2026 Sails: Nov 11, More...

Viking Ocean, Viking Vesta

7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Nov 11, More...

Viking Ocean, Viking Vesta

14 Night - Mediterranean & Italian Sojourn
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Nov 11, More...

MSC Cruises, MSC World Europa

6 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, La Spezia (Cinque Terre), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Nov 12, More...

Windstar, Star Legend

15 Night - Ocean Crossings
Starting in Malaga, Tangier, Casablanca, Morocco, Funchal, Bridgetown
2026 Sails: Nov 12, More...

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