Siem Reap Cruise Departures
Cruises that depart from Asia/Far East: Cambodia: Siem Reap
Cruises that visit Siem Reap
See all River Cruises that depart from Siem Reap
15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)
Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2026 Sails: Aug 24, Sep 21, Oct 5, Nov 30, More...
10 Night - Luxury Mekong and Temple Discovery Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Sep 19, Oct 3, Oct 31, Nov 28, 2027: Jan 2, Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, More...
12 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Sep 23, Oct 7, Nov 4, Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, Sep 22, Oct 6, Oct 20, Nov 17, More...
10 Night - Deeper and Further On the Mekong River
Starting in Siem Reap to the Tonle Sap, The Tonle Sap Lake and Kampong Chhnang, Tonle Sap River, Peam Chi Korng Pottery Village, Koh Trong Island, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Disembark Saigon, Siem Reap / Steung Trang, Kratie / Dolphin Ground, Koh Trong, Steung Trang / Peam Chi Korng, Peam Chi Korng / Pak Russei Crafts, Oudong / Kampong Tralach, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Oct 11, Dec 23, 2027: Oct 10, More...
7 Night - Classic Mekong
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Oct 24, 2027: Feb 13, Mar 13, Oct 9, Oct 23, Nov 20, 2028: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Apr 22, More...7 Night - Classic Mekong
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Oct 31, Nov 14, Dec 26, 2027: Mar 6, Mar 20, Oct 30, Nov 13, Dec 25, 2028: Jan 8, Jan 22, Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, More...
7 Night - Classic Mekong
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Nov 11, More...12 Night - Fascinating Vietnam, Cambodia & the Mekong River (Southbound)
Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 15, Nov 29, More...15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)
Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 15, Nov 29, More...
12 Night - Sailing Vietnam and Cambodia's Mekong River Aboard The
Starting in Siem Reap, Cambodia, Angkor, Steung Trang / Embark Ship, Angkor Ban / Prek Bang Kong, Kampong Tralach / Kampong Leaeng, Phnom Penh, Cruising the Mekong, Chau Doc, Vietnam, Binh Thanh Island / Cai Be, My Tho / Disembark Ship / Saigon (Ho Chi Minh City), Saigon
2027 Sails: Jan 13, Feb 24, More...
Cruises that depart from Asia/Far East: Cambodia: Siem Reap
Cruises that visit Siem Reap
See all River Cruises that depart from Siem Reap
Click on a cruise ship itinerary sailing from Siem Reap (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Siem Reap), please visit: Cruise Search or try our Virtual Cruise Advisor™.
15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2026 Sails: Aug 24, Sep 21, Oct 5, Nov 30, More...
10 Night - Luxury Mekong and Temple Discovery CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Sep 19, Oct 3, Oct 31, Nov 28, 2027: Jan 2, Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, More...
12 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Sep 23, Oct 7, Nov 4, Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, Sep 22, Oct 6, Oct 20, Nov 17, More...
10 Night - Deeper and Further On the Mekong RiverStarting in Siem Reap to the Tonle Sap, The Tonle Sap Lake and Kampong Chhnang, Tonle Sap River, Peam Chi Korng Pottery Village, Koh Trong Island, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Disembark Saigon, Siem Reap / Steung Trang, Kratie / Dolphin Ground, Koh Trong, Steung Trang / Peam Chi Korng, Peam Chi Korng / Pak Russei Crafts, Oudong / Kampong Tralach, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Oct 11, Dec 23, 2027: Oct 10, More...
7 Night - Classic MekongStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Oct 24, 2027: Feb 13, Mar 13, Oct 9, Oct 23, Nov 20, 2028: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Apr 22, More...
7 Night - Classic MekongStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Oct 31, Nov 14, Dec 26, 2027: Mar 6, Mar 20, Oct 30, Nov 13, Dec 25, 2028: Jan 8, Jan 22, Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, More...
7 Night - Classic MekongStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Nov 11, More...
12 Night - Fascinating Vietnam, Cambodia & the Mekong River (Southbound)Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 15, Nov 29, More...
15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 15, Nov 29, More...
12 Night - Sailing Vietnam and Cambodia's Mekong River Aboard TheStarting in Siem Reap, Cambodia, Angkor, Steung Trang / Embark Ship, Angkor Ban / Prek Bang Kong, Kampong Tralach / Kampong Leaeng, Phnom Penh, Cruising the Mekong, Chau Doc, Vietnam, Binh Thanh Island / Cai Be, My Tho / Disembark Ship / Saigon (Ho Chi Minh City), Saigon
2027 Sails: Jan 13, Feb 24, More...
